ID A0A2I0M097_COLLI Unreviewed; 615 AA.
AC A0A2I0M097;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 24-JAN-2024, entry version 16.
DE RecName: Full=Kelch-like protein 36 {ECO:0000256|ARBA:ARBA00019802};
GN Name=KLHL36 {ECO:0000313|EMBL:PKK23102.1};
GN ORFNames=A306_00009684 {ECO:0000313|EMBL:PKK23102.1};
OS Columba livia (Rock dove).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Columbiformes; Columbidae; Columba.
OX NCBI_TaxID=8932 {ECO:0000313|EMBL:PKK23102.1, ECO:0000313|Proteomes:UP000053872};
RN [1] {ECO:0000313|EMBL:PKK23102.1, ECO:0000313|Proteomes:UP000053872}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC TISSUE=Blood {ECO:0000313|EMBL:PKK23102.1};
RX PubMed=23371554; DOI=10.1126/science.1230422;
RA Shapiro M.D., Kronenberg Z., Li C., Domyan E.T., Pan H., Campbell M.,
RA Tan H., Huff C.D., Hu H., Vickrey A.I., Nielsen S.C., Stringham S.A.,
RA Hu H., Willerslev E., Gilbert M.T., Yandell M., Zhang G., Wang J.;
RT "Genomic diversity and evolution of the head crest in the rock pigeon.";
RL Science 339:1063-1067(2013).
CC -!- FUNCTION: Probable substrate-specific adapter of an E3 ubiquitin-
CC protein ligase complex which mediates the ubiquitination and subsequent
CC proteasomal degradation of target proteins.
CC {ECO:0000256|ARBA:ARBA00003098}.
CC -!- PATHWAY: Protein modification; protein ubiquitination.
CC {ECO:0000256|ARBA:ARBA00004906}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PKK23102.1}.
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DR EMBL; AKCR02000054; PKK23102.1; -; Genomic_DNA.
DR RefSeq; XP_005504797.1; XM_005504740.1.
DR AlphaFoldDB; A0A2I0M097; -.
DR STRING; 8932.A0A2I0M097; -.
DR GeneID; 102084159; -.
DR KEGG; clv:102084159; -.
DR CTD; 79786; -.
DR InParanoid; A0A2I0M097; -.
DR OrthoDB; 5472491at2759; -.
DR UniPathway; UPA00143; -.
DR Proteomes; UP000053872; Unassembled WGS sequence.
DR GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR CDD; cd18475; BACK_KLHL36; 1.
DR CDD; cd18266; BTB_POZ_KLHL36; 1.
DR Gene3D; 1.25.40.420; -; 1.
DR Gene3D; 2.120.10.80; Kelch-type beta propeller; 1.
DR InterPro; IPR011705; BACK.
DR InterPro; IPR017096; BTB-kelch_protein.
DR InterPro; IPR000210; BTB/POZ_dom.
DR InterPro; IPR015915; Kelch-typ_b-propeller.
DR InterPro; IPR006652; Kelch_1.
DR InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR PANTHER; PTHR45632:SF4; KELCH-LIKE PROTEIN 36; 1.
DR PANTHER; PTHR45632; LD33804P; 1.
DR Pfam; PF07707; BACK; 1.
DR Pfam; PF00651; BTB; 1.
DR Pfam; PF01344; Kelch_1; 5.
DR PIRSF; PIRSF037037; Kelch-like_protein_gigaxonin; 1.
DR SMART; SM00875; BACK; 1.
DR SMART; SM00225; BTB; 1.
DR SMART; SM00612; Kelch; 6.
DR SUPFAM; SSF117281; Kelch motif; 1.
DR SUPFAM; SSF54695; POZ domain; 1.
DR PROSITE; PS50097; BTB; 1.
PE 4: Predicted;
KW Kelch repeat {ECO:0000256|ARBA:ARBA00022441};
KW Reference proteome {ECO:0000313|Proteomes:UP000053872};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786}.
FT DOMAIN 45..112
FT /note="BTB"
FT /evidence="ECO:0000259|PROSITE:PS50097"
SQ SEQUENCE 615 AA; 70281 MW; 35CC5EB4F8AA08D5 CRC64;
MEGTRQTRIC RPHKISESSK VYRWDDHSSL VLQSLNEQRH RGLFCDIVLV VDEQRVPAHR
NLLAVCSDYF NSMFTIGMRE AHQKEVELFG ASYIGLKAVV DFLYGSELSL DGGNIDYVLE
TAHLLQIWKV VDFCCEYLEN EVSEENYLYL QELASIYNLK RLDSYIDSFI LQNFGTLSFT
PDFLQNVSLQ KLCQYLDSSD VQQECEHDLL QAALQWLTQY PERENEAYQV LDNIHFPLIP
KSDLLHRVKP AVCSLLPKEA NCEGFIEEAV NYHNNVTAQP VLQNKRTALR TCEERLLFVG
GEVSERCLEL SDDTCFLDVR KGQWVAETPL PARRSHHCVA VLGGFIFIAG GSFSRDNGGD
AASNLLYRYD PRCNQWIKVA SMRQRRVDFY LGAITDMLVA VGGRNENGAL SSVETYSPQK
DSWSYIAGLP RFTYGHAGTV YKEFVYISGG HDYQIGPYRK NLLCYDYRTD VWEEKRPMIT
ARGWHSMCTL QDNIYSIGGS DDNIETMARF DILSVESYSP QCNQWTRVAP LLQANSESGV
AVWEGKIYIL GGYSWEETVF SKTVQVYDKE KNKWYKGTDL PKAIAGVSAC VCALKPKTED
KKKKKKTKKH QDRGR
//
