ID A0A2I0LLC2_COLLI Unreviewed; 1429 AA.
AC A0A2I0LLC2;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Kinesin family member 24 {ECO:0000313|EMBL:PKK18218.1};
GN Name=KIF24 {ECO:0000313|EMBL:PKK18218.1};
GN ORFNames=A306_00014415 {ECO:0000313|EMBL:PKK18218.1};
OS Columba livia (Rock dove).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Columbiformes; Columbidae; Columba.
OX NCBI_TaxID=8932 {ECO:0000313|EMBL:PKK18218.1, ECO:0000313|Proteomes:UP000053872};
RN [1] {ECO:0000313|EMBL:PKK18218.1, ECO:0000313|Proteomes:UP000053872}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC TISSUE=Blood {ECO:0000313|EMBL:PKK18218.1};
RX PubMed=23371554; DOI=10.1126/science.1230422;
RA Shapiro M.D., Kronenberg Z., Li C., Domyan E.T., Pan H., Campbell M.,
RA Tan H., Huff C.D., Hu H., Vickrey A.I., Nielsen S.C., Stringham S.A.,
RA Hu H., Willerslev E., Gilbert M.T., Yandell M., Zhang G., Wang J.;
RT "Genomic diversity and evolution of the head crest in the rock pigeon.";
RL Science 339:1063-1067(2013).
CC -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC superfamily. Kinesin family. {ECO:0000256|PROSITE-ProRule:PRU00283}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PKK18218.1}.
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DR EMBL; AKCR02000220; PKK18218.1; -; Genomic_DNA.
DR RefSeq; XP_005507850.1; XM_005507793.1.
DR STRING; 8932.A0A2I0LLC2; -.
DR GeneID; 102090730; -.
DR KEGG; clv:102090730; -.
DR CTD; 347240; -.
DR InParanoid; A0A2I0LLC2; -.
DR OrthoDB; 239968at2759; -.
DR Proteomes; UP000053872; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR GO; GO:0003777; F:microtubule motor activity; IEA:InterPro.
DR GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
DR CDD; cd01367; KISc_KIF2_like; 1.
DR CDD; cd09541; SAM_KIF24-like; 1.
DR Gene3D; 3.40.850.10; Kinesin motor domain; 1.
DR Gene3D; 1.10.150.50; Transcription Factor, Ets-1; 1.
DR InterPro; IPR027640; Kinesin-like_fam.
DR InterPro; IPR019821; Kinesin_motor_CS.
DR InterPro; IPR001752; Kinesin_motor_dom.
DR InterPro; IPR036961; Kinesin_motor_dom_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR013761; SAM/pointed_sf.
DR PANTHER; PTHR47971:SF8; KINESIN-LIKE PROTEIN KIF24; 1.
DR PANTHER; PTHR47971; KINESIN-RELATED PROTEIN 6; 1.
DR Pfam; PF00225; Kinesin; 1.
DR PRINTS; PR00380; KINESINHEAVY.
DR SMART; SM00129; KISc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF47769; SAM/Pointed domain; 1.
DR PROSITE; PS00411; KINESIN_MOTOR_1; 1.
DR PROSITE; PS50067; KINESIN_MOTOR_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00283}; Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Motor protein {ECO:0000256|PROSITE-ProRule:PRU00283};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00283}; Reference proteome {ECO:0000313|Proteomes:UP000053872}.
FT DOMAIN 220..543
FT /note="Kinesin motor"
FT /evidence="ECO:0000259|PROSITE:PS50067"
FT REGION 108..140
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 555..633
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 653..692
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 882..925
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1050..1069
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1197..1219
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1247..1280
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 112..128
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 555..577
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 607..633
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 660..679
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 882..900
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 901..925
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1248..1269
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 310..317
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00283"
SQ SEQUENCE 1429 AA; 159359 MW; A58AB5D3E88D4768 CRC64;
MASCLYECLC EAELEKYYPH FAAFGLQKID ELAKVSMKDY TKLGVHDMND RKRLFQLIRI
IKIMQEDDVA CLSKQDFQPS DLFIQPQVTR SGPRRQLRFE SFFEENDSTV KDSESQSCGS
SDFSANEEKN SGGEMLGHIQ PHDSELIRLT RRDLNTPATC TRKDLSCPTV SDDIASLLGD
SEAPIIQRIT HISGYNYGLP RSCARPSTSE KDTPWTESEK IRVCVRKRPL GLREERRGEV
NIITVKDKET LLLHEKKEAV DLTQYILQHV FYFDEVFGES CTNQDVYMKT AHPLIQHIFN
GGNATCFAYG QTGAGKTYTM IGTHRNPGLY ALAAKDIFGH LEASQSRKDL HVLISFYEIY
CGQLYDLLNG RKRLFAREDG KHIVQIVGLR EVQVDSVDLL LEVILKGGKE RSTGATGVNS
DSSRSHAIIQ IQIKDAANRT FGRISFIDLA GSERAADARD SDRQTKMEGA EINQSLLALK
ECIRALDQEH AHTPFRQSKL TQVLKDSFIG NSKTCMIANV SPSHTATEHT LNTLRYADRV
KELKKGIKCS TPVTKRRRTA GNVSPKCVQN SHSLPPGEKS SPKKVKPGLQ HPSSATKTKA
CPAALQPPSV SFSSTHRGIN KGHSYKGNAS SPWFHHTSPV KGVLWVAHPL KKKADDLSTQ
SEKNPTTKDL TIKNAATAET KESGQRDKHM QDRPPVQCLK VQTVQPVQKQ LVSRDDTSFG
DGNLPSNGRQ EWGNVFAKQC VETWTNVPPF QKEREEHLRL YHQQFQQPPI LQQKLNYQPL
ERFLTEYKPQ EIQVKPELSV TPTELQSKEG MQLEDLDDSD FSEDSFSPVC SQSVKSRNTN
KCSQHSFFLH QREIETEEEQ KGQKRQDLFF KYAVPMQEHE LDDSWDYSEG SPKREESIKN
SGCSKTPSEW SYDLTTEPSP SNTAEKPYCL QEDPACNWKN GKDFLADNKQ YKSKHRSLVY
SSEATLTPEK DAPNTYVSPV LKSGMSDCKE VDLQHKEKEQ SPLDRQAALA GDKKLKVQKD
GFNHCGSSSC SPEFTPELTA PLPVSVLDYE ETTDTEKVSS NPEKSPPVKQ MLDRNVHGCQ
NRFEDEGWQC TRSRALTDSM LDLGEQTRRG GRHCARLHSP QSGDKWLSPT CCGVKPCCCL
LGPGPSKQGA AHRLFVGRDL METSAAESTG SRGEREGGLF LSNPMCKEYS AGRQCDADVK
NSTGNSGKSN SNQGPSLEPT AQEINADIPE KSYFPGVPCF VSVGNMDDAV PSPSQESSLL
SQPKSGPRNE DFSYSDDPAK SSLSNEEIAL LKNKLMQSTF TQETFAVHSG SVTKDNKLLA
NAKSLSGMSN GSSPSATSEV GKWQREALEK AQQAVIWAHQ QQLDEMASLC FKEECLINQM
SAMDFQSFVT KLDEVLVLKS KCIQTARAHL QPYLASPGTD MSPQTSPPV
//
