ID A0A2I0MDJ5_COLLI Unreviewed; 281 AA.
AC A0A2I0MDJ5;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 24-JAN-2024, entry version 17.
DE RecName: Full=Acidic leucine-rich nuclear phosphoprotein 32 family member {ECO:0000256|RuleBase:RU369103};
GN Name=ANP32A {ECO:0000313|EMBL:PKK27751.1};
GN ORFNames=A306_00005656 {ECO:0000313|EMBL:PKK27751.1};
OS Columba livia (Rock dove).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Columbiformes; Columbidae; Columba.
OX NCBI_TaxID=8932 {ECO:0000313|EMBL:PKK27751.1, ECO:0000313|Proteomes:UP000053872};
RN [1] {ECO:0000313|EMBL:PKK27751.1, ECO:0000313|Proteomes:UP000053872}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC TISSUE=Blood {ECO:0000313|EMBL:PKK27751.1};
RX PubMed=23371554; DOI=10.1126/science.1230422;
RA Shapiro M.D., Kronenberg Z., Li C., Domyan E.T., Pan H., Campbell M.,
RA Tan H., Huff C.D., Hu H., Vickrey A.I., Nielsen S.C., Stringham S.A.,
RA Hu H., Willerslev E., Gilbert M.T., Yandell M., Zhang G., Wang J.;
RT "Genomic diversity and evolution of the head crest in the rock pigeon.";
RL Science 339:1063-1067(2013).
CC -!- FUNCTION: Multifunctional protein that is involved in the regulation of
CC many processes. {ECO:0000256|RuleBase:RU369103}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|RuleBase:RU369103}.
CC -!- SIMILARITY: Belongs to the ANP32 family.
CC {ECO:0000256|ARBA:ARBA00025777, ECO:0000256|RuleBase:RU369103}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PKK27751.1}.
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DR EMBL; AKCR02000019; PKK27751.1; -; Genomic_DNA.
DR RefSeq; XP_013225415.1; XM_013369961.1.
DR AlphaFoldDB; A0A2I0MDJ5; -.
DR STRING; 8932.A0A2I0MDJ5; -.
DR GeneID; 102093694; -.
DR KEGG; clv:102093694; -.
DR CTD; 8125; -.
DR InParanoid; A0A2I0MDJ5; -.
DR OrthoDB; 1386993at2759; -.
DR Proteomes; UP000053872; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR InterPro; IPR045081; AN32.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR003603; U2A'_phosphoprotein32A_C.
DR PANTHER; PTHR11375; ACIDIC LEUCINE-RICH NUCLEAR PHOSPHOPROTEIN 32; 1.
DR PANTHER; PTHR11375:SF1; ACIDIC LEUCINE-RICH NUCLEAR PHOSPHOPROTEIN 32 FAMILY MEMBER A; 1.
DR Pfam; PF14580; LRR_9; 1.
DR SMART; SM00446; LRRcap; 1.
DR SUPFAM; SSF52058; L domain-like; 1.
DR PROSITE; PS51450; LRR; 1.
PE 3: Inferred from homology;
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614,
KW ECO:0000256|RuleBase:RU369103}; Nucleus {ECO:0000256|RuleBase:RU369103};
KW Reference proteome {ECO:0000313|Proteomes:UP000053872};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 128..146
FT /note="U2A'/phosphoprotein 32 family A C-terminal"
FT /evidence="ECO:0000259|SMART:SM00446"
FT REGION 147..281
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 161..178
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 179..193
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 194..262
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 281 AA; 32214 MW; 6948A526B1CB2B92 CRC64;
MDMKKRIHLE LRNRTPSDVK ELVLDNCRSY EGKIEGLTDE FEELEFLSTI NVGLTSVANL
PKLNKLKKLE LSDNRISGGL EVLAEKCPNL THLNLSGNKI KDLGTIEPLK KLENLKSLDL
FNCEVTNLND YRENVFKLLP QLTYLDGYDR DDKEAPDSDA EGYVEGLDDE EEDEDVLSLV
KDRDDKEAPD SDAEGYVEGL DDEEEDEDEE EYDDDAQVVE DEEDEEEEEE GEEEDVSGEE
EEDEEGYNDG EVDDDEDEDE PDEERGQKRK REPEDEGDED D
//
