ID A0A2H9TPF5_9FUNG Unreviewed; 728 AA.
AC A0A2H9TPF5;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=Histone deacetylase domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=PSACC_00555 {ECO:0000313|EMBL:PJF19637.1};
OS Paramicrosporidium saccamoebae.
OC Eukaryota; Fungi; Fungi incertae sedis; Cryptomycota;
OC Cryptomycota incertae sedis; Paramicrosporidium.
OX NCBI_TaxID=1246581 {ECO:0000313|EMBL:PJF19637.1, ECO:0000313|Proteomes:UP000240830};
RN [1] {ECO:0000313|EMBL:PJF19637.1, ECO:0000313|Proteomes:UP000240830}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KSL3 {ECO:0000313|EMBL:PJF19637.1,
RC ECO:0000313|Proteomes:UP000240830};
RA Quandt C.A., Beaudet D., Corsaro D., Michel R., Corradi N., James T.;
RT "The genome of Paramicrosporidium saccamoebae is the missing link in
RT understanding Cryptomycota and Microsporidia evolution.";
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PJF19637.1}.
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DR EMBL; MTSL01000050; PJF19637.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2H9TPF5; -.
DR STRING; 1246581.A0A2H9TPF5; -.
DR Proteomes; UP000240830; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003899; F:DNA-directed 5'-3' RNA polymerase activity; IEA:InterPro.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0006351; P:DNA-templated transcription; IEA:InterPro.
DR GO; GO:0010468; P:regulation of gene expression; IEA:UniProt.
DR Gene3D; 3.40.800.20; Histone deacetylase domain; 1.
DR Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR InterPro; IPR019154; Arb2-like_domain.
DR InterPro; IPR000286; His_deacetylse.
DR InterPro; IPR023801; His_deacetylse_dom.
DR InterPro; IPR037138; His_deacetylse_dom_sf.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR InterPro; IPR005570; RPABC3.
DR InterPro; IPR023696; Ureohydrolase_dom_sf.
DR PANTHER; PTHR10625:SF4; HISTONE DEACETYLASE 6, ISOFORM G; 1.
DR PANTHER; PTHR10625; HISTONE DEACETYLASE HDAC1-RELATED; 1.
DR Pfam; PF09757; Arb2; 1.
DR Pfam; PF00850; Hist_deacetyl; 1.
DR Pfam; PF03870; RNA_pol_Rpb8; 1.
DR PRINTS; PR01270; HDASUPER.
DR SMART; SM00658; RPOL8c; 1.
DR SUPFAM; SSF52768; Arginase/deacetylase; 1.
DR SUPFAM; SSF50249; Nucleic acid-binding proteins; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 4: Predicted;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000240830}.
FT DOMAIN 190..467
FT /note="Histone deacetylase"
FT /evidence="ECO:0000259|Pfam:PF00850"
FT DOMAIN 543..724
FT /note="Arb2-like"
FT /evidence="ECO:0000259|Pfam:PF09757"
SQ SEQUENCE 728 AA; 79708 MW; CBE82514B3CE4FE8 CRC64;
MPFPRGDDLV WDFKPGPARS AVSSSSTSAC AMTDFLLDDV FEITAVDPDG KKFDRVSRIQ
AKSDNYDMSL LLDVNVELYA LQKAQKFTLV LTKSIALDAS VGADAAWRSD AGPTLADKYE
YVMYGRVFKF EDISTARIWG VMSNGSDVVV LLPHLKALAG NGKSRGPTKG KTGYTFDERM
LYHRDPEDDH PEQPARIEGI LQLFQELGLL ERCIHIAAGK LPTEALQAVH SQELLTFIDQ
LPVEVVKEMD SVYLCPESEI AAKAAVTCTT KIARDIAMGK IGNGFALAMG FCIFNNVAVA
AKELQRLGLA RKIIILDWDI HYGNGTQKIF ASDPDVLFIS IHRYDDGKFY PSDVEGSPTY
VGEASALGSS VNIGWNGPGV TDADYAAAFS RIVMPIAAEF RPDFVFVSAG FDAAQDDPIG
ECLVTPNGFA QMTHQLMSLA AGKVLLVLEG GYNVPVISNC AVSCLKTLLG DPIPYVNTQS
KATVPSEQAS KAISATIKAQ SAYWKSLYPK HHQLRDDFGG ITTLQRMSVN RVFTFGTVYN
SASESNIANL QNSMLHQPFQ GYIKEALRDN WAVIDLHYPA KEWTLKQTQT GSPKDLTLLN
ELMLYIWDHF LVLSESPDIF FVSSGLPSYA VCHLLDQRAV QHRVKGVVVI SPTLYLPVAS
SDRSEWYGSN SLVIVPTKRP EGTPIATNPS FGRCVSAGSE DPAEIATIVA QSQNRVFSFI
EERTRGAC
//
