ID   A0A2I0HRK6_PUNGR        Unreviewed;       932 AA.
AC   A0A2I0HRK6;
DT   28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT   28-FEB-2018, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   RecName: Full=TIR domain-containing protein {ECO:0000259|PROSITE:PS50104};
GN   ORFNames=CRG98_045716 {ECO:0000313|EMBL:PKI33886.1};
OS   Punica granatum (Pomegranate).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Myrtales; Lythraceae; Punica.
OX   NCBI_TaxID=22663 {ECO:0000313|EMBL:PKI33886.1, ECO:0000313|Proteomes:UP000233551};
RN   [1] {ECO:0000313|EMBL:PKI33886.1, ECO:0000313|Proteomes:UP000233551}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. AG2017 {ECO:0000313|Proteomes:UP000233551};
RC   TISSUE=Leaf {ECO:0000313|EMBL:PKI33886.1};
RA   Akparov Z., Amiraslanov A., Hajiyeva S., Abbasov M., Kaur K., Hamwieh A.,
RA   Solovyev V., Salamov A., Braich B., Kosarev P., Mahmoud A., Hajiyev E.,
RA   Babayeva S., Izzatullayeva V., Mammadov A., Mammadov A., Sharifova S.,
RA   Ojaghi J., Eynullazada K., Bayramov B., Abdulazimova A., Shahmuradov I.;
RT   "De-novo sequencing of pomegranate (Punica granatum L.) genome.";
RL   Submitted (NOV-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PKI33886.1}.
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DR   EMBL; PGOL01006246; PKI33886.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2I0HRK6; -.
DR   STRING; 22663.A0A2I0HRK6; -.
DR   Proteomes; UP000233551; Unassembled WGS sequence.
DR   GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR   GO; GO:0006952; P:defense response; IEA:InterPro.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   Gene3D; 1.10.8.430; Helical domain of apoptotic protease-activating factors; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 2.
DR   Gene3D; 3.40.50.10140; Toll/interleukin-1 receptor homology (TIR) domain; 1.
DR   InterPro; IPR042197; Apaf_helical.
DR   InterPro; IPR044974; Disease_R_plants.
DR   InterPro; IPR032675; LRR_dom_sf.
DR   InterPro; IPR002182; NB-ARC.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR000157; TIR_dom.
DR   InterPro; IPR035897; Toll_tir_struct_dom_sf.
DR   PANTHER; PTHR11017:SF580; DISEASE RESISTANCE-LIKE PROTEIN DSC1; 1.
DR   PANTHER; PTHR11017; LEUCINE-RICH REPEAT-CONTAINING PROTEIN; 1.
DR   Pfam; PF00931; NB-ARC; 1.
DR   Pfam; PF01582; TIR; 1.
DR   PRINTS; PR00364; DISEASERSIST.
DR   SMART; SM00255; TIR; 1.
DR   SUPFAM; SSF52058; L domain-like; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   SUPFAM; SSF52200; Toll/Interleukin receptor TIR domain; 1.
DR   PROSITE; PS50104; TIR; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000233551}.
FT   DOMAIN          14..179
FT                   /note="TIR"
FT                   /evidence="ECO:0000259|PROSITE:PS50104"
SQ   SEQUENCE   932 AA;  106170 MW;  93E3D9D5B1A24201 CRC64;
     MAPNRNNNTS SPPPSYQVFL SFRGPDTRQG FTDVLYHTLV DAGIRVFRDN EEIRKGEYIG
     EEILRAIEDS RIFVPIFSRT YASSKWCLIE LAKMVESKEY SHNKKILPIF YDVGVNDVKL
     KTELYTGALL IHKEKFSTDI VHQWEEALRD AGKIKGWALK DKGFAEFAKE FVREVSAELK
     VKQKYVTGSL VERIDLQDAL TMLLDVDSSL DVRLVWIHGM GGIGKTTLAK DVFNRLCNHF
     KHCSFLLDVQ ETTKRKGIEH LQRQLLQDLG VKAADITDEN DGIQIISEKL QNRKVLVVLD
     DVHDHQEHIG KLAREASWFG VGSRIIITSR SRRVPAFEGG TVKIFEAKPM EFEESLLLFS
     RHAFGKESPP HDSLDLSKEA VRITGGLPLA LEVIGSKLRT SDRDHWNHMI GTLQKIPARK
     VQDRLKICYD ALDWEVKEIF LDIACFFINE EKTKAIYMWQ ACDFEPELAV QELVDASLVK
     LTDENKFRMH DQLRDLGRKL VRDERLKHHG KPCSRIWMHE DALKVLHDEE GREKVEMLSL
     SSKGPSEDCV LTKHELKNFN NLRFLSLIRS KFSGDLEHIL PKLIWLSWHS CPGVFEGTNL
     YLKNLVVLDL SESSVSETWT GWRHIGMCKE LKVLDLKRCD LLIKTPNLSM CTKLERLILK
     GCINLVEIDH SVGKLKCLKY LNASGCSNLR EIPREVCCLD GLVDIVMTME GSFKDSNKLP
     DSIGRLSRLQ RLRVSLGRSR PPSSLGDLKS LTMLVLSWSR MTGLPESIGG LVKLEFLSLF
     FCGGVKELPA SIRNLKSLAE LNISKSGITQ LPDAVGNLQK LKVIDMRGCV IRRLPDFLGN
     LEKLERLDIF GCNYLQDIPS AIKGITSLLE VSPSAWDKSC ERYWKLRVQL RKWGLYHTWG
     SVLNGQNFYL RSVVAVSADF VIHLSWVKNF GV
//