ID A0A2I0MBE9_COLLI Unreviewed; 301 AA.
AC A0A2I0MBE9;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=SRY (Sex determining region Y)-box 2 {ECO:0000313|EMBL:PKK27006.1};
DE Flags: Fragment;
GN Name=SOX2 {ECO:0000313|EMBL:PKK27006.1};
GN ORFNames=A306_00007748 {ECO:0000313|EMBL:PKK27006.1};
OS Columba livia (Rock dove).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Columbiformes; Columbidae; Columba.
OX NCBI_TaxID=8932 {ECO:0000313|EMBL:PKK27006.1, ECO:0000313|Proteomes:UP000053872};
RN [1] {ECO:0000313|EMBL:PKK27006.1, ECO:0000313|Proteomes:UP000053872}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC TISSUE=Blood {ECO:0000313|EMBL:PKK27006.1};
RX PubMed=23371554; DOI=10.1126/science.1230422;
RA Shapiro M.D., Kronenberg Z., Li C., Domyan E.T., Pan H., Campbell M.,
RA Tan H., Huff C.D., Hu H., Vickrey A.I., Nielsen S.C., Stringham S.A.,
RA Hu H., Willerslev E., Gilbert M.T., Yandell M., Zhang G., Wang J.;
RT "Genomic diversity and evolution of the head crest in the rock pigeon.";
RL Science 339:1063-1067(2013).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PKK27006.1}.
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DR EMBL; AKCR02000022; PKK27006.1; -; Genomic_DNA.
DR RefSeq; XP_005506642.1; XM_005506585.1.
DR AlphaFoldDB; A0A2I0MBE9; -.
DR SMR; A0A2I0MBE9; -.
DR STRING; 8932.A0A2I0MBE9; -.
DR GeneID; 102086348; -.
DR KEGG; clv:102086348; -.
DR CTD; 6657; -.
DR InParanoid; A0A2I0MBE9; -.
DR OrthoDB; 2902801at2759; -.
DR Proteomes; UP000053872; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-UniRule.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd01388; HMG-box_SoxB; 1.
DR Gene3D; 1.10.30.10; High mobility group box domain; 1.
DR InterPro; IPR009071; HMG_box_dom.
DR InterPro; IPR036910; HMG_box_dom_sf.
DR InterPro; IPR022097; SOX_fam.
DR PANTHER; PTHR10270; SOX TRANSCRIPTION FACTOR; 1.
DR PANTHER; PTHR10270:SF231; TRANSCRIPTION FACTOR SOX-2; 1.
DR Pfam; PF00505; HMG_box; 1.
DR Pfam; PF12336; SOXp; 1.
DR SMART; SM00398; HMG; 1.
DR SUPFAM; SSF47095; HMG-box; 1.
DR PROSITE; PS50118; HMG_BOX_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00267};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00267}; Reference proteome {ECO:0000313|Proteomes:UP000053872}.
FT DOMAIN 39..107
FT /note="HMG box"
FT /evidence="ECO:0000259|PROSITE:PS50118"
FT DNA_BIND 39..107
FT /note="HMG box"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00267"
FT REGION 1..42
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 236..264
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 279..301
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 10..38
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 236..262
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 301
FT /evidence="ECO:0000313|EMBL:PKK27006.1"
SQ SEQUENCE 301 AA; 33120 MW; C3797C7089CF4B54 CRC64;
MYNMMETELK PPAPQQTSGG GTGNSNSAAN NQKNSPDRVK RPMNAFMVWS RGQRRKMAQE
NPKMHNSEIS KRLGAEWKLL SEAEKRPFID EAKRLRALHM KEHPDYKYRP RRKTKTLMKK
DKYTLPGGLL APGTNTMTTG VGVGATLGAG VNQRMDSYAH MNGWTNGGYG MMQEQLGYPQ
HPGLNAHNAA QMQPMHRYDV SALQYNSMTS SQTYMNGSPT YSMSYSQQGT PGMALGSMGS
VVKTESSSSP PVVTSSSHSR APCQAGDLRD MISMYLPGAE VPEPAAPSRL HMSQHYQSAP
V
//
