ID A0A2I0B1F1_9ASPA Unreviewed; 589 AA.
AC A0A2I0B1F1;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 24-JAN-2024, entry version 18.
DE SubName: Full=K(+) efflux antiporter 5 {ECO:0000313|EMBL:PKA61623.1};
GN Name=KEA5 {ECO:0000313|EMBL:PKA61623.1};
GN ORFNames=AXF42_Ash018604 {ECO:0000313|EMBL:PKA61623.1};
OS Apostasia shenzhenica.
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Asparagales; Orchidaceae;
OC Apostasioideae; Apostasia.
OX NCBI_TaxID=1088818 {ECO:0000313|EMBL:PKA61623.1, ECO:0000313|Proteomes:UP000236161};
RN [1] {ECO:0000313|EMBL:PKA61623.1, ECO:0000313|Proteomes:UP000236161}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Shenzhen {ECO:0000313|Proteomes:UP000236161};
RC TISSUE=Stem {ECO:0000313|EMBL:PKA61623.1};
RX PubMed=28902843; DOI=10.1038/nature23897;
RA Zhang G.Q., Liu K.W., Li Z., Lohaus R., Hsiao Y.Y., Niu S.C., Wang J.Y.,
RA Lin Y.C., Xu Q., Chen L.J., Yoshida K., Fujiwara S., Wang Z.W., Zhang Y.Q.,
RA Mitsuda N., Wang M., Liu G.H., Pecoraro L., Huang H.X., Xiao X.J., Lin M.,
RA Wu X.Y., Wu W.L., Chen Y.Y., Chang S.B., Sakamoto S., Ohme-Takagi M.,
RA Yagi M., Zeng S.J., Shen C.Y., Yeh C.M., Luo Y.B., Tsai W.C.,
RA Van de Peer Y., Liu Z.J.;
RT "The Apostasia genome and the evolution of orchids.";
RL Nature 549:379-383(2017).
CC -!- FUNCTION: May function as sodium-coupled metabolite transporter across
CC the chloroplast envelope. {ECO:0000256|ARBA:ARBA00003198}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}. Plastid,
CC chloroplast envelope {ECO:0000256|ARBA:ARBA00004119}.
CC -!- SIMILARITY: Belongs to the bile acid:sodium symporter (BASS) (TC
CC 2.A.28) family. {ECO:0000256|ARBA:ARBA00006528}.
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DR EMBL; KZ451927; PKA61623.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2I0B1F1; -.
DR OrthoDB; 399505at2759; -.
DR Proteomes; UP000236161; Unassembled WGS sequence.
DR GO; GO:0009941; C:chloroplast envelope; IEA:UniProtKB-SubCell.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015386; F:potassium:proton antiporter activity; IEA:InterPro.
DR Gene3D; 1.20.1530.20; -; 1.
DR InterPro; IPR006153; Cation/H_exchanger.
DR InterPro; IPR045158; KEA4/5/6-like.
DR InterPro; IPR038770; Na+/solute_symporter_sf.
DR PANTHER; PTHR16254:SF20; K(+) EFFLUX ANTIPORTER 5; 1.
DR PANTHER; PTHR16254; POTASSIUM/PROTON ANTIPORTER-RELATED; 1.
DR Pfam; PF00999; Na_H_Exchanger; 1.
PE 3: Inferred from homology;
KW Antiport {ECO:0000256|ARBA:ARBA00022449};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000236161};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 12..33
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 174..202
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 222..241
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 253..275
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 281..300
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 312..334
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 340..364
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 438..458
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 464..482
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 494..512
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 524..543
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 175..544
FT /note="Cation/H+ exchanger"
FT /evidence="ECO:0000259|Pfam:PF00999"
SQ SEQUENCE 589 AA; 63245 MW; D2ED73ECE1DC9979 CRC64;
MAAGTGAASA GIAPTRVMLV LVMVCLALLS PLARPRPDQE MRERFYGALA TTAPRNNSGD
GSIADIFDRV LEKEFSSERD EKEGHDSSSF NSTVADHQGV VETVAVITHD KTKKNDTLVA
NTTKPFQIQD VFSLENEDSD GIQLIDQKDN IFVMSNRKSK YPVLQVDLRL ISDLVVVIVS
AAIGGVTSCC LGQPVIVGYL FAGSIIGPGG LNFISEIVQV ETTAHFGVVF LLFALGLEFS
LAKIKVVGPV AVLGGLVQII ILMLVCGISS LLCGAKLSDG VFVGSFLSMS STAVVSKFIV
ERSSTNSLHG QVTIGTLILQ DCAVGLLFAL LPVLGGNSGL IQGIVSIAKL VLMLSVFISI
AYVLSVSFLP QFLKLMVQLS SQTNELYQLA SVAFCLLFAW GSDKLGLSLE LGSFVAGVMV
STTDFAQHTL EQVEPIRNLF AALFLASIGM LIHVQFLWNH VDILLASVML VVIVKTLIIT
GVIKSFGYSF RTSFAVGLSL AQIGEFAFVL LSRASNLHLV EGKMYLLLLG TTAFSLITTP
LMFKTIPAVL HLGNLMRWFP SVSMQSETDG FDKVQSEIET LFNDIVRGI
//
