ID A0A2I0ME64_COLLI Unreviewed; 844 AA.
AC A0A2I0ME64;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Transforming growth factor, beta receptor III, transcript variant X1 {ECO:0000313|EMBL:PKK27964.1};
GN Name=TGFBR3 {ECO:0000313|EMBL:PKK27964.1};
GN ORFNames=A306_00005800 {ECO:0000313|EMBL:PKK27964.1};
OS Columba livia (Rock dove).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Columbiformes; Columbidae; Columba.
OX NCBI_TaxID=8932 {ECO:0000313|EMBL:PKK27964.1, ECO:0000313|Proteomes:UP000053872};
RN [1] {ECO:0000313|EMBL:PKK27964.1, ECO:0000313|Proteomes:UP000053872}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC TISSUE=Blood {ECO:0000313|EMBL:PKK27964.1};
RX PubMed=23371554; DOI=10.1126/science.1230422;
RA Shapiro M.D., Kronenberg Z., Li C., Domyan E.T., Pan H., Campbell M.,
RA Tan H., Huff C.D., Hu H., Vickrey A.I., Nielsen S.C., Stringham S.A.,
RA Hu H., Willerslev E., Gilbert M.T., Yandell M., Zhang G., Wang J.;
RT "Genomic diversity and evolution of the head crest in the rock pigeon.";
RL Science 339:1063-1067(2013).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PKK27964.1}.
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DR EMBL; AKCR02000018; PKK27964.1; -; Genomic_DNA.
DR RefSeq; XP_005498782.1; XM_005498725.1.
DR AlphaFoldDB; A0A2I0ME64; -.
DR STRING; 8932.A0A2I0ME64; -.
DR GeneID; 102094284; -.
DR KEGG; clv:102094284; -.
DR CTD; 7049; -.
DR InParanoid; A0A2I0ME64; -.
DR OrthoDB; 2949260at2759; -.
DR Proteomes; UP000053872; Unassembled WGS sequence.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR Gene3D; 2.60.40.4100; Zona pellucida, ZP-C domain; 1.
DR Gene3D; 2.60.40.3210; Zona pellucida, ZP-N domain; 1.
DR InterPro; IPR042235; ZP-C.
DR InterPro; IPR048290; ZP_chr.
DR InterPro; IPR001507; ZP_dom.
DR InterPro; IPR017977; ZP_dom_CS.
DR PANTHER; PTHR14002; ENDOGLIN/TGF-BETA RECEPTOR TYPE III; 1.
DR PANTHER; PTHR14002:SF7; TRANSFORMING GROWTH FACTOR BETA RECEPTOR TYPE 3; 1.
DR Pfam; PF00100; Zona_pellucida; 1.
DR PRINTS; PR00023; ZPELLUCIDA.
DR SMART; SM00241; ZP; 1.
DR PROSITE; PS00682; ZP_1; 1.
DR PROSITE; PS51034; ZP_2; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000313|EMBL:PKK27964.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000053872};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..844
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5014190444"
FT TRANSMEM 778..802
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 451..725
FT /note="ZP"
FT /evidence="ECO:0000259|PROSITE:PS51034"
FT REGION 528..547
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 810..844
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 530..544
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 844 AA; 93251 MW; F0AE2E7F9528509B CRC64;
MSSSCVTSVF ALMILCFAAA GPVPRSECVL SPVNDSHPVH ALLESFTVLS GCASRGTTGL
PQEVHVLNLR NPEEGLGNHE REVTLHLNPI SSVHIHQKPL VFLLNSPLPL VWKLKTERLA
PGIRRVFFVS LGSVVQFEKG NFSLSAETEE KVFPEKNEHL LQWAQKEYGA VTSFTELKIS
RNIYIKVGED QVFPPSCNIE KNFLSLNYLA GYLQPKTAEG CLMSNLIQER EVHIIELITP
NSNPYSAFQV DIIVDIKPSQ PGAKLVRDVV LILKCKKSVN WVIKSHDVQG KLEVITSNSV
GFGKETERSM TMSKSVRPDI PSSYESLIKW AYEHNYRPVT SYTKAPVANR FHLQLEDTEE
MNDEEDHSLP PELTELLGVN PLPAPKNPAL SDGLAFPFHI NRGRHDTVGE GIFPSRDSVD
TLINHDFGHS LSKHKEPEEV QGSADVALSI KCDDKVMTVA VEKDSLQASG YTRTELSLLD
HSCKAKMNGT HFILESLLNK CGTRTAYVLN KIVYFNSIVI QLSSPAESSG FDDDDMESGD
NGFPGDADEG DVTFSSWPEI AFNCTLHQPE DDRGISWPPE PHITNVTFNM ELYKTDLFLA
PSQGLFSVAE NGPIYVEVSV TKADRSLGFA IQTCFVSPFS NPDRMSDYTI IENICPKDES
VKFYSIEKVN FPIPHAQKDK KRFSFVFKPM FNISLLFLHC ELTLCTNKDK DTQGLPKCIP
PDEACTSLNV DMILAMMHNK KTFTKPLVVI THEGKLEDSS LPKPNVRQPP VFYGLDTLTV
VGIAFAAFVI GALLTGALWF IYSHTGEAAG RQQVPTSPPA SENSSAAHSI GSTQSTPCSS
SSAT
//
