ID A0A2I0LTK6_COLLI Unreviewed; 454 AA.
AC A0A2I0LTK6;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 22-FEB-2023, entry version 16.
DE SubName: Full=Target of myb1 like 2 membrane trafficking protein, transcript variant X2 {ECO:0000313|EMBL:PKK20760.1};
GN Name=TOM1L2 {ECO:0000313|EMBL:PKK20760.1};
GN ORFNames=A306_00010510 {ECO:0000313|EMBL:PKK20760.1};
OS Columba livia (Rock dove).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Columbiformes; Columbidae; Columba.
OX NCBI_TaxID=8932 {ECO:0000313|EMBL:PKK20760.1, ECO:0000313|Proteomes:UP000053872};
RN [1] {ECO:0000313|EMBL:PKK20760.1, ECO:0000313|Proteomes:UP000053872}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC TISSUE=Blood {ECO:0000313|EMBL:PKK20760.1};
RX PubMed=23371554; DOI=10.1126/science.1230422;
RA Shapiro M.D., Kronenberg Z., Li C., Domyan E.T., Pan H., Campbell M.,
RA Tan H., Huff C.D., Hu H., Vickrey A.I., Nielsen S.C., Stringham S.A.,
RA Hu H., Willerslev E., Gilbert M.T., Yandell M., Zhang G., Wang J.;
RT "Genomic diversity and evolution of the head crest in the rock pigeon.";
RL Science 339:1063-1067(2013).
CC -!- SIMILARITY: Belongs to the TOM1 family. {ECO:0000256|ARBA:ARBA00007708,
CC ECO:0000256|PIRNR:PIRNR036948}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PKK20760.1}.
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DR EMBL; AKCR02000102; PKK20760.1; -; Genomic_DNA.
DR RefSeq; XP_005504535.1; XM_005504478.1.
DR AlphaFoldDB; A0A2I0LTK6; -.
DR GeneID; 102098408; -.
DR KEGG; clv:102098408; -.
DR CTD; 146691; -.
DR OrthoDB; 609735at2759; -.
DR Proteomes; UP000053872; Unassembled WGS sequence.
DR GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR GO; GO:0043130; F:ubiquitin binding; IEA:InterPro.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-UniRule.
DR CDD; cd14238; GAT_TM1L2; 1.
DR Gene3D; 1.20.58.160; -; 1.
DR Gene3D; 1.25.40.90; -; 1.
DR InterPro; IPR008942; ENTH_VHS.
DR InterPro; IPR004152; GAT_dom.
DR InterPro; IPR038425; GAT_sf.
DR InterPro; IPR014645; TOM1.
DR InterPro; IPR002014; VHS_dom.
DR PANTHER; PTHR13856:SF31; TOM1-LIKE PROTEIN 2; 1.
DR PANTHER; PTHR13856; VHS DOMAIN CONTAINING PROTEIN FAMILY; 1.
DR Pfam; PF03127; GAT; 1.
DR Pfam; PF00790; VHS; 1.
DR PIRSF; PIRSF036948; TOM1; 1.
DR SMART; SM00288; VHS; 1.
DR SUPFAM; SSF48464; ENTH/VHS domain; 1.
DR SUPFAM; SSF89009; GAT-like domain; 1.
DR PROSITE; PS50909; GAT; 1.
DR PROSITE; PS50179; VHS; 1.
PE 3: Inferred from homology;
KW Protein transport {ECO:0000256|ARBA:ARBA00022927,
KW ECO:0000256|PIRNR:PIRNR036948};
KW Reference proteome {ECO:0000313|Proteomes:UP000053872};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|PIRNR:PIRNR036948}.
FT DOMAIN 1..119
FT /note="VHS"
FT /evidence="ECO:0000259|PROSITE:PS50179"
FT DOMAIN 186..274
FT /note="GAT"
FT /evidence="ECO:0000259|PROSITE:PS50909"
FT REGION 131..166
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 417..454
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 142..166
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 425..439
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 454 AA; 49857 MW; 8846A506850064FC CRC64;
MEICDIINET EEGPKDAIRA LKKRLNGNKN YREVMLALTV LETCVKNCGH RFHVLVANRD
FIDGVLVKII SPKNNPPTIV QDKVLALIQA WADAFRSSPD LTGVVHIYEE LKRKGIEFPM
ADLDALSPIH TPQRSVPEVD PAANMHNSQP QQRMSTGSYS SSSPTAYSAP QAPALNVIGP
ITANSEQIAR LRSELDIVRG NTKVMSEMLT EMVPGQEDSS DLELLQELNR TCRAMQQRIV
ELISRVSNEE VTEELLHVND DLNNVFLRYE RFERYRSGRS TQNASNGVLN EVTEDNLIDL
GPGSPAVVSP MVGNSAAPSS LSSQLAGLDL GTNSVSGTLS SLQHCNPRDD FDMFAQTRGS
SLAEQRKNVT YEDPQAVKGL ASALDVRKQN TGGKGEELEE GVTSEEFDKF LEERAKAAEM
VPNLPSPPVE APTPPANPPS RKKQERSEDA LFAL
//
