ID A0A2I0MBA4_COLLI Unreviewed; 975 AA.
AC A0A2I0MBA4;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 24-JAN-2024, entry version 22.
DE RecName: Full=Polyhomeotic homolog 3 {ECO:0008006|Google:ProtNLM};
GN ORFNames=A306_00007716 {ECO:0000313|EMBL:PKK26957.1};
OS Columba livia (Rock dove).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Columbiformes; Columbidae; Columba.
OX NCBI_TaxID=8932 {ECO:0000313|EMBL:PKK26957.1, ECO:0000313|Proteomes:UP000053872};
RN [1] {ECO:0000313|EMBL:PKK26957.1, ECO:0000313|Proteomes:UP000053872}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC TISSUE=Blood {ECO:0000313|EMBL:PKK26957.1};
RX PubMed=23371554; DOI=10.1126/science.1230422;
RA Shapiro M.D., Kronenberg Z., Li C., Domyan E.T., Pan H., Campbell M.,
RA Tan H., Huff C.D., Hu H., Vickrey A.I., Nielsen S.C., Stringham S.A.,
RA Hu H., Willerslev E., Gilbert M.T., Yandell M., Zhang G., Wang J.;
RT "Genomic diversity and evolution of the head crest in the rock pigeon.";
RL Science 339:1063-1067(2013).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PKK26957.1}.
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DR EMBL; AKCR02000022; PKK26957.1; -; Genomic_DNA.
DR RefSeq; XP_013225713.1; XM_013370259.1.
DR AlphaFoldDB; A0A2I0MBA4; -.
DR STRING; 8932.A0A2I0MBA4; -.
DR GeneID; 102092245; -.
DR KEGG; clv:102092245; -.
DR CTD; 80012; -.
DR InParanoid; A0A2I0MBA4; -.
DR OrthoDB; 5399754at2759; -.
DR Proteomes; UP000053872; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0032991; C:protein-containing complex; IEA:UniProt.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd09577; SAM_Ph1_2_3; 1.
DR Gene3D; 3.30.60.160; -; 1.
DR Gene3D; 1.10.150.50; Transcription Factor, Ets-1; 1.
DR InterPro; IPR001660; SAM.
DR InterPro; IPR013761; SAM/pointed_sf.
DR InterPro; IPR012313; Znf_FCS.
DR InterPro; IPR038603; Znf_FCS_sf.
DR PANTHER; PTHR12247; POLYCOMB GROUP PROTEIN; 1.
DR PANTHER; PTHR12247:SF88; POLYHOMEOTIC-LIKE PROTEIN 3; 1.
DR Pfam; PF00536; SAM_1; 1.
DR Pfam; PF21319; zf-FCS_1; 1.
DR SMART; SM00454; SAM; 1.
DR SUPFAM; SSF47769; SAM/Pointed domain; 1.
DR PROSITE; PS50105; SAM_DOMAIN; 1.
DR PROSITE; PS51024; ZF_FCS; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000053872};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00367}.
FT DOMAIN 762..796
FT /note="FCS-type"
FT /evidence="ECO:0000259|PROSITE:PS51024"
FT DOMAIN 911..975
FT /note="SAM"
FT /evidence="ECO:0000259|PROSITE:PS50105"
FT REGION 1..23
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 121..145
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 220..277
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 297..398
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 419..460
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 597..678
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 815..843
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 310..334
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 335..349
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 374..398
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 419..437
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 625..643
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 658..677
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 975 AA; 104740 MW; FDE189C209B82F78 CRC64;
MENEPNTTTC SASTTTITTT STSRTQLPQI SVYSGSDRHA VQVIQQALHR PPSSAAQYLQ
QMYAAQQQHL MLQTAALQQQ HLSSTQFQSL ATVPQASLSG GRQCTSPTGS VTQQSSMSQT
SINLSTSPTP AQIISRSQTS NTTTSSITQQ TMLLGSTSPT LSASQAQMYL RAQMLIFTPA
TTVAAVQSDI PVVSSSSSSS CQSAATQVQN LTLRSQKLGV LSGSQNGPPK SSSQAPSLSL
CKPATSSKGS QPDPSESNRK GESPTPECRS TPVTRTSSIH HLITPASYSP LQPHSLVKHQ
LHSPPPKISH HQLILQQQQQ VQPIALQTPS GQDPPPSQHC LPLPSHGLPP APSGVQSHCS
PIHIHPPPLT LSPTPSQSAQ QSVVVSPPPS HSPSHSPTII IHPQALIQSQ ANSLVPTALQ
AEQAAPQQTT SPVRPIAQPL NLPSHLPLPS SPAVQIGSVD QPSLVSPGQQ IVSSTPHQQY
SALQSTPIPL AAPPQLSASS AQIQQLPLQS VPSLQVQPEI LSQGQVLVQN TLVSEEELPA
AEALVQLPFQ TLPPPQTVAV NLQVQPSVPI ETPVIYQVEN VCEEEMPEES DCVHMARTPT
PPTLSPPAGN GETLNSEDPL SEHGGLPSVT SSVSASVIKS PSDPSHASIP PPPLLLPAAT
TRSNSTSMPN SIPSLENKPP QAIVKPQILT HVIEGFVIQE GLEPFPVSRS SLLVEQPAEK
RLLVEGQIMS VVCVESDLQN TKHADNSSDT EIEDMIAEEG LDEIENDLLK CEFCGKMGYS
NKFLRSKRFC STSCAKRHSL SCTKKFGLFT SDKTSRWNRK SDSQSLGRRG RRPSGPDGAS
RDHFLRQLPI TYPSAEEDMA SHEDAVPAAM TTRLRRQSER ERERELRELR IRKMPESIDL
LPVVQADPSV WTVDEVWAFI HSLPGCQDIA DEFRAQEIDG QALLLLKEDH LMSAMNIKLG
PALKICARIN SLKES
//
