ID A0A2I0FZZ5_9GAMM Unreviewed; 364 AA.
AC A0A2I0FZZ5;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE SubName: Full=Sodium-potassium/proton antiporter ChaA {ECO:0000313|EMBL:PKH26464.1};
GN ORFNames=CIG19_01315 {ECO:0000313|EMBL:PKH26464.1};
OS Enterobacterales bacterium CwR94.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales.
OX NCBI_TaxID=2025587 {ECO:0000313|EMBL:PKH26464.1, ECO:0000313|Proteomes:UP000237543};
RN [1] {ECO:0000313|EMBL:PKH26464.1, ECO:0000313|Proteomes:UP000237543}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CwR94 {ECO:0000313|EMBL:PKH26464.1,
RC ECO:0000313|Proteomes:UP000237543};
RA de Groot N.N.;
RL Submitted (AUG-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PKH26464.1}.
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DR EMBL; NVXY01000001; PKH26464.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2I0FZZ5; -.
DR OrthoDB; 9787814at2; -.
DR Proteomes; UP000237543; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR InterPro; IPR004837; NaCa_Exmemb.
DR PANTHER; PTHR37958; SODIUM-POTASSIUM/PROTON ANTIPORTER CHAA; 1.
DR PANTHER; PTHR37958:SF1; SODIUM-POTASSIUM_PROTON ANTIPORTER CHAA; 1.
DR Pfam; PF01699; Na_Ca_ex; 2.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000237543};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..30
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 36..60
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 72..94
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 106..125
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 145..163
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 169..188
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 219..236
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 256..276
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 288..310
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 316..338
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 345..363
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 40..190
FT /note="Sodium/calcium exchanger membrane region"
FT /evidence="ECO:0000259|Pfam:PF01699"
FT DOMAIN 221..362
FT /note="Sodium/calcium exchanger membrane region"
FT /evidence="ECO:0000259|Pfam:PF01699"
SQ SEQUENCE 364 AA; 38862 MW; 424DA859B0334C28 CRC64;
MSAADSTTKT RHTEYSLFLP LIALGVLWFF GSTTQFSALI GINLLALVGI LASAFSVVRH
ADVLAHRLGE PYGSLILSLS VVILEVSLIS ALMATGSAAP ALMRDTLYSI IMIVTTGLVG
FSLLLGGRKF ATQYVNLAGI KQYMIAIFPL AIIVLVFPIA LPGGNFTPVQ ALIAAAISAS
MYGVFLLIQT KTHQSLFVYE HEDDDGDPHH GKPSAHSSGW HAMWLVVHLI AVIVVTKMNA
NPLEGLLTEL DAPKQFTGFL VALLILSPEG LGALRAVLAN QVQRAMNLFF GSVLATISLT
VPAVTIIASL TNQELIFGLE LPHMVVMSSA LVLCHISFST GRTNVLNGAA HLALFIAYLM
TIML
//
