ID   A0A2I0L3E5_PUNGR        Unreviewed;       714 AA.
AC   A0A2I0L3E5;
DT   28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT   28-FEB-2018, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   RecName: Full=Protein-tyrosine-phosphatase MKP1 {ECO:0008006|Google:ProtNLM};
GN   ORFNames=CRG98_004993 {ECO:0000313|EMBL:PKI74666.1};
OS   Punica granatum (Pomegranate).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Myrtales; Lythraceae; Punica.
OX   NCBI_TaxID=22663 {ECO:0000313|EMBL:PKI74666.1, ECO:0000313|Proteomes:UP000233551};
RN   [1] {ECO:0000313|EMBL:PKI74666.1, ECO:0000313|Proteomes:UP000233551}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. AG2017 {ECO:0000313|Proteomes:UP000233551};
RC   TISSUE=Leaf {ECO:0000313|EMBL:PKI74666.1};
RA   Akparov Z., Amiraslanov A., Hajiyeva S., Abbasov M., Kaur K., Hamwieh A.,
RA   Solovyev V., Salamov A., Braich B., Kosarev P., Mahmoud A., Hajiyev E.,
RA   Babayeva S., Izzatullayeva V., Mammadov A., Mammadov A., Sharifova S.,
RA   Ojaghi J., Eynullazada K., Bayramov B., Abdulazimova A., Shahmuradov I.;
RT   "De-novo sequencing of pomegranate (Punica granatum L.) genome.";
RL   Submitted (NOV-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PKI74666.1}.
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DR   EMBL; PGOL01000196; PKI74666.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2I0L3E5; -.
DR   STRING; 22663.A0A2I0L3E5; -.
DR   Proteomes; UP000233551; Unassembled WGS sequence.
DR   GO; GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro.
DR   GO; GO:0016311; P:dephosphorylation; IEA:InterPro.
DR   CDD; cd14498; DSP; 1.
DR   Gene3D; 3.90.190.10; Protein tyrosine phosphatase superfamily; 1.
DR   Gene3D; 3.40.20.10; Severin; 1.
DR   InterPro; IPR029006; ADF-H/Gelsolin-like_dom_sf.
DR   InterPro; IPR000340; Dual-sp_phosphatase_cat-dom.
DR   InterPro; IPR029021; Prot-tyrosine_phosphatase-like.
DR   InterPro; IPR016130; Tyr_Pase_AS.
DR   InterPro; IPR000387; Tyr_Pase_dom.
DR   InterPro; IPR020422; TYR_PHOSPHATASE_DUAL_dom.
DR   PANTHER; PTHR46381; MKPA PROTEIN; 1.
DR   PANTHER; PTHR46381:SF4; MKPA PROTEIN; 1.
DR   Pfam; PF00782; DSPc; 1.
DR   SMART; SM00195; DSPc; 1.
DR   SUPFAM; SSF52799; (Phosphotyrosine protein) phosphatases II; 1.
DR   SUPFAM; SSF55753; Actin depolymerizing proteins; 1.
DR   PROSITE; PS00383; TYR_PHOSPHATASE_1; 1.
DR   PROSITE; PS50056; TYR_PHOSPHATASE_2; 1.
DR   PROSITE; PS50054; TYR_PHOSPHATASE_DUAL; 1.
PE   4: Predicted;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Protein phosphatase {ECO:0000256|ARBA:ARBA00022912};
KW   Reference proteome {ECO:0000313|Proteomes:UP000233551}.
FT   DOMAIN          144..286
FT                   /note="Tyrosine-protein phosphatase"
FT                   /evidence="ECO:0000259|PROSITE:PS50054"
FT   DOMAIN          213..264
FT                   /note="Tyrosine specific protein phosphatases"
FT                   /evidence="ECO:0000259|PROSITE:PS50056"
FT   REGION          1..73
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          86..114
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        13..48
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        57..72
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   714 AA;  79490 MW;  456BAD992A6F483C CRC64;
     MVGKEDPNAR KTFWRSASWS ASRTAQQNPN GVEEVNGSDP NGSNPESFGA NRRFPVPLTP
     RSQQNWKNRS CLPPLQPLSI ARRSLDDWPK AGSDDVGEWP QPPTPSGNSK GGERLKLDMS
     AIQRAPDRNG GLVKREKIAF FDKECSKVAE HIYLGGDAVA RDRNILKQNG ITHVLNCVGF
     VCPEYFKADF VYRTLWLQDS PTEDITSILY DVFDYFEDVR EQHGRVFVHC CQGVSRSTSL
     VIAYLMWREG QSFDDAFQFV KAARGIADPN MGFACQLLQC QKRVHAFPLS PSSLLRMYRL
     APHSPYDPLH LVPKMLTDPS PSALDSRGAF IVQVPSSIYV WIGRDCEAIM ERDARGAVCQ
     IVRYERVQGP VLMIKEGGEP SYFWDAFSNL LPLMDKSGNG VAIKDQRAGK VGERKVDSYD
     VDFEIFQKAV KGGVVPPFAA SENEHETHLP ARESDWSMLR RKFAPSNMKE FVSVPKLILS
     RVYSDSMMPQ SASSHIRKLS LSLAERRGSM SRALKLPVMT DNVRFAEPPP NDLALKEDGI
     RLNGNGCSPS EFHLYSENMT NGVVDVMRER KLEESADAGV LPPREAACAR DPSGMAGSVC
     QCKEQMQLAV YRWPSLEKVA SIASSDLRSE AAFAILSVRK GLDKDLDRFV YLWIGRFFAV
     DKGKAHIGRG TGIDDPEKID WEQVGYDFLS RIGLPKDTNI KQAIGKGAVG GLPS
//