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Database: UniProt
Entry: A0A2I0LTI8_COLLI
LinkDB: A0A2I0LTI8_COLLI
Original site: A0A2I0LTI8_COLLI 
ID   A0A2I0LTI8_COLLI        Unreviewed;       589 AA.
AC   A0A2I0LTI8;
DT   28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT   28-FEB-2018, sequence version 1.
DT   31-JUL-2019, entry version 8.
DE   SubName: Full=Epsin 2, transcript variant X1 {ECO:0000313|EMBL:PKK20737.1};
GN   Name=EPN2 {ECO:0000313|EMBL:PKK20737.1};
GN   ORFNames=A306_00010492 {ECO:0000313|EMBL:PKK20737.1};
OS   Columba livia (Rock dove).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Columbiformes; Columbidae; Columba.
OX   NCBI_TaxID=8932 {ECO:0000313|EMBL:PKK20737.1, ECO:0000313|Proteomes:UP000053872};
RN   [1] {ECO:0000313|EMBL:PKK20737.1, ECO:0000313|Proteomes:UP000053872}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   TISSUE=Blood {ECO:0000313|EMBL:PKK20737.1};
RX   PubMed=23371554; DOI=10.1126/science.1230422;
RA   Shapiro M.D., Kronenberg Z., Li C., Domyan E.T., Pan H., Campbell M.,
RA   Tan H., Huff C.D., Hu H., Vickrey A.I., Nielsen S.C., Stringham S.A.,
RA   Hu H., Willerslev E., Gilbert M.T., Yandell M., Zhang G., Wang J.;
RT   "Genomic diversity and evolution of the head crest in the rock
RT   pigeon.";
RL   Science 339:1063-1067(2013).
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:PKK20737.1}.
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DR   EMBL; AKCR02000102; PKK20737.1; -; Genomic_DNA.
DR   RefSeq; XP_005504515.1; XM_005504458.1.
DR   GeneID; 102095449; -.
DR   KEGG; clv:102095449; -.
DR   CTD; 22905; -.
DR   KO; K12471; -.
DR   Proteomes; UP000053872; Unassembled WGS sequence.
DR   GO; GO:0030128; C:clathrin coat of endocytic vesicle; IEA:InterPro.
DR   GO; GO:0006897; P:endocytosis; IEA:InterPro.
DR   Gene3D; 1.25.40.90; -; 1.
DR   InterPro; IPR013809; ENTH.
DR   InterPro; IPR008942; ENTH_VHS.
DR   InterPro; IPR027319; Epsin-2_metazoa.
DR   InterPro; IPR003903; UIM_dom.
DR   PANTHER; PTHR12276:SF50; PTHR12276:SF50; 1.
DR   Pfam; PF01417; ENTH; 1.
DR   SMART; SM00273; ENTH; 1.
DR   SMART; SM00726; UIM; 2.
DR   SUPFAM; SSF48464; SSF48464; 1.
DR   PROSITE; PS50942; ENTH; 1.
DR   PROSITE; PS50330; UIM; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000053872};
KW   Reference proteome {ECO:0000313|Proteomes:UP000053872}.
FT   DOMAIN       12    144       ENTH. {ECO:0000259|PROSITE:PS50942}.
FT   REGION      161    218       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   REGION      279    378       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   REGION      403    450       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   REGION      570    589       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   COILED       10     30       {ECO:0000256|SAM:Coils}.
FT   COMPBIAS    300    314       Polar. {ECO:0000256|SAM:MobiDB-lite}.
FT   COMPBIAS    333    359       Polar. {ECO:0000256|SAM:MobiDB-lite}.
FT   COMPBIAS    406    444       Polar. {ECO:0000256|SAM:MobiDB-lite}.
SQ   SEQUENCE   589 AA;  63254 MW;  F7266DDE11D9F4EE CRC64;
     MTTSSIRRQM KNIVNNYSEA EIKVREATSN DPWGPSSSLM TEIADLTYNV VAFSEIMSMI
     WKRLNDHGKN WRHVYKALTL LDYLIKTGSE RVAQQCKENI FAIQTLKDFQ YIDRDGKDQG
     INVREKSKQL VSLLKDDERL KTERAQALKT KERMAQVATG VGSNQITFGR GSSQPNLSTS
     YSEQEYGKSG GSPASYHGST SPRVSSELEQ ARPQTSGEEE LQLQLALAMS REVAEQEERL
     RRGDDLRLQM ALEESRRDTI KIPKKKEHTT LLDLMDALPS SAPAPQKAEP WGPPAVANQT
     DPWGGSTVAA TASDPWQSFG AKPAASVDPW AAPAGSTAQS LSKNVDPWAP AQPSSTAAKP
     SVDPWGPAPA NKPLSTSGST SFDLFSNLNG TVKDDFSEFD TLRTSKKPAE SGSTLPSQHS
     GTTSPDLFDS QHSSATSGKQ SAARKTPESF LGPNAALVNL DSLVSKPPQP VTSLNPFLAP
     GAATAPTPIN PFQVNQPQPL TLNQMRASPV MGTSPSFSAV PPMSMEPIPL SSMAPVPVGM
     APIPAMGTLT RMGQGLNVSI AGSMTQPLHS TGIPPSASQA TNTTNPFLL
//
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