ID A0A2I0AHW1_9ASPA Unreviewed; 610 AA.
AC A0A2I0AHW1;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 24-JAN-2024, entry version 19.
DE SubName: Full=ATP-dependent zinc metalloprotease FTSH 6, chloroplastic {ECO:0000313|EMBL:PKA55130.1};
DE EC=3.4.24.- {ECO:0000313|EMBL:PKA55130.1};
GN Name=FTSH6 {ECO:0000313|EMBL:PKA55130.1};
GN ORFNames=AXF42_Ash003767 {ECO:0000313|EMBL:PKA55130.1};
OS Apostasia shenzhenica.
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Asparagales; Orchidaceae;
OC Apostasioideae; Apostasia.
OX NCBI_TaxID=1088818 {ECO:0000313|EMBL:PKA55130.1, ECO:0000313|Proteomes:UP000236161};
RN [1] {ECO:0000313|EMBL:PKA55130.1, ECO:0000313|Proteomes:UP000236161}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Shenzhen {ECO:0000313|Proteomes:UP000236161};
RC TISSUE=Stem {ECO:0000313|EMBL:PKA55130.1};
RX PubMed=28902843; DOI=10.1038/nature23897;
RA Zhang G.Q., Liu K.W., Li Z., Lohaus R., Hsiao Y.Y., Niu S.C., Wang J.Y.,
RA Lin Y.C., Xu Q., Chen L.J., Yoshida K., Fujiwara S., Wang Z.W., Zhang Y.Q.,
RA Mitsuda N., Wang M., Liu G.H., Pecoraro L., Huang H.X., Xiao X.J., Lin M.,
RA Wu X.Y., Wu W.L., Chen Y.Y., Chang S.B., Sakamoto S., Ohme-Takagi M.,
RA Yagi M., Zeng S.J., Shen C.Y., Yeh C.M., Luo Y.B., Tsai W.C.,
RA Van de Peer Y., Liu Z.J.;
RT "The Apostasia genome and the evolution of orchids.";
RL Nature 549:379-383(2017).
CC -!- SIMILARITY: Belongs to the AAA ATPase family.
CC {ECO:0000256|RuleBase:RU003651}.
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DR EMBL; KZ451980; PKA55130.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2I0AHW1; -.
DR STRING; 1088818.A0A2I0AHW1; -.
DR OrthoDB; 1116483at2759; -.
DR Proteomes; UP000236161; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0004176; F:ATP-dependent peptidase activity; IEA:InterPro.
DR GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd19501; RecA-like_FtsH; 1.
DR Gene3D; 1.10.8.60; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR041569; AAA_lid_3.
DR InterPro; IPR003959; ATPase_AAA_core.
DR InterPro; IPR003960; ATPase_AAA_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR011546; Pept_M41_FtsH_extracell.
DR PANTHER; PTHR23076:SF110; INACTIVE ATP-DEPENDENT ZINC METALLOPROTEASE FTSHI 3, CHLOROPLASTIC-RELATED; 1.
DR PANTHER; PTHR23076; METALLOPROTEASE M41 FTSH; 1.
DR Pfam; PF00004; AAA; 1.
DR Pfam; PF17862; AAA_lid_3; 1.
DR Pfam; PF06480; FtsH_ext; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00674; AAA; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|RuleBase:RU003651};
KW Hydrolase {ECO:0000313|EMBL:PKA55130.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Metalloprotease {ECO:0000313|EMBL:PKA55130.1};
KW Nucleotide-binding {ECO:0000256|RuleBase:RU003651};
KW Protease {ECO:0000313|EMBL:PKA55130.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000236161};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 135..156
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 354..490
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
SQ SEQUENCE 610 AA; 67650 MW; 8FF2A3904A335B8C CRC64;
MIPQSCSINR PLLLFNGREQ RAQALKYFPL RKISGDVSSS LSLSFRCSPA VSLSVFQCKN
KLRSRCNRKV FANMSRADEE KPISAGIGDK PLPRKRFSLR LRARFRLLSA KMRKISIRGL
VEEAELALRK NSKKATLSTL LSIAMAFCFL IMKLTAVPAS KVVPYSDLIS NLQSGGVSKV
LFEEGSRRIF YNTIPDNQKS LERKVDVLLE IEENQKSSLP THQANPASYY SRWRVGSVPK
WQYVTRKIDH DENFLLGLMR EKGTTYSSAP QSALMSLRNV IITIISLWIP LTPLMWLLYR
QLSSANSPAR KRRPTNQTVD FDDVEGVDAA KEELMEIVSC LQGSINYSKL GAKLPRGVLL
IGPPGTGKTL LARAVAGEVG VPFFSVSASE FVELFVGRGA ARIRDLFNTA KRCTPAIVFI
DELDAVGGRR GKSFNDERDQ TLNQLLTEMD GFESDMKVIV IAATNRPEAL DPALCRPGRF
SRKVHVGEPD LEGRKRILAV HLRGIPLEEE SQLICNLVAS LTPGFVGADL ANVVNEAALL
AARRGGEVVC REDIMEAIER AKFGINDKQS GSMALTKGIN KWLPWMPAIW GKDAAREAGM
NSLMGYQTLS
//
