ID A0A2I0M6A8_COLLI Unreviewed; 359 AA.
AC A0A2I0M6A8;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 24-JAN-2024, entry version 14.
DE SubName: Full=N-acetylneuraminic acid synthase {ECO:0000313|EMBL:PKK25211.1};
GN Name=NANS {ECO:0000313|EMBL:PKK25211.1};
GN ORFNames=A306_00009553 {ECO:0000313|EMBL:PKK25211.1};
OS Columba livia (Rock dove).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Columbiformes; Columbidae; Columba.
OX NCBI_TaxID=8932 {ECO:0000313|EMBL:PKK25211.1, ECO:0000313|Proteomes:UP000053872};
RN [1] {ECO:0000313|EMBL:PKK25211.1, ECO:0000313|Proteomes:UP000053872}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC TISSUE=Blood {ECO:0000313|EMBL:PKK25211.1};
RX PubMed=23371554; DOI=10.1126/science.1230422;
RA Shapiro M.D., Kronenberg Z., Li C., Domyan E.T., Pan H., Campbell M.,
RA Tan H., Huff C.D., Hu H., Vickrey A.I., Nielsen S.C., Stringham S.A.,
RA Hu H., Willerslev E., Gilbert M.T., Yandell M., Zhang G., Wang J.;
RT "Genomic diversity and evolution of the head crest in the rock pigeon.";
RL Science 339:1063-1067(2013).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PKK25211.1}.
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DR EMBL; AKCR02000034; PKK25211.1; -; Genomic_DNA.
DR RefSeq; XP_005504652.1; XM_005504595.1.
DR AlphaFoldDB; A0A2I0M6A8; -.
DR STRING; 8932.A0A2I0M6A8; -.
DR GeneID; 102088004; -.
DR KEGG; clv:102088004; -.
DR CTD; 54187; -.
DR InParanoid; A0A2I0M6A8; -.
DR OrthoDB; 3716025at2759; -.
DR Proteomes; UP000053872; Unassembled WGS sequence.
DR GO; GO:0016051; P:carbohydrate biosynthetic process; IEA:InterPro.
DR CDD; cd11615; SAF_NeuB_like; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR Gene3D; 3.90.1210.10; Antifreeze-like/N-acetylneuraminic acid synthase C-terminal domain; 1.
DR InterPro; IPR006190; AFP_Neu5c_C.
DR InterPro; IPR036732; AFP_Neu5c_C_sf.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR013132; Neu5Ac_N.
DR InterPro; IPR013974; SAF.
DR PANTHER; PTHR42966; N-ACETYLNEURAMINATE SYNTHASE; 1.
DR PANTHER; PTHR42966:SF1; SIALIC ACID SYNTHASE; 1.
DR Pfam; PF03102; NeuB; 1.
DR Pfam; PF08666; SAF; 1.
DR SMART; SM00858; SAF; 1.
DR SUPFAM; SSF51269; AFP III-like domain; 1.
DR SUPFAM; SSF51569; Aldolase; 1.
DR PROSITE; PS50844; AFP_LIKE; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000053872}.
FT DOMAIN 294..353
FT /note="AFP-like"
FT /evidence="ECO:0000259|PROSITE:PS50844"
SQ SEQUENCE 359 AA; 40169 MW; 91D303784AD2EEB4 CRC64;
MSREFELCPG RRIGGEQPCF IIAEIGQNHQ GDLDIAKRMI RMAKDCGADC AKFQKSELEY
KFNKKALERP YTSKHSWGKT YGEHKRHLEF SHDEYRELRK YAEEIGIFFT ASGMDEMAVE
FLHELDVPFF KVGSGDTNNF PYLEKTAKKG RPMVISSGMQ SMDTMHRVYQ IVKAINPNFC
FLQCTSAYPL QPEDVNLRVI SAYQSAFPDI PIGYSGHETG IAISVAAVAM GAKVVERHVT
LNKTWKGSDH QASLEPNELA ELVKAIRTVE KAMGSPVKQL LPCEMACSEK LGKSVVAKVT
IPEGAVLTLD MLTVKVGEPK GFPPEAIYDL VGQKVKKNIE EDETITEEAV ENHVKKVKC
//
