ID A0A2I0LZH4_COLLI Unreviewed; 858 AA.
AC A0A2I0LZH4;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 13-SEP-2023, entry version 11.
DE SubName: Full=cAMP-regulated phosphoprotein, 21kDa, transcript variant X6 {ECO:0000313|EMBL:PKK22822.1};
DE SubName: Full=cAMP-regulated phosphoprotein, 21kDa, transcript variant X7 {ECO:0000313|EMBL:PKK22820.1};
GN Name=ARPP21 {ECO:0000313|EMBL:PKK22822.1};
GN ORFNames=A306_00011357 {ECO:0000313|EMBL:PKK22822.1};
OS Columba livia (Rock dove).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Columbiformes; Columbidae; Columba.
OX NCBI_TaxID=8932 {ECO:0000313|EMBL:PKK22822.1, ECO:0000313|Proteomes:UP000053872};
RN [1] {ECO:0000313|EMBL:PKK22822.1, ECO:0000313|Proteomes:UP000053872}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC TISSUE=Blood {ECO:0000313|EMBL:PKK22822.1};
RX PubMed=23371554; DOI=10.1126/science.1230422;
RA Shapiro M.D., Kronenberg Z., Li C., Domyan E.T., Pan H., Campbell M.,
RA Tan H., Huff C.D., Hu H., Vickrey A.I., Nielsen S.C., Stringham S.A.,
RA Hu H., Willerslev E., Gilbert M.T., Yandell M., Zhang G., Wang J.;
RT "Genomic diversity and evolution of the head crest in the rock pigeon.";
RL Science 339:1063-1067(2013).
RN [2] {ECO:0000313|EMBL:PKK22822.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Blood {ECO:0000313|EMBL:PKK22822.1};
RA Holt C., Campbell M., Edelman N., Keays D., Kapusta A., Domyan E., Suh A.,
RA Carleton J., Warren W., Yandell M., Gilbert M.T., Shapiro M.D.;
RT "Improved genome assembly and annotation for the rock pigeon (Columba
RT livia).";
RL Submitted (AUG-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PKK22822.1}.
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DR EMBL; AKCR02000057; PKK22820.1; -; Genomic_DNA.
DR EMBL; AKCR02000057; PKK22822.1; -; Genomic_DNA.
DR RefSeq; XP_005500077.1; XM_005500020.1.
DR RefSeq; XP_005500078.1; XM_005500021.1.
DR AlphaFoldDB; A0A2I0LZH4; -.
DR Proteomes; UP000053872; Unassembled WGS sequence.
DR GO; GO:0003676; F:nucleic acid binding; IEA:UniProtKB-UniRule.
DR CDD; cd02642; R3H_encore_like; 1.
DR Gene3D; 3.30.1370.50; R3H-like domain; 1.
DR InterPro; IPR001374; R3H_dom.
DR InterPro; IPR036867; R3H_dom_sf.
DR InterPro; IPR024771; SUZ.
DR PANTHER; PTHR15672:SF14; CAMP-REGULATED PHOSPHOPROTEIN 21; 1.
DR PANTHER; PTHR15672; CAMP-REGULATED PHOSPHOPROTEIN 21 RELATED R3H DOMAIN CONTAINING PROTEIN; 1.
DR Pfam; PF01424; R3H; 1.
DR Pfam; PF12752; SUZ; 1.
DR SMART; SM00393; R3H; 1.
DR SUPFAM; SSF82708; R3H domain; 1.
DR PROSITE; PS51061; R3H; 1.
DR PROSITE; PS51673; SUZ; 1.
PE 4: Predicted;
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000053872}.
FT DOMAIN 178..241
FT /note="R3H"
FT /evidence="ECO:0000259|PROSITE:PS51061"
FT DOMAIN 242..314
FT /note="SUZ"
FT /evidence="ECO:0000259|PROSITE:PS51673"
FT REGION 1..96
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 108..144
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 259..290
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 344..439
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 515..552
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 603..681
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 6..20
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 21..35
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 36..54
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 115..144
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 349..364
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 376..439
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 603..658
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 659..681
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 858 AA; 94953 MW; B6C12273616D6E4F CRC64;
MSEQGKLNEE TAEETAKEQE SALSEANPDN CILSKSESSE VEEKEEKLSD AKTELQKRGA
NQNQQKKRSK SGAKGKLVRS LAVCEETSPR PGAENLHDNQ ESIQLQLSSF PSLQEEDKSN
KDDSEKEKEK DKNKEKDKNS EKKIRMLSKD CSQEYTDSTG IDLHEFLINT LKNNPRDRMI
LLKMEQEIID FISDNNNHYK KFPQMSSYQR MLVHRVAAYF GMDHNVDQTG KSVIINKTSN
TRIPEQRFSE HLKDEKGEES QKRFILKRDN SSIDKEDNQQ NRILPFRDDR RSKSIEEREE
EYQRVRERIF AQDSVCSQEN LFVENSRLLE DSSICNETHK KRQLFRGNRD STGKASGSRQ
SSTENELKWA DHQRPWSSTD SDSSNRNLKP AITKTASFGG ITVLTRGDSS SSNRSTGKLS
KTGSSESSSS AGSSGSLSRI HQPLQSASLV PGVTASSSGN VSYPENGMSG QVAPSNTSYI
ILPLEAAGIP PGSILLNPHT GQPFVNPDGT PAIYNPPSGQ QTMRSQMVGQ SQQQPSSQQP
QQVQQPQPQM ASHLVTQPVQ AMQPSSQSVQ YPAVSYPPQH LLPVSPTQQF SVRDDMTTQF
NQMSLSRQSS GDNSESPSGP VYPSPLLQQP AQQPGYIMAS PSQQLPPGGF TGSGPPVSQQ
VLQPPPPPQG FVQQPPPPAQ MPVYYYPSGQ YPTSTTQQYR PIASVQYNAQ RSQQIPQTAQ
QAGYQPVLPN QQQGFQGLMG MQQPPQSQNL MNNQQGNQVQ GMMVQYPAMS SYQVPMTQGS
QGLPQQSYQQ PIMLPNQSGQ GTLTATGMPV YCNVIPPAPQ NNLRLIAPHC PSNNVPVISA
SCRTNCASIN NAGWQVKY
//
