ID A0A2I0M4R1_COLLI Unreviewed; 359 AA.
AC A0A2I0M4R1;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=Interleukin 2 receptor, gamma {ECO:0000313|EMBL:PKK24669.1};
GN Name=IL2RG {ECO:0000313|EMBL:PKK24669.1};
GN ORFNames=A306_00009269 {ECO:0000313|EMBL:PKK24669.1};
OS Columba livia (Rock dove).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Columbiformes; Columbidae; Columba.
OX NCBI_TaxID=8932 {ECO:0000313|EMBL:PKK24669.1, ECO:0000313|Proteomes:UP000053872};
RN [1] {ECO:0000313|EMBL:PKK24669.1, ECO:0000313|Proteomes:UP000053872}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC TISSUE=Blood {ECO:0000313|EMBL:PKK24669.1};
RX PubMed=23371554; DOI=10.1126/science.1230422;
RA Shapiro M.D., Kronenberg Z., Li C., Domyan E.T., Pan H., Campbell M.,
RA Tan H., Huff C.D., Hu H., Vickrey A.I., Nielsen S.C., Stringham S.A.,
RA Hu H., Willerslev E., Gilbert M.T., Yandell M., Zhang G., Wang J.;
RT "Genomic diversity and evolution of the head crest in the rock pigeon.";
RL Science 339:1063-1067(2013).
CC -!- SIMILARITY: Belongs to the type I cytokine receptor family. Type 5
CC subfamily. {ECO:0000256|ARBA:ARBA00008159}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PKK24669.1}.
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DR EMBL; AKCR02000041; PKK24669.1; -; Genomic_DNA.
DR RefSeq; XP_005500525.1; XM_005500468.1.
DR AlphaFoldDB; A0A2I0M4R1; -.
DR STRING; 8932.A0A2I0M4R1; -.
DR GeneID; 102094834; -.
DR KEGG; clv:102094834; -.
DR CTD; 3561; -.
DR InParanoid; A0A2I0M4R1; -.
DR OrthoDB; 5174285at2759; -.
DR Proteomes; UP000053872; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004896; F:cytokine receptor activity; IEA:InterPro.
DR CDD; cd00063; FN3; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 2.
DR InterPro; IPR048648; CRLF2-like_D2.
DR InterPro; IPR048651; CRLF2_D1.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR003531; Hempt_rcpt_S_F1_CS.
DR InterPro; IPR013783; Ig-like_fold.
DR PANTHER; PTHR23037; CYTOKINE RECEPTOR; 1.
DR PANTHER; PTHR23037:SF41; CYTOKINE RECEPTOR-LIKE FACTOR 2-RELATED; 1.
DR Pfam; PF21605; CRLF2-like_D2; 1.
DR Pfam; PF21604; CRLF2_D1; 1.
DR SMART; SM00060; FN3; 1.
DR SUPFAM; SSF49265; Fibronectin type III; 2.
DR PROSITE; PS50853; FN3; 1.
DR PROSITE; PS01355; HEMATOPO_REC_S_F1; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius}; Receptor {ECO:0000313|EMBL:PKK24669.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000053872};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..28
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 29..359
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5014177804"
FT TRANSMEM 237..261
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 131..229
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT REGION 340..359
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 359 AA; 40906 MW; 0BE663126F90AFE2 CRC64;
MAHPAMAVPS AFLVPVLLLL CGLGHCFAAA HSRPGVECVL FNEEYMTCTW GSRETLTANY
SLFYWYENRS PVVECKHYLQ DQGISIGCYF NQSEITQFQT FRVLVNASLG GRTLDIPSKP
MQLQDLVKPA APVNLTIRNM SSNQLQLTWT SPYPKAQCLE HAVKYKSNKD TSWTEHQVKG
DVFSFPSVDY EKYYTFYVRS KINSYCGSTQ LWSEWSVPVV WGSNSTSKGS VEEQLHWFWI
HTVLIPIASC LLLLVLLILL VRMERVWVIL MPRIPNPSKN FENLFITHNG NFQEWAGVPK
DVVESFKPNY SENICHVCEL PPKETYEPLW ESSNHPPVTI STSSVPSEHS PYKNSYTGV
//
