ID A0A2I0LKF3_COLLI Unreviewed; 616 AA.
AC A0A2I0LKF3;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Zinc finger protein 687 {ECO:0000313|EMBL:PKK17918.1};
GN Name=ZNF687 {ECO:0000313|EMBL:PKK17918.1};
GN ORFNames=A306_00013579 {ECO:0000313|EMBL:PKK17918.1};
OS Columba livia (Rock dove).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Columbiformes; Columbidae; Columba.
OX NCBI_TaxID=8932 {ECO:0000313|EMBL:PKK17918.1, ECO:0000313|Proteomes:UP000053872};
RN [1] {ECO:0000313|EMBL:PKK17918.1, ECO:0000313|Proteomes:UP000053872}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC TISSUE=Blood {ECO:0000313|EMBL:PKK17918.1};
RX PubMed=23371554; DOI=10.1126/science.1230422;
RA Shapiro M.D., Kronenberg Z., Li C., Domyan E.T., Pan H., Campbell M.,
RA Tan H., Huff C.D., Hu H., Vickrey A.I., Nielsen S.C., Stringham S.A.,
RA Hu H., Willerslev E., Gilbert M.T., Yandell M., Zhang G., Wang J.;
RT "Genomic diversity and evolution of the head crest in the rock pigeon.";
RL Science 339:1063-1067(2013).
CC -!- FUNCTION: May be involved in transcriptional regulation.
CC {ECO:0000256|ARBA:ARBA00003767}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the krueppel C2H2-type zinc-finger protein
CC family. {ECO:0000256|ARBA:ARBA00006991}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PKK17918.1}.
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DR EMBL; AKCR02000255; PKK17918.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2I0LKF3; -.
DR STRING; 8932.A0A2I0LKF3; -.
DR InParanoid; A0A2I0LKF3; -.
DR Proteomes; UP000053872; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 5.
DR InterPro; IPR045914; Zn532-like.
DR InterPro; IPR041697; Znf-C2H2_11.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR47222; ZINC FINGER PROTEIN 532-RELATED; 1.
DR PANTHER; PTHR47222:SF2; ZINC FINGER PROTEIN 687; 1.
DR Pfam; PF00096; zf-C2H2; 1.
DR Pfam; PF16622; zf-C2H2_11; 1.
DR SMART; SM00355; ZnF_C2H2; 12.
DR SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 4.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 7.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 5.
PE 3: Inferred from homology;
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00042};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000053872};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00042};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00042}.
FT DOMAIN 136..163
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 258..285
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 289..317
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 526..554
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 579..601
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT REGION 329..382
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 463..492
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 547..575
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 552..566
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 616 AA; 68696 MW; 2ACFCCA551023A66 CRC64;
MRIEVTCNHC TKRLVFFNKC SLLLHAREHK DKGLVMQCSH LVMRPIALDQ MIGQPDITPL
VSVTSFPAGK VTGVTQDALV AANGAQELPI LPLGSGAEQS SYSCFRCLEC KEQCKDKAGL
AAHFQQAVTT GTTSSTVCTT CPMIMSNRCS FNAHQRMHKN RPPHVCPECG GNFLLANFET
HLKEACLHFS RRVGYRCPSC AVVFGGVNSI KSHIQTSHCE VFHKCPICPM AFKSAPSAHA
HVYTQHPGFS NQQSKMIYKC AMCDTVFTHK PLLSSHFDQH LLNQRVSVFK CPDCPLLFAQ
KRTMLEHLKN THQPQKPKED LAKKVAVLLT PKQEPVETPV SKISEESSSS TEEDEPPSSP
ELRKTKRSRF QRKTGNKSKG SGWTCGVCHS WFPERDEYVS HMKKDHGKSV KKFPTEGKRT
FSSRLILEKH IQVRHGIKVT DQPKSQEVVI ACIGTGTAQV SARKRKLSSD EGDSCSEEPD
STTPPSKTHK GERKAPFRCR KCGYLASSSA DFQEHIPQHR TDESSHQCRE CGLCFTSQVS
LNRHRFITHK KKRSAGEPEE PGPRSPRDGA AQHAPDGKLS CKVCGRCFDT QLNLKTHFRT
HGMAFIRARQ NASPEN
//
