ID A0A2I0G0Z6_9GAMM Unreviewed; 480 AA.
AC A0A2I0G0Z6;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Xanthine dehydrogenase small subunit {ECO:0000313|EMBL:PKH26602.1};
GN Name=xdhA {ECO:0000313|EMBL:PKH26602.1};
GN ORFNames=CIG19_02065 {ECO:0000313|EMBL:PKH26602.1};
OS Enterobacterales bacterium CwR94.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales.
OX NCBI_TaxID=2025587 {ECO:0000313|EMBL:PKH26602.1, ECO:0000313|Proteomes:UP000237543};
RN [1] {ECO:0000313|EMBL:PKH26602.1, ECO:0000313|Proteomes:UP000237543}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CwR94 {ECO:0000313|EMBL:PKH26602.1,
RC ECO:0000313|Proteomes:UP000237543};
RA de Groot N.N.;
RL Submitted (AUG-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PKH26602.1}.
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DR EMBL; NVXY01000001; PKH26602.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2I0G0Z6; -.
DR OrthoDB; 9775084at2; -.
DR Proteomes; UP000237543; Unassembled WGS sequence.
DR GO; GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:InterPro.
DR GO; GO:0071949; F:FAD binding; IEA:InterPro.
DR GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR GO; GO:0004854; F:xanthine dehydrogenase activity; IEA:InterPro.
DR CDD; cd00207; fer2; 1.
DR Gene3D; 3.10.20.30; -; 1.
DR Gene3D; 3.30.465.10; -; 1.
DR Gene3D; 1.10.150.120; [2Fe-2S]-binding domain; 1.
DR Gene3D; 3.30.390.50; CO dehydrogenase flavoprotein, C-terminal domain; 1.
DR Gene3D; 3.30.43.10; Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2; 1.
DR InterPro; IPR002888; 2Fe-2S-bd.
DR InterPro; IPR036884; 2Fe-2S-bd_dom_sf.
DR InterPro; IPR036010; 2Fe-2S_ferredoxin-like_sf.
DR InterPro; IPR001041; 2Fe-2S_ferredoxin-type.
DR InterPro; IPR006058; 2Fe2S_fd_BS.
DR InterPro; IPR016208; Ald_Oxase/xanthine_DH-like.
DR InterPro; IPR012675; Beta-grasp_dom_sf.
DR InterPro; IPR005107; CO_DH_flav_C.
DR InterPro; IPR036683; CO_DH_flav_C_dom_sf.
DR InterPro; IPR016166; FAD-bd_PCMH.
DR InterPro; IPR036318; FAD-bd_PCMH-like_sf.
DR InterPro; IPR016167; FAD-bd_PCMH_sub1.
DR InterPro; IPR016169; FAD-bd_PCMH_sub2.
DR InterPro; IPR002346; Mopterin_DH_FAD-bd.
DR InterPro; IPR012175; Xanth_DH_ssu_bac.
DR InterPro; IPR014307; Xanthine_DH_ssu.
DR NCBIfam; TIGR02963; xanthine_xdhA; 1.
DR PANTHER; PTHR45444:SF3; ALDEHYDE OXIDASE_XANTHINE DEHYDROGENASE, MOLYBDOPTERIN BINDING PROTEIN; 1.
DR PANTHER; PTHR45444; XANTHINE DEHYDROGENASE; 1.
DR Pfam; PF03450; CO_deh_flav_C; 1.
DR Pfam; PF00941; FAD_binding_5; 1.
DR Pfam; PF00111; Fer2; 1.
DR Pfam; PF01799; Fer2_2; 1.
DR PIRSF; PIRSF036557; XdhA_RC; 1.
DR SMART; SM01092; CO_deh_flav_C; 1.
DR SUPFAM; SSF54292; 2Fe-2S ferredoxin-like; 1.
DR SUPFAM; SSF55447; CO dehydrogenase flavoprotein C-terminal domain-like; 1.
DR SUPFAM; SSF47741; CO dehydrogenase ISP C-domain like; 1.
DR SUPFAM; SSF56176; FAD-binding/transporter-associated domain-like; 1.
DR PROSITE; PS00197; 2FE2S_FER_1; 1.
DR PROSITE; PS51085; 2FE2S_FER_2; 1.
DR PROSITE; PS51387; FAD_PCMH; 1.
PE 4: Predicted;
KW FAD {ECO:0000256|ARBA:ARBA00022827};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022827};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000237543}.
FT DOMAIN 1..85
FT /note="2Fe-2S ferredoxin-type"
FT /evidence="ECO:0000259|PROSITE:PS51085"
FT DOMAIN 187..360
FT /note="FAD-binding PCMH-type"
FT /evidence="ECO:0000259|PROSITE:PS51387"
SQ SEQUENCE 480 AA; 52493 MW; F4FC0E64D53054E7 CRC64;
MIQFLYHDRL MTETQCDPNM TVLHWLRRRQ QQTGTKEGCA SGDCGACTVA LGRVVAGRIR
YESANSCLLP ISQLQGCQLL SVDSLKQSSQ LHPVQQSLAD CHASQCGFCT PGFVMSVFTL
AKQEIAPDRH AINEALGGNL CRCTGYRPLV EAAIKVCAVP LNDTFLRNEQ QTVQQLQALA
NPDVQSLNEA GHQLWLPKTV SQLAALYQAN PQAQLIAGGT DLMLQVTQQF RALPALIALH
QIAELQQCSQ SDDHYIIGAA APITDVAHFL QPMLPAFGRL LQRFASQQIR NLGTCGGNIA
NASPIGDIPP LLLALDAWLL VQQGEQLRRV ALADFFLDYR KTQLRPGEFI RTIHIPKPAA
MTQLRAWKVS KRQDDDISTV CGTFNAQFTE GVLRAPRVAF GGMAAIPKRA AGCEAALNGQ
PLNEQTLEVA CAALTQDFQP LSDFRGSSAY RLAVAQNLLR RYFAALQDHS QPLEVSDDVA
//
