ID A0A2I0M3J1_COLLI Unreviewed; 681 AA.
AC A0A2I0M3J1;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 24-JAN-2024, entry version 20.
DE SubName: Full=Netrin G2, transcript variant X1 {ECO:0000313|EMBL:PKK24255.1};
GN Name=NTNG2 {ECO:0000313|EMBL:PKK24255.1};
GN ORFNames=A306_00005978 {ECO:0000313|EMBL:PKK24255.1};
OS Columba livia (Rock dove).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Columbiformes; Columbidae; Columba.
OX NCBI_TaxID=8932 {ECO:0000313|EMBL:PKK24255.1, ECO:0000313|Proteomes:UP000053872};
RN [1] {ECO:0000313|EMBL:PKK24255.1, ECO:0000313|Proteomes:UP000053872}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC TISSUE=Blood {ECO:0000313|EMBL:PKK24255.1};
RX PubMed=23371554; DOI=10.1126/science.1230422;
RA Shapiro M.D., Kronenberg Z., Li C., Domyan E.T., Pan H., Campbell M.,
RA Tan H., Huff C.D., Hu H., Vickrey A.I., Nielsen S.C., Stringham S.A.,
RA Hu H., Willerslev E., Gilbert M.T., Yandell M., Zhang G., Wang J.;
RT "Genomic diversity and evolution of the head crest in the rock pigeon.";
RL Science 339:1063-1067(2013).
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PKK24255.1}.
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DR EMBL; AKCR02000043; PKK24255.1; -; Genomic_DNA.
DR RefSeq; XP_013226058.1; XM_013370604.1.
DR AlphaFoldDB; A0A2I0M3J1; -.
DR STRING; 8932.A0A2I0M3J1; -.
DR InParanoid; A0A2I0M3J1; -.
DR Proteomes; UP000053872; Unassembled WGS sequence.
DR CDD; cd00055; EGF_Lam; 3.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR Gene3D; 2.10.25.10; Laminin; 4.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR008211; Laminin_N.
DR InterPro; IPR002049; LE_dom.
DR PANTHER; PTHR10574:SF27; NETRIN-G2; 1.
DR PANTHER; PTHR10574; NETRIN/LAMININ-RELATED; 1.
DR Pfam; PF00053; Laminin_EGF; 3.
DR Pfam; PF00055; Laminin_N; 1.
DR SMART; SM00180; EGF_Lam; 3.
DR SMART; SM00136; LamNT; 1.
DR SUPFAM; SSF57196; EGF/Laminin; 3.
DR PROSITE; PS00022; EGF_1; 1.
DR PROSITE; PS01186; EGF_2; 1.
DR PROSITE; PS50026; EGF_3; 1.
DR PROSITE; PS01248; EGF_LAM_1; 1.
DR PROSITE; PS50027; EGF_LAM_2; 1.
DR PROSITE; PS51117; LAMININ_NTER; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00076}; EGF-like domain {ECO:0000256|PROSITE-ProRule:PRU00076};
KW Laminin EGF-like domain {ECO:0000256|ARBA:ARBA00023292,
KW ECO:0000256|PROSITE-ProRule:PRU00460};
KW Reference proteome {ECO:0000313|Proteomes:UP000053872};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..17
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 18..681
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5014161212"
FT DOMAIN 35..286
FT /note="Laminin N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51117"
FT DOMAIN 564..608
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT DOMAIN 607..642
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT REGION 347..495
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 355..403
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 469..486
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT DISULFID 564..576
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 584..593
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 632..641
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
SQ SEQUENCE 681 AA; 75543 MW; FE6AC91812BA07E3 CRC64;
MLHLAALLLH CLPLAMGQYD ICKSWVTTDD GPSWEFYACQ PKAMRMKDYV TVRVDPAGIT
CGDPPERFCT HENPYLCSDE CDASNPDLAH PPKLMFDSED EGLATYWQSV TWRRYPEPLL
ANITLSWNKS IELTDDIVIT FEYGRPTIMM LEKSLDNGRT WHPYQYYADD CMEAFSMPAR
RVRDLSTTSA NRVLCTEEYS RWAGSKKEKT VRFEVRDRFA IFAGPDLKNM DNLYTRLESA
KGLKDFFTVT DLRMRLLRPA LGGTYVQREN LYKYFYAVSN IEVTGRCKCN LHANLCTFKE
GSLQCECEHN TTGQDCGKCK KNFRSRSWRA GSYLPLPNGS PNACAAPGSA YGTYEQPQRV
PTAKTTTAKT TTTPAPTTTT STTSTPLPAT TTQPASTIRP ASEPVRETQK KTDYTSLSAA
APLQVGSPPA KAGPGAEAVE RPPNTAALGP KPKPPDTPEN IRAAPKSKAG RTAGKRHGKK
PASSKSSKLI RLKPDSGPVA PIETYKDCEC YGHSNRCSYI DFLNVVTCVS CKHNTRGQHC
QHCRLGFYRN SSAELDDENV CIECNCNQIG SMHDRCNETG YCECKEGATG PKCDDCLPNY
YWRQGCFPNV CDDELLLCQN GGTCYQNQRC ICPVGFKGVL CQQSRCEADK KDCDGAPSAH
GSLSTVLLGV LALHLRGWVD L
//
