ID A0A2H9LGD6_9ARCH Unreviewed; 440 AA.
AC A0A2H9LGD6;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 24-JAN-2024, entry version 20.
DE RecName: Full=serine--tRNA ligase {ECO:0000256|ARBA:ARBA00012840};
DE EC=6.1.1.11 {ECO:0000256|ARBA:ARBA00012840};
DE AltName: Full=Seryl-tRNA synthetase {ECO:0000256|ARBA:ARBA00031113};
GN ORFNames=COT14_01835 {ECO:0000313|EMBL:PIU22310.1};
OS Candidatus Diapherotrites archaeon CG08_land_8_20_14_0_20_30_16.
OC Archaea; Candidatus Diapherotrites.
OX NCBI_TaxID=1974403 {ECO:0000313|EMBL:PIU22310.1, ECO:0000313|Proteomes:UP000230520};
RN [1] {ECO:0000313|EMBL:PIU22310.1, ECO:0000313|Proteomes:UP000230520}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CG08_land_8_20_14_0_20_30_16 {ECO:0000313|EMBL:PIU22310.1};
RA Probst A.J., Ladd B., Jarett J.K., Geller-Mcgrath D.E., Sieber C.M.,
RA Emerson J.B., Anantharaman K., Thomas B.C., Malmstrom R., Stieglmeier M.,
RA Klingl A., Woyke T., Ryan C.M., Banfield J.F.;
RT "Depth-based differentiation of microbial function through sediment-hosted
RT aquifers and enrichment of novel symbionts in the deep terrestrial
RT subsurface.";
RL Submitted (SEP-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PIU22310.1}.
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DR EMBL; PEXK01000030; PIU22310.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2H9LGD6; -.
DR Proteomes; UP000230520; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004828; F:serine-tRNA ligase activity; IEA:UniProtKB-EC.
DR GO; GO:0006434; P:seryl-tRNA aminoacylation; IEA:InterPro.
DR CDD; cd00770; SerRS_core; 1.
DR Gene3D; 1.10.287.40; Serine-tRNA synthetase, tRNA binding domain; 1.
DR InterPro; IPR002314; aa-tRNA-synt_IIb.
DR InterPro; IPR006195; aa-tRNA-synth_II.
DR InterPro; IPR045864; aa-tRNA-synth_II/BPL/LPL.
DR InterPro; IPR002317; Ser-tRNA-ligase_type_1.
DR InterPro; IPR015866; Ser-tRNA-synth_1_N.
DR InterPro; IPR042103; SerRS_1_N_sf.
DR InterPro; IPR033729; SerRS_core.
DR InterPro; IPR010978; tRNA-bd_arm.
DR NCBIfam; TIGR00414; serS; 1.
DR PANTHER; PTHR11778:SF7; SERINE--TRNA LIGASE, CYTOPLASMIC-RELATED; 1.
DR PANTHER; PTHR11778; SERYL-TRNA SYNTHETASE; 1.
DR Pfam; PF02403; Seryl_tRNA_N; 1.
DR Pfam; PF00587; tRNA-synt_2b; 1.
DR PIRSF; PIRSF001529; Ser-tRNA-synth_IIa; 1.
DR PRINTS; PR00981; TRNASYNTHSER.
DR SUPFAM; SSF55681; Class II aaRS and biotin synthetases; 1.
DR SUPFAM; SSF46589; tRNA-binding arm; 1.
DR PROSITE; PS50862; AA_TRNA_LIGASE_II; 1.
PE 4: Predicted;
KW Aminoacyl-tRNA synthetase {ECO:0000256|ARBA:ARBA00023146};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Ligase {ECO:0000256|ARBA:ARBA00022598, ECO:0000313|EMBL:PIU22310.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}.
FT DOMAIN 199..428
FT /note="Aminoacyl-transfer RNA synthetases class-II family
FT profile"
FT /evidence="ECO:0000259|PROSITE:PS50862"
FT COILED 14..105
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 440 AA; 51287 MW; E12E9D4F533C19F8 CRC64;
MLDIALFRND KDFKKLLESE KNRFRETKNA EETKKYDELW KKAKQTCEEK KAEKNKITKE
IAELAKNKKP IDQLKEKSKK IDTEIKDLEQ KQIEYLKSRD KYRSEVGNIL WHNTTIGQGE
ENNHLIKCCG KAKVQKSHIK QFKTLSGGKM QFEELKFNPK SHVDIGLEKD LFDLERAAKI
SGSRFYFLKN KLAILHLSIL RFAIDKLMKK GFNFMYTPFI VNKDTIEKTA ELSDFEEMLY
KVGNDQFLIA TAEQTLAGFH MDELIPKDSL PLKYVGLSSC FRREAGSHTK DTRGIFRVHQ
FDKVEQYIFC LPEDSEKIHN EMIKNEEEII QELELPYRLM DICSSDLNLT AAKKNDLEAW
MPVQGTFREL GSGSITTDYQ TRNLNIKYED KNEKFVVHSL NCTILASPRI LTAIIENHQT
KEGKINIPKA LWLYTGFKEI
//
