ID   A0A2H6KEA5_9APIC        Unreviewed;       487 AA.
AC   A0A2H6KEA5;
DT   28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT   28-FEB-2018, sequence version 1.
DT   22-FEB-2023, entry version 14.
DE   SubName: Full=Domain containing protein {ECO:0000313|EMBL:GBE61317.1};
GN   ORFNames=BOVATA_028100 {ECO:0000313|EMBL:GBE61317.1};
OS   Babesia ovata.
OC   Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Piroplasmida;
OC   Babesiidae; Babesia.
OX   NCBI_TaxID=189622 {ECO:0000313|EMBL:GBE61317.1, ECO:0000313|Proteomes:UP000236319};
RN   [1] {ECO:0000313|EMBL:GBE61317.1, ECO:0000313|Proteomes:UP000236319}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Miyake {ECO:0000313|EMBL:GBE61317.1,
RC   ECO:0000313|Proteomes:UP000236319};
RX   PubMed=29078748; DOI=10.1186/s12864-017-4230-4;
RA   Yamagishi J., Asada M., Hakimi H., Tanaka T.Q., Sugimoto C., Kawazu S.;
RT   "Whole-genome assembly of Babesia ovata and comparative genomics between
RT   closely related pathogens.";
RL   BMC Genomics 18:832-832(2017).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:GBE61317.1}.
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DR   EMBL; BDSA01000003; GBE61317.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2H6KEA5; -.
DR   VEuPathDB; PiroplasmaDB:BOVATA_028100; -.
DR   OrthoDB; 3030820at2759; -.
DR   Proteomes; UP000236319; Unassembled WGS sequence.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   Gene3D; 3.40.525.10; CRAL-TRIO lipid binding domain; 1.
DR   Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR   InterPro; IPR001251; CRAL-TRIO_dom.
DR   InterPro; IPR036865; CRAL-TRIO_dom_sf.
DR   InterPro; IPR008936; Rho_GTPase_activation_prot.
DR   InterPro; IPR000198; RhoGAP_dom.
DR   Pfam; PF13716; CRAL_TRIO_2; 1.
DR   Pfam; PF00620; RhoGAP; 1.
DR   SMART; SM00324; RhoGAP; 1.
DR   SUPFAM; SSF52087; CRAL/TRIO domain; 1.
DR   SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000236319}.
FT   DOMAIN          221..394
FT                   /note="Rho-GAP"
FT                   /evidence="ECO:0000259|SMART:SM00324"
FT   REGION          397..487
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        397..415
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        418..433
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        437..451
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   487 AA;  54244 MW;  CA12BB8D3B592407 CRC64;
     MASVIALYSV PYDSDAESTE QYGKSYAQML SEDFNEDGFD DPNLLKCLGK GPSGEAVILV
     VPSVSARVRN NHEDALRLMV KKLNRFCSSK YSLLVCQTCT TWSDYNSYNF VNQWYDMLPK
     GSKKNLEKVY MVHSAYTTKT MLTCMTPFAK ARVWEKIEFV DKLGDLLKRL RLDTKNMLRN
     FPYAVQRAEE IALGIETPLS VFGTEMWILA LRVGCPFKGF PLIPPAVAHV LTKIESPEVI
     DTPNLLNLQC GPEVLYAAVG AYELLGEGCT VDSPETAVAL FKLLVDTHVG GLIGPKAYIT
     LKNALLQGSS NEELVQMMAK VTNEFQPVQK DCIFCIIKTL RAIARRASRN GMTVKAVSKI
     MAGSFFRPLS PDPYCFKAIQ SSEMVLGTMI EKPDMFFKRE KEPHEREEGR TKTVKHSSHT
     KSSSSSSAAG PRLSKSPSMR AREELQRIAQ RKEAARGSAS PHSVERTPTA APAMDEEESE
     QITEIEE
//