ID A0A2H5Q9G3_CITUN Unreviewed; 1662 AA.
AC A0A2H5Q9G3;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=Mandelate racemase/muconate lactonizing enzyme C-terminal domain-containing protein {ECO:0000259|SMART:SM00922};
DE Flags: Fragment;
GN ORFNames=CUMW_208620 {ECO:0000313|EMBL:GAY61268.1};
OS Citrus unshiu (Satsuma mandarin) (Citrus nobilis var. unshiu).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Sapindales; Rutaceae; Aurantioideae; Citrus.
OX NCBI_TaxID=55188 {ECO:0000313|EMBL:GAY61268.1, ECO:0000313|Proteomes:UP000236630};
RN [1] {ECO:0000313|EMBL:GAY61268.1, ECO:0000313|Proteomes:UP000236630}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Miyagawa wase {ECO:0000313|Proteomes:UP000236630};
RX PubMed=29259619; DOI=10.3389/fgene.2017.00180;
RA Shimizu T., Tanizawa Y., Mochizuki T., Nagasaki H., Yoshioka T., Toyoda A.,
RA Fujiyama A., Kaminuma E., Nakamura Y.;
RT "Draft sequencing of the heterozygous diploid genome of Satsuma (Citrus
RT unshiu Marc.) using a hybrid assembly approach.";
RL Front. Genet. 8:180-180(2017).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GAY61268.1}.
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DR EMBL; BDQV01000264; GAY61268.1; -; Genomic_DNA.
DR STRING; 55188.A0A2H5Q9G3; -.
DR Proteomes; UP000236630; Unassembled WGS sequence.
DR GO; GO:0070204; F:2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase activity; IEA:InterPro.
DR GO; GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
DR GO; GO:0009063; P:amino acid catabolic process; IEA:InterPro.
DR GO; GO:0009234; P:menaquinone biosynthetic process; IEA:InterPro.
DR CDD; cd07037; TPP_PYR_MenD; 1.
DR CDD; cd02009; TPP_SHCHC_synthase; 1.
DR Gene3D; 3.40.50.970; -; 2.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR Gene3D; 3.20.20.120; Enolase-like C-terminal domain; 1.
DR Gene3D; 3.30.390.10; Enolase-like, N-terminal domain; 1.
DR Gene3D; 3.40.50.1220; TPP-binding domain; 1.
DR HAMAP; MF_01659; MenD; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR000073; AB_hydrolase_1.
DR InterPro; IPR029035; DHS-like_NAD/FAD-binding_dom.
DR InterPro; IPR036849; Enolase-like_C_sf.
DR InterPro; IPR029017; Enolase-like_N.
DR InterPro; IPR029065; Enolase_C-like.
DR InterPro; IPR018110; Mandel_Rmase/mucon_lact_enz_CS.
DR InterPro; IPR013342; Mandelate_racemase_C.
DR InterPro; IPR004433; MenaQ_synth_MenD.
DR InterPro; IPR032264; MenD_middle.
DR InterPro; IPR029061; THDP-binding.
DR InterPro; IPR012001; Thiamin_PyroP_enz_TPP-bd_dom.
DR InterPro; IPR011766; TPP_enzyme_TPP-bd.
DR NCBIfam; TIGR01927; menC_gam_Gplu; 1.
DR NCBIfam; TIGR00173; menD; 1.
DR PANTHER; PTHR42916; 2-SUCCINYL-5-ENOLPYRUVYL-6-HYDROXY-3-CYCLOHEXENE-1-CARBOXYLATE SYNTHASE; 1.
DR PANTHER; PTHR42916:SF1; PROTEIN PHYLLO, CHLOROPLASTIC; 1.
DR Pfam; PF00561; Abhydrolase_1; 1.
DR Pfam; PF13378; MR_MLE_C; 1.
DR Pfam; PF02775; TPP_enzyme_C; 1.
DR Pfam; PF16582; TPP_enzyme_M_2; 1.
DR Pfam; PF02776; TPP_enzyme_N; 1.
DR SFLD; SFLDG00180; muconate_cycloisomerase; 1.
DR SFLD; SFLDF00009; o-succinylbenzoate_synthase; 1.
DR SMART; SM00922; MR_MLE; 1.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR SUPFAM; SSF52467; DHS-like NAD/FAD-binding domain; 1.
DR SUPFAM; SSF51604; Enolase C-terminal domain-like; 1.
DR SUPFAM; SSF54826; Enolase N-terminal domain-like; 1.
DR SUPFAM; SSF52518; Thiamin diphosphate-binding fold (THDP-binding); 2.
DR PROSITE; PS00909; MR_MLE_2; 1.
PE 3: Inferred from homology;
KW Lyase {ECO:0000256|ARBA:ARBA00023239};
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Manganese {ECO:0000256|ARBA:ARBA00023211};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000236630};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 1120..1216
FT /note="Mandelate racemase/muconate lactonizing enzyme C-
FT terminal"
FT /evidence="ECO:0000259|SMART:SM00922"
FT REGION 1..32
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 12..32
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:GAY61268.1"
SQ SEQUENCE 1662 AA; 185218 MW; F4AF76FF2A2D05CD CRC64;
GPRKWPSPKL QPSITGKINR QQQSQQTATA PASSALSIRL KSSISKHRLT KSLGIPKPSP
PLTFLTRISG FRHFNSIDLL RNSGSKVVEG LRFDGPVMDV DEIMDCEEGD LVVETSITRT
LPPALTLEHG LESISEAVNK LKTDPPSSSS GVLRFQVAVP PSAKALDWFC RQPESSEVFP
VFFLSRDMEN PTSKSLYLNQ NRGVFGIGAA VYFTHPAWCD SEERTKPKRY LSTNPIPITT
YGFMDINFNT EPSCIKHEAG SFYFFVPQIE LRELDDISIL AATLAWSNGM VCTFEQAIQS
FESSFCQLDN AIGMNYSLGD HVNINAVWAS LLIEECSRLG LTYFCIAPGS RSSPLAVAAS
THPLITCIAC YDERSLAFHA LGYARGSHRP AVIITSSGTA VSNLLPAVVE ASQDFVPVLL
LTADRPPELQ DAGANQAINQ VNHFGSFVRF FFSLPAPTDQ IPARMILTTL DAAVHWATSS
PYGPVHINCP FREPLDNSPK HWMSSCLKGL DIWTSSIEPF TKYIQVQHSH ACKSYTYGQM
AEVLELVQGV NKGLLLVGAV HNEDEIWAVL HLARHIRWPV VADILSGLRL RKLLASFLET
EQNILFLDHL DHALLSESVK DWIQFDVIIQ IGSRITSKRI SQMIEECFPC TYILVDNHPC
RHDPSHSVTH RIQSTIVQFV DFLLKVQVPH RSSKWCSFLR ALDMMVASEI SFQICTDYSL
TEPHVAHELS RALTSNSALF VGNSMAIRDV DMYGRNWTTC TRTVADIMLN SEFPQQWIRV
AGNRGASGID GLLSTAIGFA VGCNKHVLCV VGDISFLHDT NGLAILKQRM KRKPILMLVM
NNHGGAIFSL LPIADRTEPR ILDQYFYTTH NISIQNLCLA HGLNHVQVKT KVELEEALSM
SQHLGTDRVI EVESCIDANA TFHSMLRKFA RQSADHTLNV LSQFSVPDTI SCSLSICKIC
RMEYSLYRIQ LCALPTSSYI DHNRSRFCRE GFILSLYLED GSVGYGEVAP LEIHKENLLD
AEEQLRFLLH FMTGAKISYF LPLLKGSFSS WIWSTLGIPA CEIFPSVRCG LEMAILNAIA
VKHGSSFLNI LYPLTEIDEE ISKRSTSIKI CALIDSNKSP VEVASIATTL VEEGFTAIKL
KVARRADPIK DAEVIQEVRK KVGHRIELRV DANRNWTYQE ALEFGFLVKD CDLQYIEEPV
QNEEDIIKYC EESGLPVALD ETIDKFQKDP LNMLEKYAHP GIVAIVIKPS VIGGFENAGL
IARWAQRHGK MAVVSAAFES GLGLSAYIIF SSYLELQNAY LCKVMNRELC PPVAQGLGTY
QWLKEDITTD PISICHNSCS GFVEASVAKA THILQNLQIN NDVICKTSME EQVLRYQLNV
NSKDFCSFIK VQEIGQRIDI QDNILLFLHG FLGTGEEWIP IMKAVSGSAR CISIDLPGHG
GSKMQNHVAK ATQEITTKAT QEITTKATQE ITLSIDVIAD VLYKLIEQIT PGKVTLVGYS
MGARIALYMA LRFSDKIKGT VIISGSPGLR DNIARKIRRA EDDSRACALV THGLQVFLDT
WYTGELWERP LWEDLKLCST PLLIVVGEKD KKFKSIAEKM CYELSHDEKG SDDLRNQIYE
MVEIPNCGHA VHLENPLPVI RAVRQFLTRV NQNSTSNPES NG
//
