ID A0A2H5QF45_CITUN Unreviewed; 710 AA.
AC A0A2H5QF45;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE RecName: Full=Cyclic nucleotide-binding domain-containing protein {ECO:0000259|PROSITE:PS50042};
GN ORFNames=CUMW_224150 {ECO:0000313|EMBL:GAY63258.1};
OS Citrus unshiu (Satsuma mandarin) (Citrus nobilis var. unshiu).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Sapindales; Rutaceae; Aurantioideae; Citrus.
OX NCBI_TaxID=55188 {ECO:0000313|EMBL:GAY63258.1};
RN [1] {ECO:0000313|EMBL:GAY63258.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=29259619; DOI=10.3389/fgene.2017.00180;
RA Shimizu T., Tanizawa Y., Mochizuki T., Nagasaki H., Yoshioka T., Toyoda A.,
RA Fujiyama A., Kaminuma E., Nakamura Y.;
RT "Draft sequencing of the heterozygous diploid genome of Satsuma (Citrus
RT unshiu Marc.) using a hybrid assembly approach.";
RL Front. Genet. 8:180-180(2017).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the cyclic nucleotide-gated cation channel (TC
CC 1.A.1.5) family. {ECO:0000256|ARBA:ARBA00010486}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GAY63258.1}.
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DR EMBL; BDQV01000342; GAY63258.1; -; Genomic_DNA.
DR EMBL; BDQV01000342; GAY63259.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2H5QF45; -.
DR STRING; 55188.A0A2H5QF45; -.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.
DR GO; GO:0030553; F:cGMP binding; IEA:UniProtKB-KW.
DR GO; GO:0005249; F:voltage-gated potassium channel activity; IEA:InterPro.
DR CDD; cd00038; CAP_ED; 1.
DR Gene3D; 1.10.287.70; -; 1.
DR Gene3D; 1.10.287.630; Helix hairpin bin; 1.
DR Gene3D; 2.60.120.10; Jelly Rolls; 1.
DR InterPro; IPR000595; cNMP-bd_dom.
DR InterPro; IPR018490; cNMP-bd_dom_sf.
DR InterPro; IPR005821; Ion_trans_dom.
DR InterPro; IPR003938; K_chnl_volt-dep_EAG/ELK/ERG.
DR InterPro; IPR014710; RmlC-like_jellyroll.
DR PANTHER; PTHR45651; CYCLIC NUCLEOTIDE-GATED ION CHANNEL 15-RELATED-RELATED; 1.
DR PANTHER; PTHR45651:SF16; PROTEIN CNGC15A; 1.
DR Pfam; PF00520; Ion_trans; 1.
DR PRINTS; PR01463; EAGCHANLFMLY.
DR SMART; SM00100; cNMP; 1.
DR SUPFAM; SSF51206; cAMP-binding domain-like; 1.
DR SUPFAM; SSF81324; Voltage-gated potassium channels; 1.
DR PROSITE; PS50042; CNMP_BINDING_3; 1.
PE 3: Inferred from homology;
KW Calmodulin-binding {ECO:0000256|ARBA:ARBA00022860};
KW cGMP {ECO:0000256|ARBA:ARBA00022535};
KW cGMP-binding {ECO:0000256|ARBA:ARBA00022992};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022992};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 91..109
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 180..201
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 213..230
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 251..272
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 326..346
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 367..394
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 480..565
FT /note="Cyclic nucleotide-binding"
FT /evidence="ECO:0000259|PROSITE:PS50042"
FT REGION 647..667
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 651..667
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 710 AA; 81770 MW; 6F11C3A772D85208 CRC64;
MADARHKFIR FQEDPEMTKY TSPKRGYISK FTNKFVAVSE RELCSNKFGN DAKGKTFHKR
GLSRVFSEDY ELVEKVILDP RGPIINRWNK IFLVACLVSL FVDPLFFYLP EAKKNACINV
SVPLEIILTV IRSLADAFYF VRIFIRFRTA FVAPSSRVLG RGDLVIDPSK ISSRYLRKDF
WLDIMAAQPI PQLLLWAVIP YLKGSSMVST KNVIRLIIIF QYLLRLYLTF PLSYQIIKAS
GVLLETSWAG AAYNLMLYML ASHVLGACWY LLSVERQEEC WRKVCRSHHL ECNIGFFDCH
LVKDSSRVNL FQMSNISSLC DPKSNYYQFG IFADAVILGV TASRFLDKYF YCLWWGLRNL
SSLGQNLFTS TFVWEINFAI AIAILGLTLF GLLIGNMQTY LQSTTVRLEE WRIRRTDTEK
WMHHRQLPHG LKQSVRKYDQ YRWVATRGVD EESILDGLPT DLRRDIKRHL CLDLVRQVPL
FDLMDDRMLV AVCERLKPRL CTPGTCPVRE EDPVNEMLFI VRGHLDSYTT GGGRTGFFNS
CRIGPGDFCG EELLTWALDP RPSVILPSST RTVKAITEVE AFAFVDEDLK FVASQYRKLH
CKQLRHVFRC HSPQWRTWAA CFIQAAWFRY KRRKEAAELK KREGMISMSD KATDQKESSS
PSMGSGQFTS YAAKLAASTR RGGSKRCGTE FDILSSLQKP NEPDFTVVDR
//
