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Database: UniProt
Entry: A0A2I0MAR0_COLLI
LinkDB: A0A2I0MAR0_COLLI
Original site: A0A2I0MAR0_COLLI 
ID   A0A2I0MAR0_COLLI        Unreviewed;      2943 AA.
AC   A0A2I0MAR0;
DT   28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT   28-FEB-2018, sequence version 1.
DT   07-OCT-2020, entry version 9.
DE   SubName: Full=Centromere protein F, 350/400kDa {ECO:0000313|EMBL:PKK26764.1};
GN   Name=CENPF {ECO:0000313|EMBL:PKK26764.1};
GN   ORFNames=A306_00008694 {ECO:0000313|EMBL:PKK26764.1};
OS   Columba livia (Rock dove).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Columbiformes; Columbidae; Columba.
OX   NCBI_TaxID=8932 {ECO:0000313|EMBL:PKK26764.1, ECO:0000313|Proteomes:UP000053872};
RN   [1] {ECO:0000313|EMBL:PKK26764.1, ECO:0000313|Proteomes:UP000053872}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   TISSUE=Blood {ECO:0000313|EMBL:PKK26764.1};
RX   PubMed=23371554; DOI=10.1126/science.1230422;
RA   Shapiro M.D., Kronenberg Z., Li C., Domyan E.T., Pan H., Campbell M.,
RA   Tan H., Huff C.D., Hu H., Vickrey A.I., Nielsen S.C., Stringham S.A.,
RA   Hu H., Willerslev E., Gilbert M.T., Yandell M., Zhang G., Wang J.;
RT   "Genomic diversity and evolution of the head crest in the rock pigeon.";
RL   Science 339:1063-1067(2013).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PKK26764.1}.
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DR   EMBL; AKCR02000024; PKK26764.1; -; Genomic_DNA.
DR   Proteomes; UP000053872; Unassembled WGS sequence.
DR   GO; GO:0000775; C:chromosome, centromeric region; IEA:InterPro.
DR   GO; GO:0070840; F:dynein complex binding; IEA:InterPro.
DR   GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR   GO; GO:0042803; F:protein homodimerization activity; IEA:InterPro.
DR   GO; GO:0008134; F:transcription factor binding; IEA:InterPro.
DR   InterPro; IPR043513; Cenp-F.
DR   InterPro; IPR018302; CenpF/LEK1_Rb-prot-bd.
DR   InterPro; IPR019513; Centromere_CenpF_leu-rich_rpt.
DR   InterPro; IPR018463; Centromere_CenpF_N.
DR   PANTHER; PTHR18874; PTHR18874; 1.
DR   Pfam; PF10490; CENP-F_C_Rb_bdg; 1.
DR   Pfam; PF10473; CENP-F_leu_zip; 2.
DR   Pfam; PF10481; CENP-F_N; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Reference proteome {ECO:0000313|Proteomes:UP000053872}.
FT   DOMAIN          1..296
FT                   /note="CENP-F_N"
FT                   /evidence="ECO:0000259|Pfam:PF10481"
FT   DOMAIN          1923..2038
FT                   /note="CENP-F_leu_zip"
FT                   /evidence="ECO:0000259|Pfam:PF10473"
FT   DOMAIN          2136..2273
FT                   /note="CENP-F_leu_zip"
FT                   /evidence="ECO:0000259|Pfam:PF10473"
FT   DOMAIN          2792..2835
FT                   /note="CENP-F_C_Rb_bdg"
FT                   /evidence="ECO:0000259|Pfam:PF10490"
FT   REGION          211..238
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1238..1265
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1726..1747
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          2721..2783
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          2854..2943
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          13..85
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          97..131
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          162..189
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          270..435
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          471..505
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          513..605
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          620..640
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          673..703
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          708..735
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          833..853
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          890..934
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          956..993
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1009..1069
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1075..1095
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1157..1184
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1192..1233
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1279..1299
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1584..1622
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1627..1649
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1923..1950
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1972..2090
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2098..2118
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2147..2230
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2242..2276
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2298..2377
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2398..2485
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2493..2545
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2561..2609
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2617..2647
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2693..2713
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        1238..1259
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1733..1747
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        2721..2747
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        2748..2783
FT                   /note="Polyampholyte"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        2863..2912
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   2943 AA;  339242 MW;  F74F5A88ED6D0129 CRC64;
     MSWAVEEWKE GLSPRVLQKI HELESQVDKL KKERQQRQFQ LESLEAALQK QKQKVENEKN
     EAATLKRENQ SLMELCDSLE KAKQKISHDL QVKESQVNIQ SGQLNSSKKD IERLEQELKR
     YKCELERSQQ ASIVGDLSFS GTPQKSFTGP LTPVQSHNDA KFEELEEKYK KEVQERKKLE
     LELRTIQVKK INHPQLQSSL SHREIARHQA SSSVFSWQQE KTPSRNQETP ARGSSTMSFF
     PWEKETNSSI ISEKNELNNS FAENCNSSLL IQLRAQNQEL NSTVKDLEQQ LEAQEKVTKS
     HINKHQEAEV QLDRMKLELT EKDKVLNKTR DKLTQMRTQL DQATTQVQMM EQKVKRLSEE
     LNCQRQNAES ARQSLEQKIK TKEKEYQQEL SCQQRALQTL DQQCNQIRNK LNQELQQAKN
     DFNALQAEFD KVMAVKQRLE HDTSNLTQQL CRAEQTLSAA RAKEADLTRS FEEVKQQKNL
     LDCQLEKKLQ EIHQLEEELS TIKQSLKQSQ DFAVEMKNKN AFQEAELKLL EEKFKKQESS
     VLVENLKRAL ADMEKQQDST QDLLKEKENQ IKEQNCKINK MEEESEALQI LLGFKQRECE
     ELQKEATAFS QWKNENDHLI NELKSEKEGM LTHINDLEIS LRSQEIKNHE CSEKLRMMET
     ESDRKSTEIG ELKDMLECKC TELEEQKKAS DELQRKAEFS DKKYCKEIEN MSCKILQLTN
     QVSELEEKLQ LSASEGLQRE QCYHDLLGEY EKICCLVKAK DTSEMMEDGE VNLQSDQEKT
     VLGNAQLAAN NSIAEDQGCA RALLEVGKPK DLAILQDQIS SLELSLVAQK QLNSNQQQQY
     EDLLQIKGET EERLLNVEQM HETFVTETKQ HISDLQADIS ARQKLVEKTL AILEEKDMQL
     QTLNERLENQ QAELEDWKIN NKLLEDSLRQ LRLMSGTWDS EKKDMSSMIC SYSKKIEELT
     AENATLRDLS RALEQEQITL LEANKNISDH LKEKGEIISE MSGKHKEERQ RIESRTEEIK
     AELKVLQEKY KSVEEENANL MSILREQAIE SEEKNAKLEQ EKLVFSENRD ILCKLIASEE
     IKKDLVQELQ QLHSEFSSVQ HVPSVELQEM LNVRATQNTM QEKCDIVFQD KEQLGKGLET
     KSEPLTCDVY CQQRLHSEQL RKSMEEKETE LNKYQVKLEL LQMDFEDREL SLENCKLEVM
     QLETALKGME AELEKSVREK ERLQQELLSV KELKTSDSSL TGLDEDGHSL QYNYESDSQN
     RGKRGMDESY SSVLLASSLQ VAINHLSELE KMCERFQSEN IVIATGFKGS KTDDITSINE
     VAEGEENKTN ADKKLKVDKA IFPDELMDQS DNSNIRMHFD NKEMSFKRKE CSTGHSPDYE
     DLKLSSKEVI THFAEIREKL LSFQNEHMKL YEQHCSMSSK ISELQSCIEI LKAENSALST
     SLSNVHIASL RVPLSSSQND TFSKLDETKS TVSSSEHFES PCFIQVSEVV DSCNSGMYKW
     AEEMNQPDSS AEIIPGGATE VLVENCHNGC KLDSVREPGS ISPRKSSPES RTEELQMLCQ
     IYEKAIKVLQ DRFHIQENMN TEEIQELKKV ILSEREEIDN LKKQHLSDKE EWQQKLNKVT
     MEMECKLAAE RKQTENLSLE LEAARLQLQV LDLSSHSLLC TDIENNTEQE SNSPYQLRVP
     IANSALKSNN PKLISVEKMA VGDTSVCENV TETSEARLME DDTGKISGEH ECRNTSGEIT
     SPSDPASALS FSNSDMILSA GDFFGNQVTP ETLQEEAKQQ TAENVKVIYE TEESRKHIDL
     PMKTEQLNSE LNFQNAQFTP KSSASAEPEQ TTVVVKEENC DIKEKTQSVS VNKQELSLGV
     VSWEKEPEKA KSELEIHKVS LSNAADTLDD VEMMNRDCHE QFLAAENEQI RPKSEPVVME
     NCALSTENYI EMLQAKYQQL EREREVNLKT IAGLQEHLVS VTAERNHIGQ ELSVLSENKK
     ELDQKYQKLQ EKLKELESTN VDSTEFIRRL ESEVRTQMNL FEAAKSDVNQ LSNEKDQLLQ
     NLQSLEQDAM SFALEKEKLQ NKATDLNEEK ELLVRELEMM QSKLRSSEME NSRLSRSLEG
     LLMEKGELAA RLSSAQKEVD QMRYGIEKLK VKIESDEKKK CHVAEKLKES ERKADSLLDK
     IERLERELEM SEKNLEDVIV QSETAKAEAE TLTMEKEEMA EKLKCFNLQI DVLTSQKESL
     AKDLKEKQER VCELESSHLT TAKLLEEKEE EKMQIKDEFE NTVVLLKSEL KDVRKKFEFS
     CKEEADARAK EQVLINQVAC LEQDKTMLLQ ECQEIKNENK MLDQMKAVLI QELTDCKQKL
     DEKVQENGAL QKQVKEAEEL SSEMTHMQQE HECWHQEKKS LQNLISELKL KEQHFSDNET
     IQDILNVLKV SYKDLEKELE SALCEKSTLC EKVNELTESY IELQVKLSDA EQKISKLQEE
     STRERNQLAE EIQLLQEHSE KSKNQLHLTM SEKNELTKSL EMLQKDLHER ESEMKREISE
     YKDRLLQAEK EHEDALTEAN RKNEVEIEAC QDKLNSLEHF IRSQKLEIEH LKSNKEELNN
     SLKEANQTLE ELLKTKADNI NTIVQLKKEN EFAHSKAKLW MKTCKQMEQE KETLQKQLVE
     RDELLKKKNL SADENAITEE IKLKLEELQE STEVKTREAN ENLEKYCSLI VKYYKLEEEN
     EMLKTQVSLL SAQLKQPTSE AVSTPLLNSE NSLTESNQSV KQMRADGDTT KLSSKRQRYE
     DNRNDNEEPR SPVPETLSKK KRKDDICQHL LGQENTDYEP DGLPEVVKKG FSDIPTGKVS
     PYILRRTTLN LRTSPHLACP SEKLPLAAQD VEKCKPDNLG ERSRSTPGGS KPQKVNDEQQ
     SPAVTAQPPL KSTSRSPLCL YKQSTKTGSD NIRESCMMHK AKNSPNEQGL LEQDEQKENC
     KVQ
//
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