ID A0A2I0JJE2_PUNGR Unreviewed; 407 AA.
AC A0A2I0JJE2;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Two-pore potassium channel 3-like isoform X1 {ECO:0000313|RefSeq:XP_031391832.1};
GN Name=LOC116203973 {ECO:0000313|RefSeq:XP_031391832.1};
GN ORFNames=CRG98_023912 {ECO:0000313|EMBL:PKI55696.1};
OS Punica granatum (Pomegranate).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Myrtales; Lythraceae; Punica.
OX NCBI_TaxID=22663 {ECO:0000313|EMBL:PKI55696.1, ECO:0000313|Proteomes:UP000233551};
RN [1] {ECO:0000313|EMBL:PKI55696.1, ECO:0000313|Proteomes:UP000233551}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AG2017 {ECO:0000313|EMBL:PKI55696.1}, and cv. AG2017
RC {ECO:0000313|Proteomes:UP000233551};
RC TISSUE=Leaf {ECO:0000313|EMBL:PKI55696.1};
RA Akparov Z., Amiraslanov A., Hajiyeva S., Abbasov M., Kaur K., Hamwieh A.,
RA Solovyev V., Salamov A., Braich B., Kosarev P., Mahmoud A., Hajiyev E.,
RA Babayeva S., Izzatullayeva V., Mammadov A., Mammadov A., Sharifova S.,
RA Ojaghi J., Eynullazada K., Bayramov B., Abdulazimova A., Shahmuradov I.;
RT "De-novo sequencing of pomegranate (Punica granatum L.) genome.";
RL Submitted (NOV-2017) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|RefSeq:XP_031391832.1}
RP IDENTIFICATION.
RC TISSUE=Leaf {ECO:0000313|RefSeq:XP_031391832.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the two pore domain potassium channel (TC
CC 1.A.1.7) family. {ECO:0000256|ARBA:ARBA00010159}.
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DR EMBL; PGOL01001681; PKI55696.1; -; Genomic_DNA.
DR RefSeq; XP_031391832.1; XM_031535972.1.
DR STRING; 22663.A0A2I0JJE2; -.
DR OrthoDB; 38977at2759; -.
DR Proteomes; UP000233551; Unassembled WGS sequence.
DR Proteomes; UP000515151; Chromosome 4.
DR GO; GO:0005774; C:vacuolar membrane; IEA:UniProt.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0005267; F:potassium channel activity; IEA:InterPro.
DR Gene3D; 1.10.287.70; -; 2.
DR Gene3D; 1.10.238.10; EF-hand; 1.
DR InterPro; IPR003280; 2pore_dom_K_chnl.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR InterPro; IPR002048; EF_hand_dom.
DR InterPro; IPR013099; K_chnl_dom.
DR PANTHER; PTHR11003:SF303; OS01G0696100 PROTEIN; 1.
DR PANTHER; PTHR11003; POTASSIUM CHANNEL, SUBFAMILY K; 1.
DR Pfam; PF13202; EF-hand_5; 1.
DR Pfam; PF07885; Ion_trans_2; 2.
DR PRINTS; PR01333; 2POREKCHANEL.
DR SUPFAM; SSF47473; EF-hand; 1.
DR SUPFAM; SSF81324; Voltage-gated potassium channels; 2.
DR PROSITE; PS00018; EF_HAND_1; 1.
PE 3: Inferred from homology;
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Ion channel {ECO:0000313|RefSeq:XP_031391832.1};
KW Ion transport {ECO:0000313|RefSeq:XP_031391832.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000233551};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 128..146
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 158..176
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 182..202
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 248..269
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 302..323
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 132..209
FT /note="Potassium channel"
FT /evidence="ECO:0000259|Pfam:PF07885"
FT DOMAIN 257..323
FT /note="Potassium channel"
FT /evidence="ECO:0000259|Pfam:PF07885"
FT DOMAIN 348..364
FT /note="EF-hand"
FT /evidence="ECO:0000259|Pfam:PF13202"
FT REGION 1..42
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 407 AA; 45227 MW; F99E793A95EA26E0 CRC64;
MDIDEPLLSR SPGGFSSPST SRSSRPHIKR EFPSGFLDLP LPTPRGRQST AHLLSTSDVI
IPIIATAAAS HPSSGSYVNL IANLNERRRL THRSNSSPAV FTDAKESISR PMDPRPARKS
NPFIVRQAFI GLILYVIIGV VVFLVSGNFK GHETYKPVDA LYFTVVTLCT IGYGDIVPDT
TFTKLFTCAF IIIGFGFVDI LLNGLVTYIC DRQEAVMLGT VDESRFNTMV RAYMVDAAKG
RMRIRLKVAI ALMIPVCCIA VGTIAIRYLE SLPWVDSFYM AVTSVTTVGY GDFSFTTVQG
RVFAIIWLLV STLTVARAFL YLTELRIDKR NRRIAKWVLQ KKMTLGDLIA ADLDHDGSIS
KSEFVIYKLK EMGKIAQKDI MQICDQFDLL DHTKNGKITL ADLMDSD
//
