ID A0A2I0LKW3_COLLI Unreviewed; 633 AA.
AC A0A2I0LKW3;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 27-MAR-2024, entry version 14.
DE RecName: Full=FAST kinase domain-containing protein 4 {ECO:0000256|ARBA:ARBA00040471};
DE AltName: Full=Protein TBRG4 {ECO:0000256|ARBA:ARBA00043220};
DE AltName: Full=Transforming growth factor beta regulator 4 {ECO:0000256|ARBA:ARBA00042265};
GN Name=TBRG4 {ECO:0000313|EMBL:PKK18079.1};
GN ORFNames=A306_00014036 {ECO:0000313|EMBL:PKK18079.1};
OS Columba livia (Rock dove).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Columbiformes; Columbidae; Columba.
OX NCBI_TaxID=8932 {ECO:0000313|EMBL:PKK18079.1, ECO:0000313|Proteomes:UP000053872};
RN [1] {ECO:0000313|EMBL:PKK18079.1, ECO:0000313|Proteomes:UP000053872}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC TISSUE=Blood {ECO:0000313|EMBL:PKK18079.1};
RX PubMed=23371554; DOI=10.1126/science.1230422;
RA Shapiro M.D., Kronenberg Z., Li C., Domyan E.T., Pan H., Campbell M.,
RA Tan H., Huff C.D., Hu H., Vickrey A.I., Nielsen S.C., Stringham S.A.,
RA Hu H., Willerslev E., Gilbert M.T., Yandell M., Zhang G., Wang J.;
RT "Genomic diversity and evolution of the head crest in the rock pigeon.";
RL Science 339:1063-1067(2013).
CC -!- SUBCELLULAR LOCATION: Mitochondrion matrix
CC {ECO:0000256|ARBA:ARBA00004305}.
CC -!- SIMILARITY: Belongs to the FAST kinase family.
CC {ECO:0000256|ARBA:ARBA00038281}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PKK18079.1}.
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DR EMBL; AKCR02000233; PKK18079.1; -; Genomic_DNA.
DR RefSeq; XP_005512184.1; XM_005512127.2.
DR AlphaFoldDB; A0A2I0LKW3; -.
DR STRING; 8932.A0A2I0LKW3; -.
DR GeneID; 102095471; -.
DR KEGG; clv:102095471; -.
DR CTD; 9238; -.
DR InParanoid; A0A2I0LKW3; -.
DR OrthoDB; 5347066at2759; -.
DR Proteomes; UP000053872; Unassembled WGS sequence.
DR GO; GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.
DR GO; GO:0044528; P:regulation of mitochondrial mRNA stability; IEA:InterPro.
DR InterPro; IPR013579; FAST_2.
DR InterPro; IPR010622; FAST_Leu-rich.
DR InterPro; IPR013584; RAP.
DR PANTHER; PTHR21228:SF59; FAST KINASE DOMAIN-CONTAINING PROTEIN 4; 1.
DR PANTHER; PTHR21228; FAST LEU-RICH DOMAIN-CONTAINING; 1.
DR Pfam; PF06743; FAST_1; 1.
DR Pfam; PF08368; FAST_2; 1.
DR Pfam; PF08373; RAP; 1.
DR SMART; SM00952; RAP; 1.
DR PROSITE; PS51286; RAP; 1.
PE 3: Inferred from homology;
KW Mitochondrion {ECO:0000256|ARBA:ARBA00023128};
KW Reference proteome {ECO:0000313|Proteomes:UP000053872};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transit peptide {ECO:0000256|ARBA:ARBA00022946}.
FT SIGNAL 1..26
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 27..633
FT /note="FAST kinase domain-containing protein 4"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5014119484"
FT DOMAIN 563..621
FT /note="RAP"
FT /evidence="ECO:0000259|PROSITE:PS51286"
SQ SEQUENCE 633 AA; 71791 MW; 0B9C96E4693C0F25 CRC64;
MAARLVRRCC WRHFAAFVSA PSAATAALLV PPGKVPMPRA LPQAPLALFH TSSPPDWADG
FSVKEQVDDG RNPEYKVIGE LIETATSPQE LFQLSELHEL NSNHASLIIT QISRLASEKK
LETENIVRDE RFQQLIGIMD SQISQVWNNT LVNLLKSLYS LGVPSSRREM QSVEQEVLWR
LRRLTFRQLA SLAEFLAIRQ GKDNKLLNEV IKKLELRWTE LEGTRTVVTL MGKVGHVSPV
LMDRLEDKAL ELAEHFNPDE TRKILLALAY QNRRCVPLLR ALSYHLLQKH AELSLSILLD
LVFAYGKLNF HQPQVFQKIA SDLQPHVPAM APMEVTRCTR SFALLKWLSL PLFEAITQYA
LDNPKQLSVA HLCGIILSFA RLNFQPSGSE DFFNMVHEEL QGQLGSLEPQ MLTELVWSLC
VLQQARAPYL QRVLAPEFHA HIRGDQSLKA QNLQLKLIHI NAAAKLENPD YKGPFLPPEL
LSTVPLASER VTQLQSCLRE ALTGLLGSQD NGRFDVRTLY GWHIDAEMVV TSENKPLPVK
DFAAPHLLRA EGTKPLPPGA RRVAFLRWEF PNFSNRSKEL LGRYAMARRH VQAAGFLVVD
VPHYEFLELK LERQRTAYLR DKLHKVMAKD MAS
//
