ID A0A2I0LMI4_COLLI Unreviewed; 472 AA.
AC A0A2I0LMI4;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 24-JAN-2024, entry version 17.
DE SubName: Full=Keratin, type II cytoskeletal cochleal-like {ECO:0000313|EMBL:PKK18645.1};
GN ORFNames=A306_00012910 {ECO:0000313|EMBL:PKK18645.1};
OS Columba livia (Rock dove).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Columbiformes; Columbidae; Columba.
OX NCBI_TaxID=8932 {ECO:0000313|EMBL:PKK18645.1, ECO:0000313|Proteomes:UP000053872};
RN [1] {ECO:0000313|EMBL:PKK18645.1, ECO:0000313|Proteomes:UP000053872}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC TISSUE=Blood {ECO:0000313|EMBL:PKK18645.1};
RX PubMed=23371554; DOI=10.1126/science.1230422;
RA Shapiro M.D., Kronenberg Z., Li C., Domyan E.T., Pan H., Campbell M.,
RA Tan H., Huff C.D., Hu H., Vickrey A.I., Nielsen S.C., Stringham S.A.,
RA Hu H., Willerslev E., Gilbert M.T., Yandell M., Zhang G., Wang J.;
RT "Genomic diversity and evolution of the head crest in the rock pigeon.";
RL Science 339:1063-1067(2013).
CC -!- SIMILARITY: Belongs to the intermediate filament family.
CC {ECO:0000256|RuleBase:RU000685}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PKK18645.1}.
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DR EMBL; AKCR02000190; PKK18645.1; -; Genomic_DNA.
DR RefSeq; XP_013226670.1; XM_013371216.1.
DR AlphaFoldDB; A0A2I0LMI4; -.
DR STRING; 8932.A0A2I0LMI4; -.
DR InParanoid; A0A2I0LMI4; -.
DR Proteomes; UP000053872; Unassembled WGS sequence.
DR GO; GO:0045095; C:keratin filament; IEA:InterPro.
DR Gene3D; 1.20.5.170; -; 1.
DR Gene3D; 1.20.5.500; Single helix bin; 1.
DR Gene3D; 1.20.5.1160; Vasodilator-stimulated phosphoprotein; 1.
DR InterPro; IPR018039; IF_conserved.
DR InterPro; IPR039008; IF_rod_dom.
DR InterPro; IPR032444; Keratin_2_head.
DR InterPro; IPR003054; Keratin_II.
DR PANTHER; PTHR45616; GATA-TYPE DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR45616:SF21; KERATIN, TYPE II CYTOSKELETAL 7; 1.
DR Pfam; PF00038; Filament; 1.
DR Pfam; PF16208; Keratin_2_head; 1.
DR PRINTS; PR01276; TYPE2KERATIN.
DR SMART; SM01391; Filament; 1.
DR SUPFAM; SSF64593; Intermediate filament protein, coiled coil region; 2.
DR PROSITE; PS00226; IF_ROD_1; 1.
DR PROSITE; PS51842; IF_ROD_2; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Intermediate filament {ECO:0000256|ARBA:ARBA00022754,
KW ECO:0000256|RuleBase:RU000685};
KW Reference proteome {ECO:0000313|Proteomes:UP000053872}.
FT DOMAIN 153..464
FT /note="IF rod"
FT /evidence="ECO:0000259|PROSITE:PS51842"
FT REGION 66..108
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 206..289
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 408..442
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 472 AA; 51986 MW; 0E7F82DC3DBEB796 CRC64;
MLSSSHPSHH VHFVEVSRSL ALFSMQIKGR RCCSVVRGAA PEPVALPRNH RSSSAASCHR
GAAVGNRGPG CSSSGSLDGC RPAGAAGRRP PPRRGYGVGA AGAGGGSRSA GFGCRAGGAS
RPRTITPVTI NEQLLQPLCL QLDANVHAVK HQETEQIKTL NNKFASFIDK VRLLEQQNKV
LETKWSFLQA QKRPGRSAVP ALQAFIAHLK EQLEALGCDR ARLETDLKAA QQQLENNRKM
YKDERSRRPR TDSQFVALKK DAGCFFLNKA ELEAKLESLK EEVGFLRTFY EEETRQLRAN
VSEPSVVLQM DNSRDLDLGG VAADVRAQYE DIARRSRAEA QAWHESKFEE LRVTAGRNAA
SLQETKTKIA ELTRSIQTLS RGLCGAKDQR RRLEDALAAA EQRGGAAVQD AKRKLSELQT
ALQRSRAELA RQLRDCQQLS SARLGLDIEI VTYKKLLEGE ESRWVTAQGC TW
//
