ID A0A2I0LQN8_COLLI Unreviewed; 583 AA.
AC A0A2I0LQN8;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 24-JAN-2024, entry version 22.
DE SubName: Full=Protocadherin gamma-A2-like {ECO:0000313|EMBL:PKK19746.1};
GN ORFNames=A306_00012412 {ECO:0000313|EMBL:PKK19746.1};
OS Columba livia (Rock dove).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Columbiformes; Columbidae; Columba.
OX NCBI_TaxID=8932 {ECO:0000313|EMBL:PKK19746.1, ECO:0000313|Proteomes:UP000053872};
RN [1] {ECO:0000313|EMBL:PKK19746.1, ECO:0000313|Proteomes:UP000053872}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC TISSUE=Blood {ECO:0000313|EMBL:PKK19746.1};
RX PubMed=23371554; DOI=10.1126/science.1230422;
RA Shapiro M.D., Kronenberg Z., Li C., Domyan E.T., Pan H., Campbell M.,
RA Tan H., Huff C.D., Hu H., Vickrey A.I., Nielsen S.C., Stringham S.A.,
RA Hu H., Willerslev E., Gilbert M.T., Yandell M., Zhang G., Wang J.;
RT "Genomic diversity and evolution of the head crest in the rock pigeon.";
RL Science 339:1063-1067(2013).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PKK19746.1}.
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DR EMBL; AKCR02000136; PKK19746.1; -; Genomic_DNA.
DR RefSeq; XP_013222772.1; XM_013367318.1.
DR AlphaFoldDB; A0A2I0LQN8; -.
DR GeneID; 102089056; -.
DR KEGG; clv:102089056; -.
DR InParanoid; A0A2I0LQN8; -.
DR OrthoDB; 5320041at2759; -.
DR Proteomes; UP000053872; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:InterPro.
DR GO; GO:0005509; F:calcium ion binding; IEA:UniProtKB-UniRule.
DR GO; GO:0007156; P:homophilic cell adhesion via plasma membrane adhesion molecules; IEA:InterPro.
DR CDD; cd11304; Cadherin_repeat; 5.
DR Gene3D; 2.60.40.60; Cadherins; 5.
DR InterPro; IPR002126; Cadherin-like_dom.
DR InterPro; IPR015919; Cadherin-like_sf.
DR InterPro; IPR032455; Cadherin_C.
DR InterPro; IPR020894; Cadherin_CS.
DR InterPro; IPR013164; Cadherin_N.
DR PANTHER; PTHR24028; CADHERIN-87A; 1.
DR PANTHER; PTHR24028:SF234; PROTOCADHERIN GAMMA-A3; 1.
DR Pfam; PF00028; Cadherin; 3.
DR Pfam; PF08266; Cadherin_2; 1.
DR Pfam; PF16492; Cadherin_C_2; 1.
DR PRINTS; PR00205; CADHERIN.
DR SMART; SM00112; CA; 4.
DR SUPFAM; SSF49313; Cadherin-like; 5.
DR PROSITE; PS00232; CADHERIN_1; 2.
DR PROSITE; PS50268; CADHERIN_2; 4.
PE 4: Predicted;
KW Calcium {ECO:0000256|ARBA:ARBA00022837, ECO:0000256|PROSITE-
KW ProRule:PRU00043}; Cell adhesion {ECO:0000256|ARBA:ARBA00022889};
KW Membrane {ECO:0000256|ARBA:ARBA00022989};
KW Reference proteome {ECO:0000313|Proteomes:UP000053872};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}; Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT SIGNAL 1..29
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 30..583
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5014157041"
FT DOMAIN 74..133
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 134..242
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 243..347
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 355..452
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT REGION 547..583
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 553..567
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 583 AA; 63684 MW; 1F8A9D2094877018 CRC64;
MWAAGRRWGR RERALLWGVL VAAWEATWGQ LRYSVPEEMP KGSFVGDVAK DLGLQLPALR
DRGVRVVSEG RTQYFALHGK TGHLVTTERI DREQLCRQLE KCVLRCEVVL EGDMQVHEIE
VEITDINDNS PSFKEMYLEE RMSETTDPGS RFPLTEAHDP DSGQNSVQIY ELSGDEHFSL
AVQTGPGGDQ RPELVLAKAL DREEAAFHEL VLRASDGGEP ARTGTARIRV AVLDANDNAP
VFSQAEYTVR VPEDVPVGST IVIVTATDAD EGLNGCIKYS LKKATDLASE IFHLDVETGA
IALVRSLDFE EGDTYEMDVQ ARDSGGLFDT AKVTITVTDV NDNAPKISVR SSLSEISEDA
QSGTVVALLH VQDRDSGANG EVRCSLDGDV PFLLRSSRGS YYSVVTAREL DREQVSEYNV
TVRAADGGSP ALWSSAVLWL RVLDVNDNAP VFAEARYSAR LPENNAAGVL VLRVRAWDAD
WGQNARVRYR LGEGRLLAAG SGALRGVPAS HFVGIDGVRA FLHSYSHEVS LTADSRKSQL
RFSGASCCDT LPARPPPDEP APLLGEDPAA PPRQHSQVLL RIP
//
