GenomeNet

Database: UniProt
Entry: A0A2I0LNL5_COLLI
LinkDB: A0A2I0LNL5_COLLI
Original site: A0A2I0LNL5_COLLI 
ID   A0A2I0LNL5_COLLI        Unreviewed;      2664 AA.
AC   A0A2I0LNL5;
DT   28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT   28-FEB-2018, sequence version 1.
DT   16-JAN-2019, entry version 6.
DE   SubName: Full=Inositol 1,4,5-trisphosphate receptor, type 3 {ECO:0000313|EMBL:PKK19022.1};
GN   Name=ITPR3 {ECO:0000313|EMBL:PKK19022.1};
GN   ORFNames=A306_00013402 {ECO:0000313|EMBL:PKK19022.1};
OS   Columba livia (Rock dove).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Columbiformes; Columbidae; Columba.
OX   NCBI_TaxID=8932 {ECO:0000313|EMBL:PKK19022.1, ECO:0000313|Proteomes:UP000053872};
RN   [1] {ECO:0000313|EMBL:PKK19022.1, ECO:0000313|Proteomes:UP000053872}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   TISSUE=Blood {ECO:0000313|EMBL:PKK19022.1};
RX   PubMed=23371554; DOI=10.1126/science.1230422;
RA   Shapiro M.D., Kronenberg Z., Li C., Domyan E.T., Pan H., Campbell M.,
RA   Tan H., Huff C.D., Hu H., Vickrey A.I., Nielsen S.C., Stringham S.A.,
RA   Hu H., Willerslev E., Gilbert M.T., Yandell M., Zhang G., Wang J.;
RT   "Genomic diversity and evolution of the head crest in the rock
RT   pigeon.";
RL   Science 339:1063-1067(2013).
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:PKK19022.1}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   -----------------------------------------------------------------------
DR   EMBL; AKCR02000169; PKK19022.1; -; Genomic_DNA.
DR   RefSeq; XP_013226346.1; XM_013370892.1.
DR   GeneID; 102098742; -.
DR   KEGG; clv:102098742; -.
DR   CTD; 3710; -.
DR   KO; K04960; -.
DR   OrthoDB; 94996at2759; -.
DR   Proteomes; UP000053872; Unassembled WGS sequence.
DR   GO; GO:0005783; C:endoplasmic reticulum; IEA:InterPro.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0070679; F:inositol 1,4,5 trisphosphate binding; IEA:InterPro.
DR   GO; GO:0005220; F:inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity; IEA:InterPro.
DR   InterPro; IPR014821; Ins145_P3_rcpt.
DR   InterPro; IPR000493; InsP3_rcpt.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR036300; MIR_dom_sf.
DR   InterPro; IPR016093; MIR_motif.
DR   InterPro; IPR013662; RIH_assoc-dom.
DR   InterPro; IPR000699; RIH_dom.
DR   InterPro; IPR015925; Ryanodine_recept-rel.
DR   InterPro; IPR035910; RyR/IP3R_RIH_dom_sf.
DR   PANTHER; PTHR13715; PTHR13715; 1.
DR   Pfam; PF08709; Ins145_P3_rec; 1.
DR   Pfam; PF00520; Ion_trans; 1.
DR   Pfam; PF02815; MIR; 1.
DR   Pfam; PF08454; RIH_assoc; 1.
DR   Pfam; PF01365; RYDR_ITPR; 2.
DR   PRINTS; PR00779; INSP3RECEPTR.
DR   SMART; SM00472; MIR; 4.
DR   SUPFAM; SSF100909; SSF100909; 2.
DR   SUPFAM; SSF82109; SSF82109; 2.
DR   PROSITE; PS50919; MIR; 5.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000053872};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Receptor {ECO:0000313|EMBL:PKK19022.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000053872};
KW   Repeat {ECO:0000256|SAAS:SAAS00903904};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2198   2223       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2235   2253       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2265   2288       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2321   2346       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2366   2388       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2491   2514       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN      113    173       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      174    224       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      232    288       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      295    372       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      378    434       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   COILED       90    110       {ECO:0000256|SAM:Coils}.
FT   COILED     2622   2649       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   2664 AA;  304715 MW;  D986460AD5B9A89F CRC64;
     MNEMSSFLHI GDIVSLYAEG SVNGFISTLG LVDDRCVVEP AAGDLDNPPK KFRDCLFKVC
     PMNRYSAQKQ YWKAKQTKQD KEKIADVVLL QKLQHAAQME QKQNETENKK VHGDVVKYGS
     VIQLLHMKSN KYLTVNKRLP ALLEKNAMRV TLDATGNEGS WLFIQPFWKL RSNGDNVVVG
     DKVILNPVNA GQPLHASNYE LADNAGCKEV NSVNCNTSWK INLFMQFCDH MEEVLKGGDV
     VRLFHAEQEK FLTCDEYKGK LHVFLRTTLR QSATSATSSN ALWEVEVVHH DPCRGGAGHW
     NGLYRFKHLA TGNYLAAEEN PSYKGDVAEP KAAPTGGSGR ASRRNTGEKI KYRLVAVPHG
     NDIASLFELD PTTLQKTDSF VPRNSYVRLR HLCTNTWIQS TYVPIDIDEE RPIRLMLGTC
     PTKEDKEAFA IVSVPVSEIR DLDFANDASS MLASVVEKMN EGFLSQNDRR FVIQLLEDLV
     FFVSDVPNNG QNVLDIVVTK PNRERQKLMR EQNILKQIFG ILKAPFKDKG GEGPLVRLEE
     LSDQKNAPYQ YMFRLCYRVL RHSQEDYRKN QEHIAKQFGM MQSQIGYDIL AEDTITALLH
     NNRKLLEKHI TKTEVETFVS LVRKNREPRF LDYLSDLCVS NHIAIPVTQE LICKCVLDPK
     NSDILIKTEL RPVKEMSQSH EYLSIEYSEE EVWLTWTDKN NDHHEKSIRQ LAQEARAGNA
     HDENVLSYYR YQLKLFARMC LDRQYLAIKE ISQQLGVDLI FLCMADEMLP FDLRASFCHL
     MLHVHVDRDP QELVMPVKFA RLWTEIPTAI TIKDYDSNLN VSRDDKKNKF ASTMEFVEDY
     LNNVVSEAVP FANEEKNKLT FEVVSLAHNL IYFGFYSFSE LLRLTRTLLG IIDCVQNPQL
     MMQTVYNDEV TGKNVRRSIQ GVGQMMSTMV LSRKQSIFSS PNLSAGSAPE QVDRGRSIEN
     ENIVVMETKL KILEILQFIL NVRLDYRISY LLSVFKKEFV EVYPMQDSAA DGTAPAFDST
     TAAMNLERIG EHAEAMFGVG KTSSMLEVDD EGGRMFLRVL IHLTMHDYPP LISGSLQLLF
     KHFSQRQEVL HTFKQVQLLI SAQDVENYKV IKSELDKLRT MVEKSELWVD KKGSSKGDSA
     VEGNKKEKKE LAADEEVIAP GEKSSENYQI VKGILERLNK MCGVGEQVRK KQQRLLKNMD
     AHKVMLDLLQ IPYEKGDAKM MEILKFTHQF LQKFCAGNQE NQALLHKHLN LFLTPGLLEA
     ETMQHIFLNN YQLCSEINET VPQHFIHCVA THGRHVQYLD FLHTIIKAEG KYVKKCQDMI
     MTELTNAGDD VVVFYNDKAS LATLLEMMTA ARDGVEENSP LMYHISLVDL LAACAEGKNV
     YTEIKCTSLL PLEDVVRVVT HEDCITEVKM AYVNFVNHCY VDTEVEMKEI YTSNHIWTLF
     ENFTLDMAQM CKKREKRLPD PTLEKYVLTV VLDTINAFFS SPFSENSTSL QTHQTIVVQL
     LQSTTRLLEC PWLQQQHRSA VEACIRTLAM VAKSRSIALP MDLDAHVSSL LNSSSTSTVQ
     RNTSSYKTAT RTFPRVSTTP NQWDYKNIIE KLQDIITALE DRLKPLVEAE LSVLVDVLHR
     PELLFMEGTE AFQRCESGGF LSKLVQHTKD LMETEEKLCI KVLRTLQQML VKRNRYGERG
     NLLRKMLLNN YLQNKKSSSK GEIVDAAGGG QDQDWSAIAA VQCRLDREGA TKLVADLIMN
     TKNEKIFQES ILLAIRLLDG GNTEIQKSFY NLMTSDKKSE KFFKVLHDRM KKAQQETKST
     VSVNMSDIGN KPREDKDEHD PGTKGREDTF LMPGTPSRYP IALGFRKGHD TGEQGQNNEM
     GVTVLIMEPI LRFLQLLCEN HNRDLQNFLR CQNNKTNYNL VCETLQFLDI MCGSTTGGLG
     LLGLYINEYN VALITQTLET LTEYCQGPCH ENQSCIVTHE SNGIDIITAL ILNDISPLCK
     YRMDLVLQLK DNASKLLLAL MESRHDSENA ERILISLRPQ ELVDVIKKAY LQEEECENAE
     VSPREVGHNI YILALQLSRH NKSLQQLLKP VKRIQEEEEE GISSMLSLNN KQLTQMLKST
     APVQEEEEDP LAYYEKHTSQ IEIVRLDRSM EQIIFPVPGI CEFLTKETKY RLFTTTEQDE
     QGSKVSDFFD QSSFLHNEME WQKKLRSMPL MYWFSRRMTL WGSISFNLAV FINIIIAFFY
     PYVEATSMGV LDSPLISLLF WILICFSIMA LFTKRYGVRP LLVALILRSI YYLGIGLTLN
     ILGALNLANK IVFVVSFVGN RGTFIRGYKA MIMDVEFLYH VGYILTSVLG LFVHELFYSI
     LLFDLIYREE TLFNVIKSVT RNGRSILLTA LLALILVYLF SIVGFLFLKD DFILEVDRLP
     ASKATDDPLG MHRNMETFME SCSGDKISCS AVPTALEETA AEQWERACDT LLMCIVTVLN
     HGLRNGGGVG DILRKPSKDE SLFPARVVYD LLFFFIVIII VLNLIFGVII DTFADLRSEK
     QKKEEILKTT CFICGLERDK FDNKTVSFEE HIKYEHNMWN YLYFIVLVRV KNKTDYTGPE
     SYVAQMIKNK NLDWFPRMRA MSLVSNEGEG EQNEIRNLQD KLNTTMKLVS HLTSQLNELK
     EQMTEQRKRR QRMGFVDVQN TMNH
//
DBGET integrated database retrieval system