ID   A0A2H9N9N1_9ARCH        Unreviewed;       496 AA.
AC   A0A2H9N9N1;
DT   28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT   28-FEB-2018, sequence version 1.
DT   24-JAN-2024, entry version 14.
DE   SubName: Full=Radical SAM protein {ECO:0000313|EMBL:PIX31572.1};
GN   ORFNames=COZ60_03835 {ECO:0000313|EMBL:PIX31572.1};
OS   Candidatus Bathyarchaeota archaeon CG_4_8_14_3_um_filter_42_8.
OC   Archaea; Candidatus Bathyarchaeota.
OX   NCBI_TaxID=1974384 {ECO:0000313|EMBL:PIX31572.1, ECO:0000313|Proteomes:UP000230737};
RN   [1] {ECO:0000313|EMBL:PIX31572.1, ECO:0000313|Proteomes:UP000230737}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CG_4_8_14_3_um_filter_42_8 {ECO:0000313|EMBL:PIX31572.1};
RA   Probst A.J., Ladd B., Jarett J.K., Geller-Mcgrath D.E., Sieber C.M.,
RA   Emerson J.B., Anantharaman K., Thomas B.C., Malmstrom R., Stieglmeier M.,
RA   Klingl A., Woyke T., Ryan C.M., Banfield J.F.;
RT   "Depth-based differentiation of microbial function through sediment-hosted
RT   aquifers and enrichment of novel symbionts in the deep terrestrial
RT   subsurface.";
RL   Submitted (SEP-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PIX31572.1}.
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DR   EMBL; PFIN01000205; PIX31572.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2H9N9N1; -.
DR   Proteomes; UP000230737; Unassembled WGS sequence.
DR   GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0008168; F:methyltransferase activity; IEA:InterPro.
DR   CDD; cd01335; Radical_SAM; 1.
DR   Gene3D; 3.20.20.70; Aldolase class I; 1.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR034471; GDGT/MA_synthase.
DR   InterPro; IPR034474; Methyltransferase_Class_D.
DR   InterPro; IPR007197; rSAM.
DR   PANTHER; PTHR43306; 7,8-DIHYDRO-6-HYDROXYMETHYLPTERIN DIMETHYLTRANSFERASE; 1.
DR   PANTHER; PTHR43306:SF1; 7,8-DIHYDRO-6-HYDROXYMETHYLPTERIN DIMETHYLTRANSFERASE; 1.
DR   Pfam; PF13353; Fer4_12; 1.
DR   Pfam; PF04055; Radical_SAM; 1.
DR   SFLD; SFLDF00385; 7_8-dihydro-6-hydroxymethylpte; 1.
DR   SFLD; SFLDS00029; Radical_SAM; 1.
DR   SFLD; SFLDG01067; SPASM/twitch_domain_containing; 1.
DR   SUPFAM; SSF102114; Radical SAM enzymes; 1.
DR   PROSITE; PS51918; RADICAL_SAM; 1.
PE   4: Predicted;
KW   Iron {ECO:0000256|ARBA:ARBA00023004};
KW   Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691}.
FT   DOMAIN          85..309
FT                   /note="Radical SAM core"
FT                   /evidence="ECO:0000259|PROSITE:PS51918"
SQ   SEQUENCE   496 AA;  56753 MW;  96AFDCA29054F33F CRC64;
     MRFIKETKSI CPECLKVLDA TIFEEDGKVF IKKECPEHGF FQDVYWSDYE QYLRAERFRY
     DGDGLKNPRT KTVNGCPYDC GICPQHKSHT ALAIIDVTNR CNLKCPVCFA NAAAAGYVYE
     PTKEEIGSML ENLRKNEPVP ATALQFSGGE PTVRNDLFEL IRMAKELGFR HVEVNTNGLR
     LAQSVDYCKG LKEAGMSTIY LQFDGLTQEV YKFIRGIDLL DIKMKAIENC RKAGINSMVL
     VVTLIKGVND NQLGDIIRFA VQNFDVIRCI NVQPVSLCGR LPQRERDKMR ITIPDFMRLV
     EEQTNGKIKV SDFYPVPTVV PISKAVGALK DKRYVEFTAH PHCGMATYVF IENGEIIPIT
     RYGNVDKFVD VMKKVYDDAS KGNKNKAKLH LVGALRYIKF SFLRKHVWRV IREGSYEALG
     DLQRKAILLS AMHFMDPYNF DLERVQRCVI HYAVPDGRII PFCTMNSIHR PQIERKLGMS
     IKEWQGKHKV EITQYA
//