ID A0A2H9LBI0_9ARCH Unreviewed; 381 AA.
AC A0A2H9LBI0;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 24-JAN-2024, entry version 12.
DE RecName: Full=Protein-export membrane protein SecF {ECO:0000256|HAMAP-Rule:MF_01464};
GN Name=secF {ECO:0000256|HAMAP-Rule:MF_01464};
GN ORFNames=COT15_03535 {ECO:0000313|EMBL:PIU21202.1};
OS Candidatus Diapherotrites archaeon CG08_land_8_20_14_0_20_34_12.
OC Archaea; Candidatus Diapherotrites.
OX NCBI_TaxID=1974404 {ECO:0000313|EMBL:PIU21202.1, ECO:0000313|Proteomes:UP000229798};
RN [1] {ECO:0000313|EMBL:PIU21202.1, ECO:0000313|Proteomes:UP000229798}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CG08_land_8_20_14_0_20_34_12 {ECO:0000313|EMBL:PIU21202.1};
RA Probst A.J., Ladd B., Jarett J.K., Geller-Mcgrath D.E., Sieber C.M.,
RA Emerson J.B., Anantharaman K., Thomas B.C., Malmstrom R., Stieglmeier M.,
RA Klingl A., Woyke T., Ryan C.M., Banfield J.F.;
RT "Depth-based differentiation of microbial function through sediment-hosted
RT aquifers and enrichment of novel symbionts in the deep terrestrial
RT subsurface.";
RL Submitted (SEP-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Involved in protein export. {ECO:0000256|HAMAP-
CC Rule:MF_01464}.
CC -!- SUBUNIT: Part of the protein translocation apparatus. Forms a complex
CC with SecD. {ECO:0000256|HAMAP-Rule:MF_01464}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|HAMAP-Rule:MF_01464};
CC Multi-pass membrane protein {ECO:0000256|HAMAP-Rule:MF_01464}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the SecD/SecF family. SecF subfamily.
CC {ECO:0000256|HAMAP-Rule:MF_01464}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|HAMAP-Rule:MF_01464}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PIU21202.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; PEXL01000038; PIU21202.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2H9LBI0; -.
DR Proteomes; UP000229798; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0065002; P:intracellular protein transmembrane transport; IEA:UniProtKB-UniRule.
DR GO; GO:0006605; P:protein targeting; IEA:UniProtKB-UniRule.
DR Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 1.
DR HAMAP; MF_01464_A; SecF_A; 1.
DR InterPro; IPR022813; SecD/SecF_arch_bac.
DR InterPro; IPR048634; SecD_SecF_C.
DR InterPro; IPR024921; SecF_arc.
DR PANTHER; PTHR30081; PROTEIN-EXPORT MEMBRANE PROTEIN SEC; 1.
DR PANTHER; PTHR30081:SF11; PROTEIN-EXPORT MEMBRANE PROTEIN SECF; 1.
DR Pfam; PF02355; SecD_SecF; 1.
DR SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475, ECO:0000256|HAMAP-
KW Rule:MF_01464};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|HAMAP-Rule:MF_01464};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927, ECO:0000256|HAMAP-
KW Rule:MF_01464};
KW Translocation {ECO:0000256|ARBA:ARBA00023010, ECO:0000256|HAMAP-
KW Rule:MF_01464};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|HAMAP-
KW Rule:MF_01464};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989, ECO:0000256|HAMAP-
KW Rule:MF_01464};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|HAMAP-Rule:MF_01464}.
FT TRANSMEM 36..57
FT /note="Helical"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01464"
FT TRANSMEM 221..240
FT /note="Helical"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01464"
FT TRANSMEM 260..293
FT /note="Helical"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01464"
FT TRANSMEM 314..337
FT /note="Helical"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01464"
FT TRANSMEM 343..371
FT /note="Helical"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01464"
FT DOMAIN 200..373
FT /note="Protein export membrane protein SecD/SecF C-
FT terminal"
FT /evidence="ECO:0000259|Pfam:PF02355"
SQ SEQUENCE 381 AA; 42338 MW; 90DE6F36FE11A871 CRC64;
MLIKKPKISG FLGSFLLVDS MSEKKSILPN IYKGNYWKYS IIPTILFFVF LFMALVYPGI
PQGIDLKGGN MLLIKTAKAH DAKTIEAALT SKFELEDISV TTITSPTSPG VMIQFSKNKF
FFDNDLIYKE GAVLLKAGDE AGAISKFETV LTALSSKISI DNKPKTAQDL QEFTALKIDE
AKQVFYNDVQ EFMRAQLNEA NLAFQIKEVA PTIGAIFWDN ALFVAFIALI CIFIVIFLFF
RELIPTLAIV QAATFDVATA LGGMALFGIP LGIATIPALL MIVGYSIDTD ILLTTRILKH
RELNARDQAY KSMATGLTMT GTAIAAAFIM CILSYFFQMF AIFDIAFVLF FGLIGDLIST
WLMNAQILIW YAERTINKVR K
//
