ID A0A2I0LYJ2_COLLI Unreviewed; 314 AA.
AC A0A2I0LYJ2;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Rabphilin 3A-like (Without C2 domains) {ECO:0000313|EMBL:PKK22493.1};
GN Name=RPH3AL {ECO:0000313|EMBL:PKK22493.1};
GN ORFNames=A306_00008039 {ECO:0000313|EMBL:PKK22493.1};
OS Columba livia (Rock dove).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Columbiformes; Columbidae; Columba.
OX NCBI_TaxID=8932 {ECO:0000313|EMBL:PKK22493.1, ECO:0000313|Proteomes:UP000053872};
RN [1] {ECO:0000313|EMBL:PKK22493.1, ECO:0000313|Proteomes:UP000053872}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC TISSUE=Blood {ECO:0000313|EMBL:PKK22493.1};
RX PubMed=23371554; DOI=10.1126/science.1230422;
RA Shapiro M.D., Kronenberg Z., Li C., Domyan E.T., Pan H., Campbell M.,
RA Tan H., Huff C.D., Hu H., Vickrey A.I., Nielsen S.C., Stringham S.A.,
RA Hu H., Willerslev E., Gilbert M.T., Yandell M., Zhang G., Wang J.;
RT "Genomic diversity and evolution of the head crest in the rock pigeon.";
RL Science 339:1063-1067(2013).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PKK22493.1}.
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DR EMBL; AKCR02000061; PKK22493.1; -; Genomic_DNA.
DR RefSeq; XP_005512004.1; XM_005511947.1.
DR AlphaFoldDB; A0A2I0LYJ2; -.
DR STRING; 8932.A0A2I0LYJ2; -.
DR GeneID; 102093951; -.
DR KEGG; clv:102093951; -.
DR CTD; 9501; -.
DR InParanoid; A0A2I0LYJ2; -.
DR OrthoDB; 590187at2759; -.
DR Proteomes; UP000053872; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0031267; F:small GTPase binding; IEA:InterPro.
DR GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR041282; FYVE_2.
DR InterPro; IPR010911; Rab_BD.
DR InterPro; IPR043566; Rabphilin/DOC2/Noc2.
DR InterPro; IPR017455; Znf_FYVE-rel.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR45729:SF4; RAB EFFECTOR NOC2; 1.
DR PANTHER; PTHR45729; RABPHILIN, ISOFORM A; 1.
DR Pfam; PF02318; FYVE_2; 1.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 1.
DR PROSITE; PS50916; RABBD; 1.
DR PROSITE; PS50178; ZF_FYVE; 1.
PE 4: Predicted;
KW Exocytosis {ECO:0000256|ARBA:ARBA00022483};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000053872};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00091}.
FT DOMAIN 41..158
FT /note="RabBD"
FT /evidence="ECO:0000259|PROSITE:PS50916"
FT DOMAIN 89..146
FT /note="FYVE-type"
FT /evidence="ECO:0000259|PROSITE:PS50178"
FT REGION 167..194
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 209..314
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 209..227
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 256..295
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 314 AA; 34227 MW; 34183A3D0B8A46EB CRC64;
MADTIFSSGT GQWVCPNDRQ LALRAKLQTG WSVHTFQTEK QRKMQALSPQ ELEVILEVIR
KAERLDIIEQ QRIGRLVERL ENMRKNTMGN GLSQCLLCGE LLGLLGSTSV FCQDCKKKVC
TKCGIETFGA QKRHLWLCKI CSEQREVWKR SGAWFYKGLP KYIKPLKSSG KSSEPPSQPW
QSEPAVPEAE SVGTSRSFTW ARGKVVSSDS ESDSEFSSSS LDDKSLPAGS RGSQGRKHRP
GLAPIREPSP AVGSVLGSAH SPTLSGSRSS LGSEQGAAPS AMESCQSNQP ADGCNSDAVS
RAPGKRSVHT RTRC
//
