ID A0A2I0M8A0_COLLI Unreviewed; 193 AA.
AC A0A2I0M8A0;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE SubName: Full=Myosin regulatory light chain 2A, cardiac muscle isoform {ECO:0000313|EMBL:PKK25903.1};
GN ORFNames=A306_00005366 {ECO:0000313|EMBL:PKK25903.1};
OS Columba livia (Rock dove).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Columbiformes; Columbidae; Columba.
OX NCBI_TaxID=8932 {ECO:0000313|EMBL:PKK25903.1, ECO:0000313|Proteomes:UP000053872};
RN [1] {ECO:0000313|EMBL:PKK25903.1, ECO:0000313|Proteomes:UP000053872}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC TISSUE=Blood {ECO:0000313|EMBL:PKK25903.1};
RX PubMed=23371554; DOI=10.1126/science.1230422;
RA Shapiro M.D., Kronenberg Z., Li C., Domyan E.T., Pan H., Campbell M.,
RA Tan H., Huff C.D., Hu H., Vickrey A.I., Nielsen S.C., Stringham S.A.,
RA Hu H., Willerslev E., Gilbert M.T., Yandell M., Zhang G., Wang J.;
RT "Genomic diversity and evolution of the head crest in the rock pigeon.";
RL Science 339:1063-1067(2013).
CC -!- SUBUNIT: Myosin is a hexamer of 2 heavy chains and 4 light chains.
CC {ECO:0000256|ARBA:ARBA00011445}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PKK25903.1}.
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DR EMBL; AKCR02000030; PKK25903.1; -; Genomic_DNA.
DR RefSeq; XP_005498282.2; XM_005498225.2.
DR AlphaFoldDB; A0A2I0M8A0; -.
DR STRING; 8932.A0A2I0M8A0; -.
DR GeneID; 102098030; -.
DR KEGG; clv:102098030; -.
DR InParanoid; A0A2I0M8A0; -.
DR OrthoDB; 312751at2759; -.
DR Proteomes; UP000053872; Unassembled WGS sequence.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR CDD; cd00051; EFh; 1.
DR Gene3D; 1.10.238.10; EF-hand; 2.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR InterPro; IPR002048; EF_hand_dom.
DR PANTHER; PTHR23049; MYOSIN REGULATORY LIGHT CHAIN 2; 1.
DR PANTHER; PTHR23049:SF9; MYOSIN REGULATORY LIGHT CHAIN 2, VENTRICULAR_CARDIAC MUSCLE ISOFORM; 1.
DR Pfam; PF13405; EF-hand_6; 1.
DR SMART; SM00054; EFh; 2.
DR SUPFAM; SSF47473; EF-hand; 1.
DR PROSITE; PS00018; EF_HAND_1; 1.
DR PROSITE; PS50222; EF_HAND_2; 2.
PE 4: Predicted;
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000053872};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 52..87
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 157..192
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
SQ SEQUENCE 193 AA; 21972 MW; 65D9B9F3C5E72E31 CRC64;
MYLLFQPGGR EGLPPRRLSQ QHQQLCKAMA PKKAKKRIEG ANSNVFSMFE QAQIQEFKEA
FTIMDQNRDG FIDKADLRDT FAALGRLNVK NEEIDEMIKE APGPINFTVF LTMFGEKLKG
ADPEETILNA FKVFDPEGKG LKSAYIKEML MTQGERFSQE EIDQMFAAFP PDMSGNLDYK
NLVHVITHGE EKD
//
