ID A0A2I0B5X8_9ASPA Unreviewed; 259 AA.
AC A0A2I0B5X8;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Methyl-CpG-binding domain-containing protein 11 {ECO:0000313|EMBL:PKA63190.1};
GN Name=MBD11 {ECO:0000313|EMBL:PKA63190.1};
GN ORFNames=AXF42_Ash020563 {ECO:0000313|EMBL:PKA63190.1};
OS Apostasia shenzhenica.
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Asparagales; Orchidaceae;
OC Apostasioideae; Apostasia.
OX NCBI_TaxID=1088818 {ECO:0000313|EMBL:PKA63190.1, ECO:0000313|Proteomes:UP000236161};
RN [1] {ECO:0000313|EMBL:PKA63190.1, ECO:0000313|Proteomes:UP000236161}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Shenzhen {ECO:0000313|Proteomes:UP000236161};
RC TISSUE=Stem {ECO:0000313|EMBL:PKA63190.1};
RX PubMed=28902843; DOI=10.1038/nature23897;
RA Zhang G.Q., Liu K.W., Li Z., Lohaus R., Hsiao Y.Y., Niu S.C., Wang J.Y.,
RA Lin Y.C., Xu Q., Chen L.J., Yoshida K., Fujiwara S., Wang Z.W., Zhang Y.Q.,
RA Mitsuda N., Wang M., Liu G.H., Pecoraro L., Huang H.X., Xiao X.J., Lin M.,
RA Wu X.Y., Wu W.L., Chen Y.Y., Chang S.B., Sakamoto S., Ohme-Takagi M.,
RA Yagi M., Zeng S.J., Shen C.Y., Yeh C.M., Luo Y.B., Tsai W.C.,
RA Van de Peer Y., Liu Z.J.;
RT "The Apostasia genome and the evolution of orchids.";
RL Nature 549:379-383(2017).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; KZ451910; PKA63190.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2I0B5X8; -.
DR STRING; 1088818.A0A2I0B5X8; -.
DR OrthoDB; 622866at2759; -.
DR Proteomes; UP000236161; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR CDD; cd00122; MBD; 1.
DR InterPro; IPR016177; DNA-bd_dom_sf.
DR InterPro; IPR039622; MBD10/11.
DR InterPro; IPR001739; Methyl_CpG_DNA-bd.
DR PANTHER; PTHR33729; METHYL-CPG BINDING DOMAIN CONTAINING PROTEIN, EXPRESSED; 1.
DR PANTHER; PTHR33729:SF6; METHYL-CPG-BINDING DOMAIN-CONTAINING PROTEIN 10; 1.
DR Pfam; PF01429; MBD; 1.
DR SMART; SM00391; MBD; 1.
DR SUPFAM; SSF54171; DNA-binding domain; 1.
DR PROSITE; PS50982; MBD; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000236161};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 17..87
FT /note="MBD"
FT /evidence="ECO:0000259|PROSITE:PS50982"
FT REGION 72..249
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 104..129
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 144..169
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 170..184
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 206..237
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 259 AA; 28309 MW; 668C21F2B79D12AC CRC64;
MASDDGGSGG GVDRWEEPEI VPVELPAPLG WRKTFTPKKS GIPKKAEIVF IAPTGEEITT
RKQLEQYLKS HPGTPALHEF DWSTSVKFPR RSARISEKAK AVSSLEPQPK KKRSRRSTSG
PKKAGDVETE TVLELLPENQ KGGVQDESIK EEKNNAESDE VEDEGTAKKS QGDSQIAASE
KTENQGEGET SDQDKQVGRS QIDVSQERQP EGDKHKAEKQ TSDAGEGIAD GRDDEQKQNN
FNQPGLIDSK QCLAPTLSC
//
