ID A0A2I0ADV9_9ASPA Unreviewed; 1297 AA.
AC A0A2I0ADV9;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=RNA-directed DNA polymerase like {ECO:0000313|EMBL:PKA53732.1};
GN ORFNames=AXF42_Ash021027 {ECO:0000313|EMBL:PKA53732.1};
OS Apostasia shenzhenica.
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Asparagales; Orchidaceae;
OC Apostasioideae; Apostasia.
OX NCBI_TaxID=1088818 {ECO:0000313|EMBL:PKA53732.1, ECO:0000313|Proteomes:UP000236161};
RN [1] {ECO:0000313|EMBL:PKA53732.1, ECO:0000313|Proteomes:UP000236161}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Shenzhen {ECO:0000313|Proteomes:UP000236161};
RC TISSUE=Stem {ECO:0000313|EMBL:PKA53732.1};
RX PubMed=28902843; DOI=10.1038/nature23897;
RA Zhang G.Q., Liu K.W., Li Z., Lohaus R., Hsiao Y.Y., Niu S.C., Wang J.Y.,
RA Lin Y.C., Xu Q., Chen L.J., Yoshida K., Fujiwara S., Wang Z.W., Zhang Y.Q.,
RA Mitsuda N., Wang M., Liu G.H., Pecoraro L., Huang H.X., Xiao X.J., Lin M.,
RA Wu X.Y., Wu W.L., Chen Y.Y., Chang S.B., Sakamoto S., Ohme-Takagi M.,
RA Yagi M., Zeng S.J., Shen C.Y., Yeh C.M., Luo Y.B., Tsai W.C.,
RA Van de Peer Y., Liu Z.J.;
RT "The Apostasia genome and the evolution of orchids.";
RL Nature 549:379-383(2017).
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DR EMBL; KZ451991; PKA53732.1; -; Genomic_DNA.
DR OrthoDB; 953332at2759; -.
DR Proteomes; UP000236161; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0003964; F:RNA-directed DNA polymerase activity; IEA:UniProtKB-KW.
DR GO; GO:0004523; F:RNA-DNA hybrid ribonuclease activity; IEA:InterPro.
DR CDD; cd09279; RNase_HI_like; 1.
DR CDD; cd01647; RT_LTR; 1.
DR Gene3D; 3.30.70.270; -; 2.
DR Gene3D; 3.10.10.10; HIV Type 1 Reverse Transcriptase, subunit A, domain 1; 1.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR005162; Retrotrans_gag_dom.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR002156; RNaseH_domain.
DR InterPro; IPR036397; RNaseH_sf.
DR InterPro; IPR000477; RT_dom.
DR InterPro; IPR041577; RT_RNaseH_2.
DR PANTHER; PTHR24559:SF437; RIBONUCLEASE H; 1.
DR PANTHER; PTHR24559; TRANSPOSON TY3-I GAG-POL POLYPROTEIN; 1.
DR Pfam; PF03732; Retrotrans_gag; 1.
DR Pfam; PF17919; RT_RNaseH_2; 1.
DR Pfam; PF00078; RVT_1; 1.
DR Pfam; PF13456; RVT_3; 1.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR SUPFAM; SSF53098; Ribonuclease H-like; 1.
DR PROSITE; PS50879; RNASE_H_1; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleotidyltransferase {ECO:0000313|EMBL:PKA53732.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000236161};
KW RNA-directed DNA polymerase {ECO:0000313|EMBL:PKA53732.1};
KW Transferase {ECO:0000313|EMBL:PKA53732.1}.
FT DOMAIN 1144..1273
FT /note="RNase H type-1"
FT /evidence="ECO:0000259|PROSITE:PS50879"
FT REGION 1..31
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 67..103
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 289..340
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 422..446
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 67..81
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 295..312
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 313..337
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1297 AA; 146128 MW; 673437445947E856 CRC64;
MEHARDENAP PPPGEQQATR LPQDDATRDD RQLQTLTNTV ATLTRTMNTF LANLPALLQQ
PRHLPLALPL EAPPPQPGTE HVELPPEETS THAAAESRPE VYSPAPPADT IFSPAIMAAP
APRAYKTPRV SDYNGLTDPA QHVKRFENTL ATSDPVSDAY KCRFFRNTLT GLALDWLDEI
PHGSVQNFQQ FSEQFRTRFG TSKTTSRTIH ELWQIRQASD ESLHNYVDRF SKMNAETKDT
TDDRSTMIFV HSILPGELYD SFVDNMPKTL MEARARAEKR IHLEDAKALK AKARQEATSP
QTKQGETPKT DSNTPRRSFR DRNYSPTQGK RKFGDESPRP ATPVYIVEEI FSILSDKCFI
KNRGERQPPQ PGEDPTKFCK FHQRYGYLLF ECRSSRALVN EYIENDYLTG YRKIEGPLPK
AARPLFPSDA PKGAPSSTPT TPKSDGKKVV LSIFGYHSSL RTQRHQEVCT VKLPPLLPDI
TFTAGDLPRG GINRDDPIVV IAEIGACDVH RTLVDTGNLV DILYLCAFNE MAVGPYKPLP
PSMTISSFSG DIYRPAGYTT LRVALEEGPR RMEKEIDFII MDAPSGYNAI LGRPAITAFQ
MVASTYHLCV KFLTPFGVAT IRGARAGASK CFEINARLHT DYMDPRDHAL PPVEQNDRVT
VADGKTVLIS KNFPDNEKPA LTGLLFEYFD VFAWEPCDMP GIDRAVAEHR LSLKPGVAPV
RQKKRTFGGE KQCAIREEVK KLLAAGFIRE ITYPSWLANV VVVKKNSGKW RMCVDFTDLN
KACPKDFYPL PKIDRLVDSS AGYSVMSFVD AFSGYHQIRM AEDDEEHTSF ITDQGTFCYK
VMPFGLKNAG ATYQCMIDTV FKNQRGRNIE AYVDDVLIKS VCAKQHLEDL RETLDTCRTY
NKLNPMKSIF GSSYGKFLGH MVSARGIEAN PEKIQAIQDM KPPQTIQDIQ KLNGRVTALS
RFISKSGERC LPFFKILRGE RQAWNEDCTK AFQSLKEYLL SPSLLSTPVQ DEDLFLYLST
TDNSVSAVIV REEAARQHPI HYISHILHGA EVRYPPLKKL SFALISAARR LRHYFQAHPI
KVMTDQPLRR ILHSPEISGR LQKWVVELSE FDIDFLPRTA TKSQALADFI AELTTTEQPE
PRKRPQPWTL HVDGASGERI HGVGIVLTSP WGIRLQRSGK IHFPVTNNQA EYEALIVGLK
FAKGLGARQL DVYSDSKLMV NQLTGSYQTK DEVLKRYFQL TKTLLQQFAQ TSLFHIPREM
NSLADELAKE ENDNALDILF PAFEDPQIFD IESNPES
//
