ID A0A2I0M247_COLLI Unreviewed; 500 AA.
AC A0A2I0M247;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 24-JAN-2024, entry version 16.
DE SubName: Full=Matrilin 4 {ECO:0000313|EMBL:PKK23754.1};
GN Name=MATN4 {ECO:0000313|EMBL:PKK23754.1};
GN ORFNames=A306_00008956 {ECO:0000313|EMBL:PKK23754.1};
OS Columba livia (Rock dove).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Columbiformes; Columbidae; Columba.
OX NCBI_TaxID=8932 {ECO:0000313|EMBL:PKK23754.1, ECO:0000313|Proteomes:UP000053872};
RN [1] {ECO:0000313|EMBL:PKK23754.1, ECO:0000313|Proteomes:UP000053872}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC TISSUE=Blood {ECO:0000313|EMBL:PKK23754.1};
RX PubMed=23371554; DOI=10.1126/science.1230422;
RA Shapiro M.D., Kronenberg Z., Li C., Domyan E.T., Pan H., Campbell M.,
RA Tan H., Huff C.D., Hu H., Vickrey A.I., Nielsen S.C., Stringham S.A.,
RA Hu H., Willerslev E., Gilbert M.T., Yandell M., Zhang G., Wang J.;
RT "Genomic diversity and evolution of the head crest in the rock pigeon.";
RL Science 339:1063-1067(2013).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PKK23754.1}.
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DR EMBL; AKCR02000047; PKK23754.1; -; Genomic_DNA.
DR RefSeq; XP_013222516.1; XM_013367062.1.
DR AlphaFoldDB; A0A2I0M247; -.
DR STRING; 8932.A0A2I0M247; -.
DR InParanoid; A0A2I0M247; -.
DR Proteomes; UP000053872; Unassembled WGS sequence.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR Gene3D; 1.20.5.30; -; 1.
DR Gene3D; 2.10.25.10; Laminin; 1.
DR Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 2.
DR InterPro; IPR001881; EGF-like_Ca-bd_dom.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR036337; Matrilin_cc_sf.
DR InterPro; IPR019466; Matrilin_coiled-coil_trimer.
DR InterPro; IPR002035; VWF_A.
DR InterPro; IPR036465; vWFA_dom_sf.
DR PANTHER; PTHR24020; COLLAGEN ALPHA; 1.
DR PANTHER; PTHR24020:SF14; MATRILIN-4; 1.
DR Pfam; PF14670; FXa_inhibition; 1.
DR Pfam; PF10393; Matrilin_ccoil; 1.
DR Pfam; PF00092; VWA; 2.
DR PRINTS; PR00453; VWFADOMAIN.
DR SMART; SM00181; EGF; 1.
DR SMART; SM00179; EGF_CA; 1.
DR SMART; SM01279; Matrilin_ccoil; 1.
DR SMART; SM00327; VWA; 2.
DR SUPFAM; SSF58002; Chicken cartilage matrix protein; 1.
DR SUPFAM; SSF53300; vWA-like; 2.
DR PROSITE; PS01186; EGF_2; 1.
DR PROSITE; PS50234; VWFA; 2.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW EGF-like domain {ECO:0000256|ARBA:ARBA00022536};
KW Reference proteome {ECO:0000313|Proteomes:UP000053872};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..500
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5014122338"
FT DOMAIN 36..215
FT /note="VWFA"
FT /evidence="ECO:0000259|PROSITE:PS50234"
FT DOMAIN 265..440
FT /note="VWFA"
FT /evidence="ECO:0000259|PROSITE:PS50234"
SQ SEQUENCE 500 AA; 55801 MW; 98F04C2FD8EB8793 CRC64;
MKLLPVAPLL LLLLMTLEAR PKPAGEPQPC RTGPMDIVFV IDSSRSVRPF EFETMRQFMM
DIIGSLDVGP NATRVGVIQY SSQVQNIFSL KTFFTRADME KAINSIVPLA QGTMTGLAIQ
YAMNVAFTTQ EGARPLHKKI PRIAIIVTDG RPQDRVTEVA TQARNAGIEI YAVGIQRADM
NSLRAMASPP LEEHVFLVES FELIQQFGKQ FQDKLCGVDM CVEREHGCQH SCISTPGSFY
CECNPGYRLN MDGRTCSQCG SGHVDLVMVI DGSKSVRPQN FELVKQFVNR IVDLLEVSPH
GTRVGLVQYS SRVRTEFPLN KYHSADEIKK AVMEVEYMEK GTMTGLALKH MVEHSFSELE
GARPLSHNVP RIGLVFTDGR SQDDISEWAR RAKESGIVMF AVGVGKAVEE ELRAIASEPV
EQHFSYSADF TTMTHLVENF KLNICPEESK GETEIRSPCE CEALVQFQTN TVAILQSLTE
KIAQMTARLE DLEKQIAKKK
//
