ID A0A2I0CUZ2_9PSED Unreviewed; 369 AA.
AC A0A2I0CUZ2;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 24-JAN-2024, entry version 19.
DE SubName: Full=Phosphohydrolase {ECO:0000313|EMBL:PKF73426.1};
GN ORFNames=CW360_00660 {ECO:0000313|EMBL:PKF73426.1};
OS Pseudomonas pharmacofabricae.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales;
OC Pseudomonadaceae; Pseudomonas.
OX NCBI_TaxID=1905276 {ECO:0000313|EMBL:PKF73426.1, ECO:0000313|Proteomes:UP000242861};
RN [1] {ECO:0000313|Proteomes:UP000242861}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ZYSR67-Z {ECO:0000313|Proteomes:UP000242861};
RA Yu X.-Y.;
RL Submitted (DEC-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PKF73426.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; PIYS01000001; PKF73426.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2I0CUZ2; -.
DR Proteomes; UP000242861; Unassembled WGS sequence.
DR GO; GO:0008081; F:phosphoric diester hydrolase activity; IEA:UniProt.
DR GO; GO:0004672; F:protein kinase activity; IEA:UniProt.
DR GO; GO:0000160; P:phosphorelay signal transduction system; IEA:UniProtKB-KW.
DR CDD; cd00077; HDc; 1.
DR CDD; cd00088; HPT; 1.
DR Gene3D; 1.20.120.160; HPT domain; 1.
DR Gene3D; 1.10.3210.10; Hypothetical protein af1432; 1.
DR InterPro; IPR003607; HD/PDEase_dom.
DR InterPro; IPR037522; HD_GYP_dom.
DR InterPro; IPR036641; HPT_dom_sf.
DR InterPro; IPR008207; Sig_transdc_His_kin_Hpt_dom.
DR PANTHER; PTHR43155:SF2; CYCLIC DI-GMP PHOSPHODIESTERASE PA4108; 1.
DR PANTHER; PTHR43155; CYCLIC DI-GMP PHOSPHODIESTERASE PA4108-RELATED; 1.
DR Pfam; PF13487; HD_5; 1.
DR Pfam; PF01627; Hpt; 1.
DR SMART; SM00073; HPT; 1.
DR SUPFAM; SSF109604; HD-domain/PDEase-like; 1.
DR SUPFAM; SSF47226; Histidine-containing phosphotransfer domain, HPT domain; 1.
DR PROSITE; PS51832; HD_GYP; 1.
DR PROSITE; PS50894; HPT; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000313|EMBL:PKF73426.1};
KW Phosphoprotein {ECO:0000256|PROSITE-ProRule:PRU00110};
KW Reference proteome {ECO:0000313|Proteomes:UP000242861};
KW Two-component regulatory system {ECO:0000256|ARBA:ARBA00023012}.
FT DOMAIN 2..106
FT /note="HPt"
FT /evidence="ECO:0000259|PROSITE:PS50894"
FT DOMAIN 170..369
FT /note="HD-GYP"
FT /evidence="ECO:0000259|PROSITE:PS51832"
FT MOD_RES 49
FT /note="Phosphohistidine"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00110"
SQ SEQUENCE 369 AA; 41629 MW; 88BEB549F86F8A1A CRC64;
MNSPVDSDLL QDLRLDAEEQ LPRCEQLLIE LEQHADDSER LAELFRLLHS LKGNIGMVGL
HALLPLPQAM EDILAALRSR QLRFDSLLGD ILLLSFDRLR QHLQAVYAGA LDYQPDTDCA
QLAIALHELA GTATAQQATA RQRLLLQLAP GSALQPNATS ESPPDCARLL ERYDIPADAD
VQFCLTLMQA IEQRSRYWQG RGLRLLHLTL AINQQGGRVV DPAQLAVATC LHDLGMAFLP
LHVLHKESRL SREEVQHIRS HPRLGHDLLR RLERWEDAAE IVLHHQEHAD GQGYPRGLRE
VEIHPGALIL AIADTFDART HERAHQTLSK RPRLRAILEI NNLAGRQFSA HWVEVFNHTL
QQQPQLAHL
//
