ID A0A2I0B8V2_9ASPA Unreviewed; 641 AA.
AC A0A2I0B8V2;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=DNA mismatch repair protein MSH1, mitochondrial {ECO:0000313|EMBL:PKA64181.1};
GN Name=MSH1 {ECO:0000313|EMBL:PKA64181.1};
GN ORFNames=AXF42_Ash005194 {ECO:0000313|EMBL:PKA64181.1};
OS Apostasia shenzhenica.
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Asparagales; Orchidaceae;
OC Apostasioideae; Apostasia.
OX NCBI_TaxID=1088818 {ECO:0000313|EMBL:PKA64181.1, ECO:0000313|Proteomes:UP000236161};
RN [1] {ECO:0000313|EMBL:PKA64181.1, ECO:0000313|Proteomes:UP000236161}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Shenzhen {ECO:0000313|Proteomes:UP000236161};
RC TISSUE=Stem {ECO:0000313|EMBL:PKA64181.1};
RX PubMed=28902843; DOI=10.1038/nature23897;
RA Zhang G.Q., Liu K.W., Li Z., Lohaus R., Hsiao Y.Y., Niu S.C., Wang J.Y.,
RA Lin Y.C., Xu Q., Chen L.J., Yoshida K., Fujiwara S., Wang Z.W., Zhang Y.Q.,
RA Mitsuda N., Wang M., Liu G.H., Pecoraro L., Huang H.X., Xiao X.J., Lin M.,
RA Wu X.Y., Wu W.L., Chen Y.Y., Chang S.B., Sakamoto S., Ohme-Takagi M.,
RA Yagi M., Zeng S.J., Shen C.Y., Yeh C.M., Luo Y.B., Tsai W.C.,
RA Van de Peer Y., Liu Z.J.;
RT "The Apostasia genome and the evolution of orchids.";
RL Nature 549:379-383(2017).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KZ451906; PKA64181.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2I0B8V2; -.
DR STRING; 1088818.A0A2I0B8V2; -.
DR OrthoDB; 5490617at2759; -.
DR Proteomes; UP000236161; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0004519; F:endonuclease activity; IEA:InterPro.
DR GO; GO:0030983; F:mismatched DNA binding; IEA:InterPro.
DR GO; GO:0006298; P:mismatch repair; IEA:InterPro.
DR GO; GO:0045910; P:negative regulation of DNA recombination; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR000432; DNA_mismatch_repair_MutS_C.
DR InterPro; IPR007696; DNA_mismatch_repair_MutS_core.
DR InterPro; IPR036187; DNA_mismatch_repair_MutS_sf.
DR InterPro; IPR005747; MutS2.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR48378:SF1; DNA MISMATCH REPAIR PROTEINS MUTS FAMILY DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR48378; DNA MISMATCH REPAIR PROTEINS MUTS FAMILY DOMAIN-CONTAINING PROTEIN-RELATED; 1.
DR Pfam; PF00488; MutS_V; 1.
DR PIRSF; PIRSF005814; MutS_YshD; 1.
DR SMART; SM00534; MUTSac; 1.
DR SMART; SM00533; MUTSd; 1.
DR SUPFAM; SSF48334; DNA repair protein MutS, domain III; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00486; DNA_MISMATCH_REPAIR_2; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000236161}.
FT DOMAIN 542..558
FT /note="DNA mismatch repair proteins mutS family"
FT /evidence="ECO:0000259|PROSITE:PS00486"
FT COILED 206..233
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 286..313
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 641 AA; 70642 MW; FCCC86B8B2F02377 CRC64;
MFCSEISSAS GSNLFAVACP KTYARRWNPS AGLQQLHIAS ADGRKPKSSA ISDSLRLLEW
DKVCDMVSSF ACTPLGREAA KAQLWATTDL SFEESKKRLE ETSAAIELLN YGAGGVDFAG
IDVMTVKSAI DQASRGFHMD GLEAMAVVSL IEFAGNLKTM VEAAVNDDTD CYNRFMPLAQ
MIMNTHICNA LVKMVRQVID EDGTVKDNAS SELKQHRDQV HSLERKLYHL MDKLARNDRI
ETSSMEICNI NGRWCLKAAS SELGKLDGLL LPSGSGHLSL FEPVAAVPLN DELQQARALV
AKAEEDVLSL LTDKMRAELG SIQNLLEMMI QLDVVVARAR YSIEYGATYP KIFWPGVIKS
HNVEGNSLLK RTSNKASLSH HLNEWKLYMR KAFHPLLLKR YRENLQSARK ALAGAIYEAK
NKRLQGKNIA AESIELLKER VWQLERDPPM PVDFVISIKT SIVVITGPNT GGKTISLKTV
GLASLMSKSG LYVLAAEPVK VPWFDAVYAD IGDEQSLTHS LSTFSGHLRQ ISAIHSSSTG
DSLVLLDEVG AGTNPLEGTA LGMSILESFA EMGAFLSMAT THHGELKTLK YSNHAFENAC
VEFDEESLKP TYRILWGIPG SFECHKYIRE VRTSPSYIVL C
//
