ID   A0A2I0FS31_9GAMM        Unreviewed;       438 AA.
AC   A0A2I0FS31;
DT   28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT   28-FEB-2018, sequence version 1.
DT   24-JAN-2024, entry version 16.
DE   RecName: Full=Permease IIC component {ECO:0000256|PIRNR:PIRNR006351};
GN   ORFNames=CIG19_17775 {ECO:0000313|EMBL:PKH20481.1};
OS   Enterobacterales bacterium CwR94.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales.
OX   NCBI_TaxID=2025587 {ECO:0000313|EMBL:PKH20481.1, ECO:0000313|Proteomes:UP000237543};
RN   [1] {ECO:0000313|EMBL:PKH20481.1, ECO:0000313|Proteomes:UP000237543}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CwR94 {ECO:0000313|EMBL:PKH20481.1,
RC   ECO:0000313|Proteomes:UP000237543};
RA   de Groot N.N.;
RL   Submitted (AUG-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: The phosphoenolpyruvate-dependent sugar phosphotransferase
CC       system (PTS), a major carbohydrate active -transport system, catalyzes
CC       the phosphorylation of incoming sugar substrates concomitant with their
CC       translocation across the cell membrane.
CC       {ECO:0000256|PIRNR:PIRNR006351}.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PKH20481.1}.
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DR   EMBL; NVXY01000014; PKH20481.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2I0FS31; -.
DR   OrthoDB; 5843984at2; -.
DR   Proteomes; UP000237543; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-UniRule.
DR   GO; GO:0008982; F:protein-N(PI)-phosphohistidine-sugar phosphotransferase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0009401; P:phosphoenolpyruvate-dependent sugar phosphotransferase system; IEA:InterPro.
DR   InterPro; IPR003352; PTS_EIIC.
DR   InterPro; IPR004501; PTS_EIIC_3.
DR   InterPro; IPR004796; PTS_IIC_cello.
DR   NCBIfam; TIGR00410; lacE; 1.
DR   PANTHER; PTHR33989; -; 1.
DR   PANTHER; PTHR33989:SF4; PTS SYSTEM N,N'-DIACETYLCHITOBIOSE-SPECIFIC EIIC COMPONENT; 1.
DR   Pfam; PF02378; PTS_EIIC; 1.
DR   PIRSF; PIRSF006351; PTS_EIIC-Cellobiose; 1.
DR   PROSITE; PS51105; PTS_EIIC_TYPE_3; 1.
PE   4: Predicted;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475,
KW   ECO:0000256|PIRNR:PIRNR006351};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PIRNR:PIRNR006351};
KW   Reference proteome {ECO:0000313|Proteomes:UP000237543};
KW   Sugar transport {ECO:0000256|ARBA:ARBA00022597,
KW   ECO:0000256|PIRNR:PIRNR006351};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius};
KW   Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|PIRNR:PIRNR006351}.
FT   TRANSMEM        35..53
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        86..104
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        111..131
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        143..161
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        182..202
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        208..225
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        232..260
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        285..306
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        343..362
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        395..414
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          12..413
FT                   /note="PTS EIIC type-3"
FT                   /evidence="ECO:0000259|PROSITE:PS51105"
SQ   SEQUENCE   438 AA;  47983 MW;  86E8DEA392D1ECEF CRC64;
     MSTLATTLFN VIENRISPIA AKLSSQRHVV AIKDGFIASM PFLIVGSFML LFSHPPFSAN
     SEWAFAQWWL GIVAQYNDQL MLPYNMTMGI MAVYITAAIA YNLAQSYKMN GLMAALLALM
     SFLVVAAPQT NGTLSVSSLG GEGIFTAILI AIYTTEVMHI LQKYRIGISL PEQVPPKIRQ
     SFDLLIPILV IFLTLYPLNL FFQSHFGMLI PQAIMAMFSP IISAADSLPA VLLAVLLCHL
     LWFAGIHGAA IVGGILQAFW LSNLGINQEA LNSGGEVSKI FIEPFWQFFI TVGGSGATMG
     LVLLYLRSRS AHLRSIGKLG LVPGMFNINE PIIFGSPVVM NPLLFIPFIT APMINAVIAW
     TATRTDLVNH VISLAPWTTP GPIGAAWSTG WDWRAVVLVA VLIGLSTLIY YPFFKMYERQ
     LLEQEAEMAA DTFAQEAK
//