ID A0A2H9ZRQ3_9ASPA Unreviewed; 444 AA.
AC A0A2H9ZRQ3;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Protein fizzy-like 2 {ECO:0000313|EMBL:PKA45967.1};
GN Name=FZR2 {ECO:0000313|EMBL:PKA45967.1};
GN ORFNames=AXF42_Ash019728 {ECO:0000313|EMBL:PKA45967.1};
OS Apostasia shenzhenica.
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Asparagales; Orchidaceae;
OC Apostasioideae; Apostasia.
OX NCBI_TaxID=1088818 {ECO:0000313|EMBL:PKA45967.1, ECO:0000313|Proteomes:UP000236161};
RN [1] {ECO:0000313|EMBL:PKA45967.1, ECO:0000313|Proteomes:UP000236161}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Shenzhen {ECO:0000313|Proteomes:UP000236161};
RC TISSUE=Stem {ECO:0000313|EMBL:PKA45967.1};
RX PubMed=28902843; DOI=10.1038/nature23897;
RA Zhang G.Q., Liu K.W., Li Z., Lohaus R., Hsiao Y.Y., Niu S.C., Wang J.Y.,
RA Lin Y.C., Xu Q., Chen L.J., Yoshida K., Fujiwara S., Wang Z.W., Zhang Y.Q.,
RA Mitsuda N., Wang M., Liu G.H., Pecoraro L., Huang H.X., Xiao X.J., Lin M.,
RA Wu X.Y., Wu W.L., Chen Y.Y., Chang S.B., Sakamoto S., Ohme-Takagi M.,
RA Yagi M., Zeng S.J., Shen C.Y., Yeh C.M., Luo Y.B., Tsai W.C.,
RA Van de Peer Y., Liu Z.J.;
RT "The Apostasia genome and the evolution of orchids.";
RL Nature 549:379-383(2017).
CC -!- FUNCTION: Component of the anaphase promoting complex/cyclosome
CC (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex
CC that controls progression through mitosis and the G1 phase of the cell
CC cycle. {ECO:0000256|ARBA:ARBA00023425}.
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DR EMBL; KZ454627; PKA45967.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2H9ZRQ3; -.
DR STRING; 1088818.A0A2H9ZRQ3; -.
DR OrthoDB; 20041at2759; -.
DR Proteomes; UP000236161; Unassembled WGS sequence.
DR GO; GO:0043229; C:intracellular organelle; IEA:UniProt.
DR GO; GO:0010997; F:anaphase-promoting complex binding; IEA:InterPro.
DR GO; GO:0097027; F:ubiquitin-protein transferase activator activity; IEA:InterPro.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR033010; Cdc20/Fizzy.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR019775; WD40_repeat_CS.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR19918; CELL DIVISION CYCLE 20 CDC20 FIZZY -RELATED; 1.
DR PANTHER; PTHR19918:SF8; CELL DIVISION CYCLE 20.1, COFACTOR OF APC COMPLEX-RELATED; 1.
DR Pfam; PF00400; WD40; 3.
DR SMART; SM00320; WD40; 4.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS00678; WD_REPEATS_1; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 2.
DR PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000236161};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}.
FT REPEAT 195..236
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 279..320
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REGION 1..25
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 110..141
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 118..138
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 444 AA; 49321 MW; B15521DD796CE660 CRC64;
MDAGSVNSSF SSSYEKTLQR SRQPLEQVVS KVYIPSLRSS SSNPSSYRQS GDRFIPDRSA
MDFDVAHYLL TQTRKEKENN GVLSPAKEAY RKLLAETLLN NRTRILAFNR KPPSQLHGET
LPATSDSVAS SQRTKKSRRY IPQSAERTLD APDIVDDFYL NLLDWGSKNV LSIALGNTVY
LWNATNGSTS ELVTVEDDLG PVTSVSWAPD GQHVSIGLNN SHIQLWDSSS NRLLRILKGV
HRSRVGSLSW NNNILTTGGM EGKIINNDVR IRNHVVQIYR GHQEEVCGLK WSSSGQLLAS
GGNDNLMHIW DISMAGSSST AAPNQNQWLH RFEDHNAAVK ALAWCPFQSN LLASGGGGTD
QCIKLWNTQT GACLNSVDTG SQVCGLLWNK NERELLSSHG FTQNQLTLWK YPSMVKMAEL
SGHTSRVLFM AQVKFFVLFL TLEM
//
