ID   A0A2I0M589_COLLI        Unreviewed;       437 AA.
AC   A0A2I0M589;
DT   28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT   28-FEB-2018, sequence version 1.
DT   22-FEB-2023, entry version 7.
DE   SubName: Full=DEP domain containing 1B, transcript variant X2 {ECO:0000313|EMBL:PKK24849.1};
GN   Name=DEPDC1B {ECO:0000313|EMBL:PKK24849.1};
GN   ORFNames=A306_00010711 {ECO:0000313|EMBL:PKK24849.1};
OS   Columba livia (Rock dove).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Columbiformes; Columbidae; Columba.
OX   NCBI_TaxID=8932 {ECO:0000313|EMBL:PKK24849.1, ECO:0000313|Proteomes:UP000053872};
RN   [1] {ECO:0000313|EMBL:PKK24849.1, ECO:0000313|Proteomes:UP000053872}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   TISSUE=Blood {ECO:0000313|EMBL:PKK24849.1};
RX   PubMed=23371554; DOI=10.1126/science.1230422;
RA   Shapiro M.D., Kronenberg Z., Li C., Domyan E.T., Pan H., Campbell M.,
RA   Tan H., Huff C.D., Hu H., Vickrey A.I., Nielsen S.C., Stringham S.A.,
RA   Hu H., Willerslev E., Gilbert M.T., Yandell M., Zhang G., Wang J.;
RT   "Genomic diversity and evolution of the head crest in the rock pigeon.";
RL   Science 339:1063-1067(2013).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PKK24849.1}.
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DR   EMBL; AKCR02000038; PKK24849.1; -; Genomic_DNA.
DR   RefSeq; XP_013227448.1; XM_013371994.1.
DR   Proteomes; UP000053872; Unassembled WGS sequence.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   CDD; cd04405; RhoGAP_BRCC3-like; 1.
DR   Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR000591; DEP_dom.
DR   InterPro; IPR008936; Rho_GTPase_activation_prot.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR16206; DEP DOMAIN-CONTAINING; 1.
DR   PANTHER; PTHR16206:SF11; DEP DOMAIN-CONTAINING PROTEIN 1B; 1.
DR   Pfam; PF00610; DEP; 1.
DR   SMART; SM00049; DEP; 1.
DR   SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000053872}.
FT   DOMAIN          1..81
FT                   /note="DEP"
FT                   /evidence="ECO:0000259|SMART:SM00049"
SQ   SEQUENCE   437 AA;  50748 MW;  4DC34CDDA94890DF CRC64;
     MPLRKHRCRF KSYERCFKAS EAVDCLHELL GSNQNFGPEV TRNQTVKLLK KFLKNHVIED
     IKGRWGKEDF QDDGHLYRFP PSSPLKPYPK KPSCGREVIK FPDWNEPKAG TSQEHIPVKS
     VTMNSEMWYK RHSIAIGETP ACKLVFRREL TQTNIEEIWK SMTLSQLQKV LGLDSLDEVL
     DTKLVNSKHI VQNAYNVNKQ GIVTLEDKSK ELPHWILSAM KCLANWPSCS DLKQPTYSGF
     ERDVFKTIVD YFGQMKEPLL TFHFFDVFVS VLGLLQKHSK AIEALQISCL LLPXXXXXXX
     XRMMARISCN KDLPPLSESV RTRTLMVQAF SRCILCSKDE MDLDELLAAK LVSFLMDNYQ
     EILSVPSTLK SSIEEHVVRL QRVQFQKSYP EVYRVRFPTP ETEAVLFPEK NKQKPPILMW
     ALKKPFQPFH RTRSFRM
//