ID A0A2H5Q9F0_CITUN Unreviewed; 1591 AA.
AC A0A2H5Q9F0;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=Mandelate racemase/muconate lactonizing enzyme C-terminal domain-containing protein {ECO:0000259|SMART:SM00922};
GN ORFNames=CUMW_208610 {ECO:0000313|EMBL:GAY61269.1};
OS Citrus unshiu (Satsuma mandarin) (Citrus nobilis var. unshiu).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Sapindales; Rutaceae; Aurantioideae; Citrus.
OX NCBI_TaxID=55188 {ECO:0000313|EMBL:GAY61269.1, ECO:0000313|Proteomes:UP000236630};
RN [1] {ECO:0000313|EMBL:GAY61269.1, ECO:0000313|Proteomes:UP000236630}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Miyagawa wase {ECO:0000313|Proteomes:UP000236630};
RX PubMed=29259619; DOI=10.3389/fgene.2017.00180;
RA Shimizu T., Tanizawa Y., Mochizuki T., Nagasaki H., Yoshioka T., Toyoda A.,
RA Fujiyama A., Kaminuma E., Nakamura Y.;
RT "Draft sequencing of the heterozygous diploid genome of Satsuma (Citrus
RT unshiu Marc.) using a hybrid assembly approach.";
RL Front. Genet. 8:180-180(2017).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GAY61269.1}.
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DR EMBL; BDQV01000264; GAY61269.1; -; Genomic_DNA.
DR STRING; 55188.A0A2H5Q9F0; -.
DR Proteomes; UP000236630; Unassembled WGS sequence.
DR GO; GO:0070204; F:2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase activity; IEA:InterPro.
DR GO; GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
DR GO; GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
DR GO; GO:0009063; P:amino acid catabolic process; IEA:InterPro.
DR GO; GO:0009234; P:menaquinone biosynthetic process; IEA:InterPro.
DR CDD; cd07037; TPP_PYR_MenD; 1.
DR Gene3D; 3.40.50.970; -; 2.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR Gene3D; 3.20.20.120; Enolase-like C-terminal domain; 1.
DR Gene3D; 3.30.390.10; Enolase-like, N-terminal domain; 1.
DR Gene3D; 3.40.50.1220; TPP-binding domain; 1.
DR HAMAP; MF_01659; MenD; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR000073; AB_hydrolase_1.
DR InterPro; IPR029035; DHS-like_NAD/FAD-binding_dom.
DR InterPro; IPR036849; Enolase-like_C_sf.
DR InterPro; IPR029017; Enolase-like_N.
DR InterPro; IPR029065; Enolase_C-like.
DR InterPro; IPR018110; Mandel_Rmase/mucon_lact_enz_CS.
DR InterPro; IPR013342; Mandelate_racemase_C.
DR InterPro; IPR004433; MenaQ_synth_MenD.
DR InterPro; IPR032264; MenD_middle.
DR InterPro; IPR029061; THDP-binding.
DR InterPro; IPR012001; Thiamin_PyroP_enz_TPP-bd_dom.
DR NCBIfam; TIGR01927; menC_gam_Gplu; 1.
DR NCBIfam; TIGR00173; menD; 1.
DR PANTHER; PTHR42916; 2-SUCCINYL-5-ENOLPYRUVYL-6-HYDROXY-3-CYCLOHEXENE-1-CARBOXYLATE SYNTHASE; 1.
DR PANTHER; PTHR42916:SF1; PROTEIN PHYLLO, CHLOROPLASTIC; 1.
DR Pfam; PF00561; Abhydrolase_1; 1.
DR Pfam; PF13378; MR_MLE_C; 1.
DR Pfam; PF16582; TPP_enzyme_M_2; 1.
DR Pfam; PF02776; TPP_enzyme_N; 1.
DR SFLD; SFLDS00001; Enolase; 1.
DR SFLD; SFLDF00009; o-succinylbenzoate_synthase; 1.
DR SMART; SM00922; MR_MLE; 1.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR SUPFAM; SSF52467; DHS-like NAD/FAD-binding domain; 1.
DR SUPFAM; SSF51604; Enolase C-terminal domain-like; 1.
DR SUPFAM; SSF54826; Enolase N-terminal domain-like; 1.
DR SUPFAM; SSF52518; Thiamin diphosphate-binding fold (THDP-binding); 2.
DR PROSITE; PS00909; MR_MLE_2; 1.
PE 3: Inferred from homology;
KW Lyase {ECO:0000256|ARBA:ARBA00023239};
KW Manganese {ECO:0000256|ARBA:ARBA00023211};
KW Reference proteome {ECO:0000313|Proteomes:UP000236630}.
FT DOMAIN 1035..1131
FT /note="Mandelate racemase/muconate lactonizing enzyme C-
FT terminal"
FT /evidence="ECO:0000259|SMART:SM00922"
FT REGION 1..21
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1591 AA; 177175 MW; 7CCCFB4991285A07 CRC64;
MAQPKTSTVN NGKDKQTAAK PANGNSARFL SIIHSPYGFR HFNSIDLLRN SGSKVVEGLR
FDGPVMDVDE IMDCEEGDLV VETSITRTLP PALTLEHGLE SISEAVNKLK TDPPSSSSGV
LRFQVAVPPS AKALDWFCRQ PESSEVFPVF FLSRDMENPT SKSLYLNQNR GVFGIGAAVY
FTHPAWCDSE ERTKPKRYLS TNPIPITTYG FMDINFNTEP SCIKHEAGSF YFFVPQIELR
ELDDISILAA TLAWSNGMVC TFEQAIQSFE SSFCQLDNAI GMNYSLGDHV NINAVWASLL
IEECSRLGLT YFCIAPGSRS SPLAVAASTH PLITCIACYD ERSLAFHALG YARGSHRPAV
IITSSGTAVS NLLPAVVEAS QDFVPVLLLT ADRPPELQDA GANQAINQVN HFGSFVRFFF
SLPAPTDQIP ARMILTTLDA AVHWATSSPY GPVHINCPFR EPLDNSPKHW MSSCLKGLDI
WTSSIEPFTK YIQVQHSHAC KSYTYGQMAE VLELVQGVNK GLLLVGAVHN EDEIWAVLHL
ARHIRWPVVA DILSGLRLRK LLASFLETEQ NILFLDHLDH ALLSESVKDW IQFDVIIQIG
SRITSKRISQ MIEECFPCTY ILVDNHPCRH DPSHSVTHRI QSTIVQFVDF LLKVQVPHRS
SKWCSFLRAL DMMVASEISF QICTDYSLTE PHVAHELSRA LTSNSALFVG NSMAIRDVDM
YGRNWTTCTR TVADIMLNSE FPQQWIRVAG NRGASGIDGL LSTAIGFAVG CNKHVLCVVG
DISFLHDTNG LAILKQSLNH VQVKTKVELE EALSMSQHLG TDRVIEVESC IDANATFHSM
LRKFARQSAD HTLNVLSQFS VPDTISCSLS ICKICRMEYS LYRIQLCALP TSSYIDHNRS
RFCREGFILS LYLEDGSVGY GEVAPLEIHK ENLLDAEEQL RFLLHFMTGA KISYFLPLLK
GSFSSWIWST LGIPACEIFP SVRCGLEMAI LNAIAVKHGS SFLNILYPLT EIDEEISKRS
TSIKICALID SNKSPVEVAS IATTLVEEGF TAIKLKVARR ADPIKDAEVI QEVRKKVGHR
IELRVDANRN WTYQEALEFG FLVKDCDLQY IEEPVQNEED IIKYCEESGL PVALDETIDK
FQKDPLNMLE KYAHPGIVAI VIKPSVIGGF ENAGLIARWA QRHGKMAVVS AAFESGLGLS
AYIIFSSYLE LQNAYLCKVM NRELCPPVAQ GLGTYQWLKE DITTDPISIC HNSCSGFVEA
SVAKATHILQ NLQINNDVIC KTSMEEQVLR YQLNVNSKDF CSFIKVQEIG QRIDIQDNIL
LFLHGFLGTG EEWIPIMKAV SGSARCISID LPGHGGSKMQ NHEITLSIDV IADVLYKLIE
QITPGKVTLV GYSMGARIAL YMALRFSDKI KGTVIISGSP GLRDNIARKI RRAEDDSRAC
ALVTHGLQVF LDTWYTGELW ESLRSHPHFN RIVASRLLHE DVQSLSKALS DLSVGRQPPL
WEDLKLCSTP LLIVVGEKDK KFKSIAEKMC YELSHDEKGS DDLRNQIYEM VEIPNCGHAV
HLENPLPVIR AVRQFLTRVN QNSTSNPESN G
//
