ID A0A2I0LM09_COLLI Unreviewed; 471 AA.
AC A0A2I0LM09;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=Keratin, type I cytoskeletal 19 {ECO:0000313|EMBL:PKK18451.1};
GN ORFNames=A306_00012797 {ECO:0000313|EMBL:PKK18451.1};
OS Columba livia (Rock dove).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Columbiformes; Columbidae; Columba.
OX NCBI_TaxID=8932 {ECO:0000313|EMBL:PKK18451.1, ECO:0000313|Proteomes:UP000053872};
RN [1] {ECO:0000313|EMBL:PKK18451.1, ECO:0000313|Proteomes:UP000053872}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC TISSUE=Blood {ECO:0000313|EMBL:PKK18451.1};
RX PubMed=23371554; DOI=10.1126/science.1230422;
RA Shapiro M.D., Kronenberg Z., Li C., Domyan E.T., Pan H., Campbell M.,
RA Tan H., Huff C.D., Hu H., Vickrey A.I., Nielsen S.C., Stringham S.A.,
RA Hu H., Willerslev E., Gilbert M.T., Yandell M., Zhang G., Wang J.;
RT "Genomic diversity and evolution of the head crest in the rock pigeon.";
RL Science 339:1063-1067(2013).
CC -!- SIMILARITY: Belongs to the intermediate filament family.
CC {ECO:0000256|RuleBase:RU000685}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PKK18451.1}.
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DR EMBL; AKCR02000201; PKK18451.1; -; Genomic_DNA.
DR RefSeq; XP_005513422.1; XM_005513365.1.
DR AlphaFoldDB; A0A2I0LM09; -.
DR STRING; 8932.A0A2I0LM09; -.
DR InParanoid; A0A2I0LM09; -.
DR Proteomes; UP000053872; Unassembled WGS sequence.
DR GO; GO:0005882; C:intermediate filament; IEA:UniProtKB-KW.
DR GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR Gene3D; 1.20.5.170; -; 1.
DR Gene3D; 1.20.5.500; Single helix bin; 1.
DR Gene3D; 1.20.5.1160; Vasodilator-stimulated phosphoprotein; 1.
DR InterPro; IPR018039; IF_conserved.
DR InterPro; IPR039008; IF_rod_dom.
DR InterPro; IPR002957; Keratin_I.
DR PANTHER; PTHR23239; INTERMEDIATE FILAMENT; 1.
DR PANTHER; PTHR23239:SF368; KERATIN, TYPE I CYTOSKELETAL 14; 1.
DR Pfam; PF00038; Filament; 1.
DR PRINTS; PR01248; TYPE1KERATIN.
DR SMART; SM01391; Filament; 1.
DR SUPFAM; SSF64593; Intermediate filament protein, coiled coil region; 2.
DR PROSITE; PS00226; IF_ROD_1; 1.
DR PROSITE; PS51842; IF_ROD_2; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Intermediate filament {ECO:0000256|ARBA:ARBA00022754,
KW ECO:0000256|RuleBase:RU000685};
KW Reference proteome {ECO:0000313|Proteomes:UP000053872}.
FT DOMAIN 117..429
FT /note="IF rod"
FT /evidence="ECO:0000259|PROSITE:PS51842"
FT REGION 16..37
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 431..471
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 114..148
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 287..407
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 444..459
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 471 AA; 51988 MW; B9549DA1C9C7D66E CRC64;
MSCAVRQVVT ACSQGRSSAG SSAAGSARKV SSSSSGRHAA YDFGGAVVNF SGDSLSEGLL
GKQLSAGSAA GGSFGVTQRA CSTLGFGGGG ICARGVGGGF TRASAGCGDG ILFANNEKAT
MQNLNDRLAS YLDKVRLLEG DNADLECKIR EWYAKVGPSC EPRDYSCFHK EIEDLQNQIL
CAAMETNKIL LSIDNNRMTA DDFRVKYETE CGLRQNVDAD ICNLRPVLDQ LASCKTDLQL
QCEALTEEMC CLKTNHEEEM SCLRKQATGD VSVEVNACPG PDLRKILEDL RCQYETLMER
NRKETEQWYA CKAEEVNLEV VTSSQEIESS NKQVTELRRQ LQALEINVQA QLTMKENLES
SLAETECRYN KYLSELQSQI SCVEQRLAEI RAEMECQNQE YKTLLDVKCR LEQEIQTYHC
LLEGGQQDIM YEPRDGGQRS PRNGCWKKQW TQSQPVPALP ALSSRPARSP Q
//
