ID A0A2I0LIF0_COLLI Unreviewed; 956 AA.
AC A0A2I0LIF0;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 28-JUN-2023, entry version 10.
DE RecName: Full=MAM domain-containing protein {ECO:0000259|PROSITE:PS50060};
DE Flags: Fragment;
GN ORFNames=A306_00000126 {ECO:0000313|EMBL:PKK17222.1};
OS Columba livia (Rock dove).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Columbiformes; Columbidae; Columba.
OX NCBI_TaxID=8932 {ECO:0000313|EMBL:PKK17222.1, ECO:0000313|Proteomes:UP000053872};
RN [1] {ECO:0000313|EMBL:PKK17222.1, ECO:0000313|Proteomes:UP000053872}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC TISSUE=Blood {ECO:0000313|EMBL:PKK17222.1};
RX PubMed=23371554; DOI=10.1126/science.1230422;
RA Shapiro M.D., Kronenberg Z., Li C., Domyan E.T., Pan H., Campbell M.,
RA Tan H., Huff C.D., Hu H., Vickrey A.I., Nielsen S.C., Stringham S.A.,
RA Hu H., Willerslev E., Gilbert M.T., Yandell M., Zhang G., Wang J.;
RT "Genomic diversity and evolution of the head crest in the rock pigeon.";
RL Science 339:1063-1067(2013).
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00124}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PKK17222.1}.
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DR EMBL; AKCR02000383; PKK17222.1; -; Genomic_DNA.
DR InParanoid; A0A2I0LIF0; -.
DR Proteomes; UP000053872; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd00112; LDLa; 2.
DR CDD; cd06263; MAM; 3.
DR Gene3D; 2.60.120.200; -; 4.
DR Gene3D; 4.10.400.10; Low-density Lipoprotein Receptor; 1.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR036055; LDL_receptor-like_sf.
DR InterPro; IPR023415; LDLR_class-A_CS.
DR InterPro; IPR002172; LDrepeatLR_classA_rpt.
DR InterPro; IPR000998; MAM_dom.
DR PANTHER; PTHR23282:SF129; APICAL ENDOSOMAL GLYCOPROTEIN; 1.
DR PANTHER; PTHR23282; APICAL ENDOSOMAL GLYCOPROTEIN PRECURSOR; 1.
DR Pfam; PF00057; Ldl_recept_a; 2.
DR Pfam; PF00629; MAM; 4.
DR PRINTS; PR00261; LDLRECEPTOR.
DR PRINTS; PR00020; MAMDOMAIN.
DR SMART; SM00192; LDLa; 2.
DR SMART; SM00137; MAM; 3.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 4.
DR SUPFAM; SSF57424; LDL receptor-like module; 2.
DR PROSITE; PS01209; LDLRA_1; 2.
DR PROSITE; PS50068; LDLRA_2; 2.
DR PROSITE; PS50060; MAM_2; 5.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00124}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000053872};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 908..930
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 53..209
FT /note="MAM"
FT /evidence="ECO:0000259|PROSITE:PS50060"
FT DOMAIN 245..413
FT /note="MAM"
FT /evidence="ECO:0000259|PROSITE:PS50060"
FT DOMAIN 423..577
FT /note="MAM"
FT /evidence="ECO:0000259|PROSITE:PS50060"
FT DOMAIN 692..721
FT /note="MAM"
FT /evidence="ECO:0000259|PROSITE:PS50060"
FT DOMAIN 723..890
FT /note="MAM"
FT /evidence="ECO:0000259|PROSITE:PS50060"
FT DISULFID 20..38
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 228..240
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 235..253
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 247..262
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT NON_TER 956
FT /evidence="ECO:0000313|EMBL:PKK17222.1"
SQ SEQUENCE 956 AA; 102807 MW; B10FB57B8E5BE859 CRC64;
MVCPTAAEPG QQVCVEESRC RRGSCLAQHR FCDGTDDCGD GSDEDAERCN SFRHCSFEEG
LCSWEVEVAQ PMWERNTSLN LGTSYGIPTR DHSSNSRAGF FLHVGSTSAT GAGSTARLSS
STLKANKSCS LVLYCHLHGS ATSSLSISYV TNSTKHLVRE RTGDLGNCWV RERVDFNVTE
SFKVLIEGVA SGTGTVAIDD LFLSPGCVWH QEEEASTTLP SRAGAGPCAA GEVPCDSGSC
INAELACDFA ETCADGSDEK RCGATTSEAG AEGWHDVSVG QLRWAVQRAT EPTNTVLTGD
FLIIQAGEGQ MVAPAKARTP LLGPSGPACA MEMSYHIHSG PQGFLAVSIT DHSTGTKHLA
WHTQGHDGMA RGHVHVPLGE RTRPFQVELL GLVDLQDSAT AGIDNVTFVQ CHPDVVPPGA
AELSCNFEKG MCGWYQDPSS DFQWVRSTGQ GQGSDHTTGS GYFLAVDPAA LWSHGQRAQL
VTYWQGPMAT PRCLSFWYRL AGPQIGTLNL KLRLEGEEET VLWTQRGTRG SIWHRGQATL
PATGQRQYRV AFEALRDGFL GDMALDDVAL TAGPCGADLS CSFEADACGL AASGQHSWLR
QXXXXXXXXX XXXXXXXXXX XXXXXXXPAC PEGPLHGGEH GQGLPAGQAH GCTHIPAVPA
LCARPVPGLL VPAEHRDPSH QPQRATLNIV RQVIFEAVGA GSDHGYMALD DLHVSDGVCP
EPVSCDFEQD TCGWSSPADP RLHSFAWGWK NGIPLAKYPG PEQDHTLGTR DGRYVHFDTG
VLGTGGTIAR LESQHLPAAA DACLRFWYHM DIPEHLACGE LRVMLQSVAG QRTVWSMAGH
QSRGWHSGVV PVQSPSEFQI IFEVTTRRWP MEGTVALDDI IYSTGGSCHS RLDMLVEEKP
SGSFVAEVVL SLLLAIVVLA LVATGSWYWL KKRVLASGQP AESNAPQGFD NITFRD
//
