ID   A0A2I0L682_PUNGR        Unreviewed;       519 AA.
AC   A0A2I0L682;
DT   28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT   28-FEB-2018, sequence version 1.
DT   27-MAR-2024, entry version 27.
DE   RecName: Full=ceramide glucosyltransferase {ECO:0000256|ARBA:ARBA00012699};
DE            EC=2.4.1.80 {ECO:0000256|ARBA:ARBA00012699};
GN   Name=LOC116199614 {ECO:0000313|RefSeq:XP_031385908.1};
GN   ORFNames=CRG98_003336 {ECO:0000313|EMBL:PKI76225.1};
OS   Punica granatum (Pomegranate).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Myrtales; Lythraceae; Punica.
OX   NCBI_TaxID=22663 {ECO:0000313|EMBL:PKI76225.1, ECO:0000313|Proteomes:UP000233551};
RN   [1] {ECO:0000313|EMBL:PKI76225.1, ECO:0000313|Proteomes:UP000233551}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AG2017 {ECO:0000313|EMBL:PKI76225.1}, and cv. AG2017
RC   {ECO:0000313|Proteomes:UP000233551};
RC   TISSUE=Leaf {ECO:0000313|EMBL:PKI76225.1};
RA   Akparov Z., Amiraslanov A., Hajiyeva S., Abbasov M., Kaur K., Hamwieh A.,
RA   Solovyev V., Salamov A., Braich B., Kosarev P., Mahmoud A., Hajiyev E.,
RA   Babayeva S., Izzatullayeva V., Mammadov A., Mammadov A., Sharifova S.,
RA   Ojaghi J., Eynullazada K., Bayramov B., Abdulazimova A., Shahmuradov I.;
RT   "De-novo sequencing of pomegranate (Punica granatum L.) genome.";
RL   Submitted (NOV-2017) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|RefSeq:XP_031385908.1}
RP   IDENTIFICATION.
RC   TISSUE=Leaf {ECO:0000313|RefSeq:XP_031385908.1};
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- PATHWAY: Lipid metabolism; sphingolipid metabolism.
CC       {ECO:0000256|ARBA:ARBA00004760}.
CC   -!- PATHWAY: Sphingolipid metabolism. {ECO:0000256|ARBA:ARBA00004991}.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the glycosyltransferase 2 family.
CC       {ECO:0000256|ARBA:ARBA00006739}.
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DR   EMBL; PGOL01000126; PKI76225.1; -; Genomic_DNA.
DR   RefSeq; XP_031385908.1; XM_031530048.1.
DR   STRING; 22663.A0A2I0L682; -.
DR   OrthoDB; 444471at2759; -.
DR   UniPathway; UPA00222; -.
DR   Proteomes; UP000233551; Unassembled WGS sequence.
DR   Proteomes; UP000515151; Chromosome 3.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0008120; F:ceramide glucosyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0102769; F:dihydroceramide glucosyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006665; P:sphingolipid metabolic process; IEA:UniProtKB-UniPathway.
DR   InterPro; IPR025993; Ceramide_glucosylTrfase.
DR   InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR   PANTHER; PTHR12726; CERAMIDE GLUCOSYLTRANSFERASE; 1.
DR   PANTHER; PTHR12726:SF0; CERAMIDE GLUCOSYLTRANSFERASE; 1.
DR   Pfam; PF13506; Glyco_transf_21; 1.
DR   SUPFAM; SSF53448; Nucleotide-diphospho-sugar transferases; 1.
PE   3: Inferred from homology;
KW   Glycosyltransferase {ECO:0000256|ARBA:ARBA00022676};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000233551};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        22..47
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        342..366
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        378..401
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   519 AA;  58204 MW;  330DF94549904D25 CRC64;
     MSALDSIDSF LFSLSRAFCS PLAVFVQIQG CLICLILALG WALAAYVRNR EIRRMKDSTR
     RGNSFAFLCH DINELEHSRQ AQLPRVSVVM PLKGFGEHNL HNWRSQITSL YGGPLEFIFI
     VESTEDPAYH AVSLLISDFQ GEVDAKVIVA GLSTTCSQKI HNQLVGVENM HKDSKYVLFL
     DDDVRLHPGS IGALTAEMEK NPEIFIQTGY PLDLPSGSLG SYCIYEYHMP CSMGFATGGR
     TFFLWGGCMM MHADHFRYDH CGVVSGLRDG GYSDDMTLAA IAGAHKKLIT SPPVAVFPHP
     LSSDLSFSRY WNYLRKQTFV LESYTTKVNW IMNRALFTSH CYLSWGFVAP YLMAVVHVTA
     ALRVYVKGYR LEETSLTSTG LLMVTCLAAC TLTELFSMWN LTRIEVELCN LLSPEAPKLS
     LASYNWSLVF IAMLVDNFLY TISAVRSHFS QSINWSGIRY HLKDGKISKI DRSKNMGPKF
     TDLGGKNLYG KKGLPPKGSF VISLARSLAQ WRQPKKYDV
//