ID A0A2H5QN49_CITUN Unreviewed; 765 AA.
AC A0A2H5QN49;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE RecName: Full=non-specific serine/threonine protein kinase {ECO:0000256|ARBA:ARBA00012513};
DE EC=2.7.11.1 {ECO:0000256|ARBA:ARBA00012513};
GN ORFNames=CUMW_245710 {ECO:0000313|EMBL:GAY66058.1};
OS Citrus unshiu (Satsuma mandarin) (Citrus nobilis var. unshiu).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Sapindales; Rutaceae; Aurantioideae; Citrus.
OX NCBI_TaxID=55188 {ECO:0000313|EMBL:GAY66058.1, ECO:0000313|Proteomes:UP000236630};
RN [1] {ECO:0000313|EMBL:GAY66058.1, ECO:0000313|Proteomes:UP000236630}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Miyagawa wase {ECO:0000313|Proteomes:UP000236630};
RX PubMed=29259619; DOI=10.3389/fgene.2017.00180;
RA Shimizu T., Tanizawa Y., Mochizuki T., Nagasaki H., Yoshioka T., Toyoda A.,
RA Fujiyama A., Kaminuma E., Nakamura Y.;
RT "Draft sequencing of the heterozygous diploid genome of Satsuma (Citrus
RT unshiu Marc.) using a hybrid assembly approach.";
RL Front. Genet. 8:180-180(2017).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GAY66058.1}.
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DR EMBL; BDQV01000536; GAY66058.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2H5QN49; -.
DR STRING; 55188.A0A2H5QN49; -.
DR Proteomes; UP000236630; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0042803; F:protein homodimerization activity; IEA:UniProt.
DR GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd14066; STKc_IRAK; 1.
DR Gene3D; 2.130.10.30; Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II; 1.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR044815; CCR1-4.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR017441; Protein_kinase_ATP_BS.
DR InterPro; IPR009091; RCC1/BLIP-II.
DR InterPro; IPR001245; Ser-Thr/Tyr_kinase_cat_dom.
DR InterPro; IPR008271; Ser/Thr_kinase_AS.
DR PANTHER; PTHR46146; SERINE/THREONINE-PROTEIN KINASE-LIKE PROTEIN CCR4; 1.
DR PANTHER; PTHR46146:SF4; SERINE_THREONINE-PROTEIN KINASE-LIKE PROTEIN CCR4; 1.
DR Pfam; PF07714; PK_Tyr_Ser-Thr; 1.
DR Pfam; PF13540; RCC1_2; 2.
DR SMART; SM00220; S_TKc; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR SUPFAM; SSF50985; RCC1/BLIP-II; 1.
DR PROSITE; PS00107; PROTEIN_KINASE_ATP; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU10141}; Kinase {ECO:0000256|ARBA:ARBA00022777};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU10141}; Reference proteome {ECO:0000313|Proteomes:UP000236630};
KW Serine/threonine-protein kinase {ECO:0000256|ARBA:ARBA00022527};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..28
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 29..765
FT /note="non-specific serine/threonine protein kinase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5014174562"
FT TRANSMEM 364..387
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 458..747
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT REGION 407..427
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 413..427
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 486
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10141"
SQ SEQUENCE 765 AA; 83350 MW; BF3E548186791DAF CRC64;
MFNEPNNPFL LTTLLLLFFV SLVPFNSSLS TFSISETGNQ SLVCALIPSS RPGDFSLNCS
IPQLIPVNPN ASFASIVSGD GFLCTLITFS ASSSSVMHCW RFSADGIIND YKRIYRGPAL
KQLEAGNSHI CGLVNGTNDL HWWQWHDFNS TSTHNFSNIA VGEDFVCGLL ENGTITCFGS
RNSPTSVTQK VPSGIFRVVA AGFRHVCAID DDQELRCWGD SVGEVPQGKF TALALGENRS
CALRNNQKVV CWGQNGFTLP DSLQGIYFVS IEAKRSVFCG VLASNYSLYC WGNENFSSNH
MVFESVLPGP CTNTCPCLML PGSGNVCGEG QIICQPCFEK TSVTPSPTPQ PPESGSGGGW
SGRMVALLVV GCLGSLVVVL VSAFFGYKHC KCKGCRVHDS GPLDEAVAQA QSAQPPMPPP
PPSPPVLEKK LSQLASMGNA GRLEEFSLEI LLEATNNFSE DHKIGSGSFG AVYKATLDDG
RQVAVKRAEI SSTSSYAIGT KRQEDKDNAF INELESLSRL HHKNLVRLLG FCEDRNERVL
IYEYLENGTL HDHLHNPQSS SPLKSWPARI KVALDAARGI EYLHEYAVPS IIHRDIKSSN
VLLDATWTAK VSDFGLSLIG PEDDESHLSL RAAGTVGYMD PEYYRLQQLT EKSDVYSFGV
VLLEILSGYR AIHRTDNGTP RNVVDFVVPY IVRDEIHRVL DRNVPPPTPF EIEAVAYVGY
LAADCVTLEG RNRPSMTEIV NSLERALAAC LVSPSISRSA TSSST
//
