ID A0A2I0KHY4_PUNGR Unreviewed; 710 AA.
AC A0A2I0KHY4;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE RecName: Full=CSC1-like protein ERD4 {ECO:0008006|Google:ProtNLM};
GN ORFNames=CRG98_011694 {ECO:0000313|EMBL:PKI68098.1};
OS Punica granatum (Pomegranate).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Myrtales; Lythraceae; Punica.
OX NCBI_TaxID=22663 {ECO:0000313|EMBL:PKI68098.1, ECO:0000313|Proteomes:UP000233551};
RN [1] {ECO:0000313|EMBL:PKI68098.1, ECO:0000313|Proteomes:UP000233551}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. AG2017 {ECO:0000313|Proteomes:UP000233551};
RC TISSUE=Leaf {ECO:0000313|EMBL:PKI68098.1};
RA Akparov Z., Amiraslanov A., Hajiyeva S., Abbasov M., Kaur K., Hamwieh A.,
RA Solovyev V., Salamov A., Braich B., Kosarev P., Mahmoud A., Hajiyev E.,
RA Babayeva S., Izzatullayeva V., Mammadov A., Mammadov A., Sharifova S.,
RA Ojaghi J., Eynullazada K., Bayramov B., Abdulazimova A., Shahmuradov I.;
RT "De-novo sequencing of pomegranate (Punica granatum L.) genome.";
RL Submitted (NOV-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the CSC1 (TC 1.A.17) family.
CC {ECO:0000256|ARBA:ARBA00007779}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PKI68098.1}.
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DR EMBL; PGOL01000571; PKI68098.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2I0KHY4; -.
DR STRING; 22663.A0A2I0KHY4; -.
DR Proteomes; UP000233551; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005227; F:calcium-activated cation channel activity; IEA:InterPro.
DR InterPro; IPR045122; Csc1-like.
DR InterPro; IPR003864; CSC1/OSCA1-like_7TM.
DR InterPro; IPR027815; CSC1/OSCA1-like_cyt.
DR InterPro; IPR032880; Csc1/OSCA1-like_N.
DR PANTHER; PTHR13018:SF100; CSC1-LIKE PROTEIN ERD4; 1.
DR PANTHER; PTHR13018; PROBABLE MEMBRANE PROTEIN DUF221-RELATED; 1.
DR Pfam; PF14703; PHM7_cyt; 1.
DR Pfam; PF02714; RSN1_7TM; 1.
DR Pfam; PF13967; RSN1_TM; 1.
PE 3: Inferred from homology;
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Ion channel {ECO:0000256|ARBA:ARBA00023303};
KW Ion transport {ECO:0000256|ARBA:ARBA00023303};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000233551};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 6..27
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 82..107
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 146..165
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 355..381
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 406..426
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 446..468
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 488..507
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 552..581
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 630..647
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 5..166
FT /note="CSC1/OSCA1-like N-terminal transmembrane"
FT /evidence="ECO:0000259|Pfam:PF13967"
FT DOMAIN 188..331
FT /note="CSC1/OSCA1-like cytosolic"
FT /evidence="ECO:0000259|Pfam:PF14703"
FT DOMAIN 353..623
FT /note="CSC1/OSCA1-like 7TM region"
FT /evidence="ECO:0000259|Pfam:PF02714"
SQ SEQUENCE 710 AA; 80337 MW; 8968DD4BDB34E92B CRC64;
MDLSSFVTSL VTSFLLFVVL MLLFAWLSRK PGNMFVYYPN RILKGLDPID TGYAARNPFA
WAREALSSTE QDVIAMSGID TAVYFVFLST VLGILVLSGL LLLPVLLPVA ATDNSAKPSN
STTSNGTFND VDKLSMGNIG ENNNRLWAFL IATYWVSFVT YYLLWKAYKH VSELRANALE
SPEVKPEQFA VLVRDIPDLP EGQTRKEQID SYFKSIYPET FYRSMVVTNN KQVNKIYEEL
EGYKKKLIRA EAIYADSKTT GKPEGTRPTN KTGFLGLCGE KVDSIEYYSE KIKELLPKLE
AEQKATLREK QQGAALVFFT SRVTAASAAQ SLHAQILIWT NLNIKFFSRQ VRQNVVYVIV
VLTIFFYMIP IGFISAFTTL ANLRKLLPFL KVIVDQAAIK TVLEAYLPQI ALIVFLALLP
KFLLFLSKTE GIPSQSHIER AASGKFFYFS VLNVFIGVTV GGTLFSTFKQ IEKDPNSVVT
LLAQSLPGNA TFFLTFVALK FFVGYGLELS RIVPLIIFHL KKKYLCKTED EIKEAWFPGD
LHYATRVPGD MLIVTIVLCY SVIAPLIIPF GVVYFGLGWL IHRNQAIKVY VPSYESYGRM
WPHMHARILA SLVLYQLTMF GYFGTKKFPY TVILIPGIIF SLIFAYVCKQ KFYRFFHDTA
LEVATQEAKE TPNMEQIFRA YIPPSLSNEK IDDDQYEDAL SQVPRSTSFV
//
