ID   A0A2I0G174_9GAMM        Unreviewed;       791 AA.
AC   A0A2I0G174;
DT   28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT   28-FEB-2018, sequence version 1.
DT   24-JAN-2024, entry version 15.
DE   SubName: Full=Membrane-bound PQQ-dependent dehydrogenase, glucose/quinate/shikimate family {ECO:0000313|EMBL:PKH26713.1};
GN   ORFNames=CIG19_02660 {ECO:0000313|EMBL:PKH26713.1};
OS   Enterobacterales bacterium CwR94.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales.
OX   NCBI_TaxID=2025587 {ECO:0000313|EMBL:PKH26713.1, ECO:0000313|Proteomes:UP000237543};
RN   [1] {ECO:0000313|EMBL:PKH26713.1, ECO:0000313|Proteomes:UP000237543}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CwR94 {ECO:0000313|EMBL:PKH26713.1,
RC   ECO:0000313|Proteomes:UP000237543};
RA   de Groot N.N.;
RL   Submitted (AUG-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=pyrroloquinoline quinone; Xref=ChEBI:CHEBI:58442;
CC         Evidence={ECO:0000256|ARBA:ARBA00001931};
CC   -!- SIMILARITY: Belongs to the bacterial PQQ dehydrogenase family.
CC       {ECO:0000256|ARBA:ARBA00008156}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PKH26713.1}.
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DR   EMBL; NVXY01000001; PKH26713.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2I0G174; -.
DR   OrthoDB; 9794322at2; -.
DR   Proteomes; UP000237543; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0016614; F:oxidoreductase activity, acting on CH-OH group of donors; IEA:InterPro.
DR   GO; GO:0048038; F:quinone binding; IEA:InterPro.
DR   CDD; cd10280; PQQ_mGDH; 1.
DR   Gene3D; 2.140.10.10; Quinoprotein alcohol dehydrogenase-like superfamily; 1.
DR   InterPro; IPR018391; PQQ_beta_propeller_repeat.
DR   InterPro; IPR017511; PQQ_mDH.
DR   InterPro; IPR002372; PQQ_repeat.
DR   InterPro; IPR011047; Quinoprotein_ADH-like_supfam.
DR   NCBIfam; TIGR03074; PQQ_membr_DH; 1.
DR   PANTHER; PTHR32303; QUINOPROTEIN ALCOHOL DEHYDROGENASE (CYTOCHROME C); 1.
DR   PANTHER; PTHR32303:SF4; QUINOPROTEIN GLUCOSE DEHYDROGENASE; 1.
DR   Pfam; PF01011; PQQ; 2.
DR   Pfam; PF13360; PQQ_2; 1.
DR   SMART; SM00564; PQQ; 5.
DR   SUPFAM; SSF50998; Quinoprotein alcohol dehydrogenase-like; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Reference proteome {ECO:0000313|Proteomes:UP000237543};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        7..26
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        32..48
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        55..74
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        86..104
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        116..134
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   791 AA;  86924 MW;  B8FB10E51BD55AF6 CRC64;
     MVTKLTSIII AIIGIAMLYM GGQLIAVGGS PFYAILAVGL ILTAILLFMN KKIALSVYAI
     LMWITLAWII WEAGFDKWQW IPRGDVIGLI GLWLAMPFIV RPLTRRRGVA QGFHPFLGTT
     VVVMIAIVIG LFFYDPYPQK GTLTNERQPA DTEVAKQDWA AYGGNDNGQR FSALNQITKD
     NVKNLELAWQ YHTGDVRDPK TDASEYTFEA TPLKVNDTLY FCTPHNEVHA LEPETGKLKW
     KYTPAKDRTN QRQHQTCRGV SYYAAPQAVA ANETVAPALC RKRIYQGTTD AKLIALDADT
     GKLCADFGNN GIIDLSHNMG PVRPTALMQT AAPLVAGDLV IVGGSVMDNG FHQGNPGGVI
     RAYNAISGEL VWNFDPGKPD DTQPIAADGI YTQDTPTAWT TLSADIQNGL VYVPFGNASP
     DEVGIDRDAN SNTEKFRDTL VALDLRTGEF KWRFQSSHHD LWDRDNPSQV SLLDIDYQGK
     KQPVVILPTK VGNLFVLNRL TGQPVYPVNL QQVSTEGGVT GEKFAPNQPV SALNFIPAPL
     EEKAMWGVSP FDQMACRIEF KQRRYDGNPW TPATEQGSIV FPGNIGVFNW GSVAVDPERQ
     ILVATPIRIA HRYNMVKRTQ ETNEQRLISK DGQPIFNENF DGSYAFRIAQ FASGLGIPCI
     APPWGRMAAV DLKSGKTEWL RRTGTTKNLN TTFLPFPFPV GFPMGMIAHG GPLVTGGDLV
     FHAATADNFF RAYDINTGEL LWETELPAGG QATPSSFMGK DNQQYVVIAA GGHGSIGTKQ
     GDSVMAYRVK Q
//