ID A0A2I0M9R6_COLLI Unreviewed; 1209 AA.
AC A0A2I0M9R6;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Cell adhesion molecule L1-like {ECO:0000313|EMBL:PKK26409.1};
GN Name=CHL1 {ECO:0000313|EMBL:PKK26409.1};
GN ORFNames=A306_00009060 {ECO:0000313|EMBL:PKK26409.1};
OS Columba livia (Rock dove).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Columbiformes; Columbidae; Columba.
OX NCBI_TaxID=8932 {ECO:0000313|EMBL:PKK26409.1, ECO:0000313|Proteomes:UP000053872};
RN [1] {ECO:0000313|EMBL:PKK26409.1, ECO:0000313|Proteomes:UP000053872}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC TISSUE=Blood {ECO:0000313|EMBL:PKK26409.1};
RX PubMed=23371554; DOI=10.1126/science.1230422;
RA Shapiro M.D., Kronenberg Z., Li C., Domyan E.T., Pan H., Campbell M.,
RA Tan H., Huff C.D., Hu H., Vickrey A.I., Nielsen S.C., Stringham S.A.,
RA Hu H., Willerslev E., Gilbert M.T., Yandell M., Zhang G., Wang J.;
RT "Genomic diversity and evolution of the head crest in the rock pigeon.";
RL Science 339:1063-1067(2013).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-
CC pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
CC -!- SIMILARITY: Belongs to the immunoglobulin superfamily.
CC L1/neurofascin/NgCAM family. {ECO:0000256|ARBA:ARBA00008588}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PKK26409.1}.
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DR EMBL; AKCR02000026; PKK26409.1; -; Genomic_DNA.
DR RefSeq; XP_005508843.1; XM_005508786.2.
DR AlphaFoldDB; A0A2I0M9R6; -.
DR STRING; 8932.A0A2I0M9R6; -.
DR GeneID; 102087472; -.
DR KEGG; clv:102087472; -.
DR CTD; 10752; -.
DR InParanoid; A0A2I0M9R6; -.
DR OrthoDB; 2912783at2759; -.
DR Proteomes; UP000053872; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR GO; GO:0007399; P:nervous system development; IEA:UniProtKB-KW.
DR CDD; cd00063; FN3; 4.
DR CDD; cd05845; IgI_2_L1-CAM_like; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 10.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR013098; Ig_I-set.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR InterPro; IPR026966; Neurofascin/L1/NrCAM_C.
DR PANTHER; PTHR44170:SF51; NEURAL CELL ADHESION MOLECULE L1-LIKE PROTEIN ISOFORM X1; 1.
DR PANTHER; PTHR44170; PROTEIN SIDEKICK; 1.
DR Pfam; PF13882; Bravo_FIGEY; 1.
DR Pfam; PF00041; fn3; 4.
DR Pfam; PF07679; I-set; 1.
DR Pfam; PF13927; Ig_3; 4.
DR SMART; SM00060; FN3; 4.
DR SMART; SM00409; IG; 6.
DR SMART; SM00408; IGc2; 5.
DR SUPFAM; SSF49265; Fibronectin type III; 2.
DR SUPFAM; SSF48726; Immunoglobulin; 6.
DR PROSITE; PS50853; FN3; 4.
DR PROSITE; PS50835; IG_LIKE; 6.
PE 3: Inferred from homology;
KW Cell adhesion {ECO:0000256|ARBA:ARBA00022889};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Immunoglobulin domain {ECO:0000256|ARBA:ARBA00023319};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000053872};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}; Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..24
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 25..1209
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5014183557"
FT TRANSMEM 1083..1104
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 35..125
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 129..222
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 236..327
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 332..417
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 423..510
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 515..607
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 614..709
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 714..807
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 812..914
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 918..1015
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT REGION 694..716
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1189..1209
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1191..1209
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1209 AA; 134244 MW; FBCB9842A062F712 CRC64;
MEALLSTKGI AICLFFSVLN LTAAIEIPLS VVQLPTITEQ PRTQVAYPFD EDFTIKCEAR
GNPHPTFNWT KDGKPFDLLS DPRIVASNNS GTFVLQNRGI ITSFQGKYRC FASNMLGTTM
SEEIELIVPS VPKFPKEKIE PLDVEHGDSV ILHCNPPKGI PPLHIYWMNI DLQHIPQDER
VSMSLKGDLY FANVEENDSR SDYCCFAAFP TLRTIVQKMP MTLKVSRSNF IKERKPKLLI
PPESAGSSSS VTVIKGGVLL LECIAEGLPT PHLSWVKLTG NLPRDEPETE NFGKILKIEQ
ATAADEGTYQ CTASNPMGRA KHEFHVHVEE PPQWIKEPEG GVYSIGTNLV LLCEAIGNPE
PTIQWKLNGA PIDSRTFRGR ISAREISLTN LQLQDSAVYQ CEASNKHGTI LATANVNVLN
IAPLILTSDG ENYATVVGYS AFLHCEIFAS PAADIRWTKD ESIEPLLTSR YELNKNGTLE
IKETKKEDTG SYACWAANSV GKRAITANLD IRDATKLVVT PKNPRVLKSH SVLLKCQSEY
DSHLKHSFRL SWRKDGDELP VNSTEDGRII LDKDTLFISS VTLKDQGVYT CVARTSLDSV
TAESQLVVLD VPDPPEDLQL SENQNRSVRL SWKAGASHNS PINELIIEFE EDRWEPGRWQ
ELTRAPGNDT TVLLSLAPYM NYQFRVVSVN AVGRSQPSKP SLRYATPPAA PDKNPENIRV
EASEPDEMVM KWEPLKPMER NGPGLEYKVS WRQRGVEADW NEETVKKHSL TLRNTPTFVP
YEIKVQAVNN LGSGPEPNVT IGYSGEDIPD AAPSDVSVDI VNSTLVKVFW FGIPKDRVRG
HLRGYKVNWW KTKSMLDGKR HHPEKQFLTF VGDRNYGMIP GLEAFSEFRL TVLAYNSKGD
GPESSPIVFE TPEGVPEQPR FLRILNFDKD SVTLSWGLPK KANGHLTGYI LQYQMINETH
EIGPLNDVSV TNRSTLSWRL SGLSSSTKYK FYVKACTVKG CGKPVTEEGL TMAQGSKGIG
KISEAVNPTQ KFHPIEALEP GTEYTVRLVT KNWVDNNSIF EDVIETRGRA YAGIYDGIST
QGWFIGLMCA IALLTLLLLT ICFVRRNKGG KYSVKEKEDL HPDPEAQSIK DEIFGEYSDS
DEKPLKGSLQ SINGDIKATE SADSLVDYGE GEHGMFNEDG SFIGAYSGSK EKGSVESTGS
STATFPLHA
//
